| 1. |
- Kanai, M, et al.
(författare)
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- 2023
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swepub:Mat__t
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| 2. |
- Niemi, MEK, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 3. |
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| 4. |
- Wroldsen, Kim Jarle, 1990-
(författare)
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Hand-in-Hand in the Peach Flower Land : Analysis of Huí Cadre Agency in the Literature Propaganda Magazine Kāidū River in the North-West Borderland of China
- 2023
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis studies how mínzú (ethnic) agency is effectuated through propaganda literature among Muslim minority cadres in the Yānqí Huí Autonomous County of the Xīnjiāng Uyghur Autonomous Region of North-West China in the 2010s. The aim is to understand to what extent and in what ways mínzú identification can have a socio-politically significant impact on the activities of mínzú cadres in a restrictive environment and in a medium where mínzú agency is controversial and difficult to implement. The thesis is motivated on the one hand by studies that presume the “monolithic” nature of cadres that speak the language of the Party-State, and on the other hand by studies that too readily presume that the invocation of Party-State orthodoxy is mere lip-service paid to authorities.The questions are approached by studying the implications that the cadre writers’ literary activities have on Huí mínzú identity in the context of the discourses that they invoke. In the process, national concerns are contrasted to mínzú concerns in order to evaluate and ascertain the intentional nature behind the invocation of mínzú concerns.The implications of the writers’ literary activities are identified by studying the role that they play in the discursive context of the literary Kāidū River magazine. The study finds that the discursive context can best be described as hybrid in nature, involving the three “sub” discourses of Neo-Confucian cosmology, Republican race theory, and Maoist thought transformation. The first revolves around a notion of cosmic truth, the second around the significance of mínzú or nations, and the third around the threats of and safeguards against ideological pollution. By employing this hybrid discourse of truth, the writers legitimized their texts as state orthodoxy.Having identified the implications relevant for the formulation of Huí identity, the thesis describes the ways in which the Muslim minority cadres attempted to address mínzú concerns. Although national concerns permeated the texts of the Kāidū River, the writers demonstrated awareness of and the ability to work around the restrictions of Party-State discourse during the early 2010s—at least to some extent. Through selective interpretation, they legitimized off-center views while remaining within the discourse of "truth.”The thesis demonstrates how the intention of mínzú authors can be identified by studying the implications of their texts in the discursive context within which they are embedded, even when these implications are multivalent. Significantly, the thesis is able to do so by studying how relevant implications consistently are invoked and examining the degree of tolerance for contradictory meaning.
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| 6. |
- Allwell-Brown, Gbemisola
(författare)
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Antibiotic use among children in low- and middle-income countries : Studies on global trends, and contextual determinants of antibiotic prescribing in Eastern Uganda
- 2022
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis aimed to systematically map trends in reported antibiotic use (RAU) among sick under-five children across low- and middle-income countries (LMICs) in 2005-2017, and, to understand the contextual determinants of antibiotic prescribing in Eastern Uganda. Based on 132 national surveys from 73 LMICs, and using Bayesian linear regression models, trends in RAU among sick under-five children (with symptoms of fever, diarrhoea or cough with fast/difficult breathing) across LMICs in 2005-2017 were mapped by WHO region, World Bank country income group, symptom complaint (Study-I), and by the following user characteristics: rural/urban residence, maternal education, household wealth and source of care (Study-II). To provide context, Study-III investigated patterns and contextual determinants of antibiotic prescribing for febrile under-five outpatients (FUO) attending 37 primary and secondary healthcare facilities across Bugisu, a sub-region in Eastern Uganda, based on a healthcare facility survey, and a two-year retrospective review of outpatient registers from January 2019-December 2020. To further strengthen the understanding of contextual determinants of antibiotic prescribing, in Study-IV, 10 focus group discussions and 10 in-depth interviews were conducted with 85 healthcare providers across primary and secondary healthcare facilities in Bugisu, and analysed using thematic analysis.A modest (17%) relative increase in RAU for sick under-five children across LMICs in 2005-2017 was found, with about 43% of the children reportedly receiving antibiotics for their illness in 2017. Low-income, African, and South-East Asian countries consistently recorded the lowest RAU for sick under-five children. Within LMICs, RAU for sick under-five children increased across all user groups in 2005-2017 but remained lowest among the poorest children, those living in rural areas, and having mothers with the lowest education levels. In Bugisu, 62.2% of FUO in surveyed healthcare facilities received antibiotic prescriptions. Amoxicillin and co-trimoxazole accounted for two-thirds of all antibiotic prescriptions. Cotrimoxazole and ampicillin/cloxacillin were prescribed, despite not being indicated in any of the reported conditions in Study-III. Among other interrelated factors across multiple levels of the health system, availability of antibiotics and diagnostics within healthcare facilities, caregiver demands, and governance at national and sub-national levels were important health worker considerations in antibiotic prescribing for febrile under-five patients.These studies suggest that inequitable access to antibiotics remains a challenge between and within LMICs. Yet, misuse and wastage of antibiotics persists in the same populations with the greatest lack of access to antibiotics and formal healthcare services. A health systems strengthening approach is required to improve antibiotic stewardship and overall quality of care in LMICs.
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| 7. |
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| 8. |
- Dareng, EO, et al.
(författare)
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Polygenic risk modeling for prediction of epithelial ovarian cancer risk
- 2022
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Ingår i: European journal of human genetics : EJHG. - : Springer Science and Business Media LLC. - 1476-5438 .- 1018-4813. ; 30:3, s. 349-362
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Tidskriftsartikel (refereegranskat)abstract
- Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects in models could improve predictive performance over standard approaches of PRS construction. Here, we implemented computationally efficient, penalized, logistic regression models (lasso, elastic net, stepwise) to individual level genotype data and a Bayesian framework with continuous shrinkage, “select and shrink for summary statistics” (S4), to summary level data for epithelial non-mucinous ovarian cancer risk prediction. We developed the models in a dataset consisting of 23,564 non-mucinous EOC cases and 40,138 controls participating in the Ovarian Cancer Association Consortium (OCAC) and validated the best models in three populations of different ancestries: prospective data from 198,101 women of European ancestries; 7,669 women of East Asian ancestries; 1,072 women of African ancestries, and in 18,915 BRCA1 and 12,337 BRCA2 pathogenic variant carriers of European ancestries. In the external validation data, the model with the strongest association for non-mucinous EOC risk derived from the OCAC model development data was the S4 model (27,240 SNPs) with odds ratios (OR) of 1.38 (95% CI: 1.28–1.48, AUC: 0.588) per unit standard deviation, in women of European ancestries; 1.14 (95% CI: 1.08–1.19, AUC: 0.538) in women of East Asian ancestries; 1.38 (95% CI: 1.21–1.58, AUC: 0.593) in women of African ancestries; hazard ratios of 1.36 (95% CI: 1.29–1.43, AUC: 0.592) in BRCA1 pathogenic variant carriers and 1.49 (95% CI: 1.35–1.64, AUC: 0.624) in BRCA2 pathogenic variant carriers. Incorporation of the S4 PRS in risk prediction models for ovarian cancer may have clinical utility in ovarian cancer prevention programs.
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| 9. |
- Garozzo, Lucia M.
(författare)
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Exploring effective descriptions of gauge fields and strings : A Lagrangian approach with insights from color-kinematics duality
- 2024
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The concept of a color-kinematics duality is an important driving force in advancing the modern understanding of scattering amplitudes, in both field theory and string theory. Yet, open questions remain that motivate the need for a deeper understanding of the duality. A central open question is: do the kinematic numerators admit a Lie-algebraic origin, just like the corresponding color factors? The answer may be intimately related to a detailed understanding of the duality at the level of the Lagrangian. For pure Yang-Mills theory, a cubic Lagrangian which directly computes color-dual numerators is not yet known. In this thesis, we make progress in this direction by constructing a cubic Lagrangian in terms of the ordinary gauge field and a set of auxiliary fields. The contributions to the numerators are split into independent sectors specified by the number of contractions between polarization vectors. We find a novel Lagrangian with a finite number of fields and interactions that computes color-dual Yang-Mills numerators to any multiplicity, valid for sectors with up to two polarization contractions. In the context of string theory, insights from the color-kinematics duality have revealed interesting relations between string and field theory amplitudes. The sector of open bosonic string amplitudes where transcendental numbers are absent is known to be described by a higher-derivative field theory. The spectrum of this theory includes a massless gauge field and extra massive modes: by integrating the latter out from the Lagrangian, we obtain an expansion in the inverse string tension, which is a low-energy effective description of the dynamics of the massless modes of the bosonic string. This thesis develops the general method and explicitly writes down the operators entering the effective Lagrangian through fourth order in the inverse string tension.
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| 12. |
- Holmefur, Marie, 1968-, et al.
(författare)
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Evaluation of the "Let's Get Organized" group intervention to improve time management : protocol for a multi-centre randomised controlled trial
- 2021
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Ingår i: Trials. - : BioMed Central. - 1745-6215. ; 22:1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Time management skills are essential for living in modern society. People with mental or neurodevelopmental disorders typically have cognitive limitations, including affected time management, which might lead to poor occupational balance, low self-efficacy, and poor parental sense of competence. "Let's Get Organized" (LGO) is a recently developed manual-based group intervention to train time management skills. The aim of this trial is to evaluate the efficiency of the Swedish version of LGO (LGO-S) compared to treatment as usual (individual occupational therapy) to improve time management for adults with impaired time management skills due to mental or neurodevelopmental disorders. Furthermore, to evaluate if the intervention is a cost-effective way to improve the quality of life and time management skills of these individuals, we will conduct a health economic evaluation.METHODS: The trial will have a multi-centre, open, parallel randomised controlled design. A total of 104 adults with cognitive limitations due to mental or neurodevelopmental disorders will be recruited from open psychiatric or habilitation care units. Outcomes will be measured before and after a 10-week intervention, with a follow-up 3 months after completing the intervention. The primary outcome will be self-assessed time management skills. Secondary outcomes will be e.g. self-assessed skills in organisation and planning, regulation of emotions, satisfaction with daily occupations, occupational balance, self-efficacy, and quality-adjusted life years.DISCUSSION: A recent feasibility study has shown promising results for LGO-S, and a randomised trial will provide robust evidence for the possible efficacy of LGO-S in comparison to treatment as usual.TRIAL REGISTRATION: ClinicalTrials.gov NCT03654248 . Registered on 20 August 2018.
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| 13. |
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| 14. |
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| 15. |
- Jandrić, Petar, et al.
(författare)
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Teaching in the Age of Covid-19
- 2020
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Ingår i: Postdigital Science and Education. - : Springer Science and Business Media LLC. - 2524-4868 .- 2524-485X. ; 2:3, s. 1069-1230
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- A collection of 84 author's testimonies and workspace photographs between 18 March and 5 May 2020.
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| 16. |
- Jandrić, Petar, et al.
(författare)
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Teaching in the Age of Covid-19—1 Year Later
- 2021
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Ingår i: Postdigital Science and Education. - : Springer. - 2524-485X .- 2524-4868. ; 3:3, s. 1073-1223
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Tidskriftsartikel (refereegranskat)
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| 17. |
- Khatri, C, et al.
(författare)
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Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
- 2021
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Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 11:11, s. e050830-
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Tidskriftsartikel (refereegranskat)abstract
- Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.ResultsThis study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p<0.001), age >80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).ConclusionsPatients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration numberNCT04323644
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| 18. |
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| 19. |
- Roshanai, Afsaneh, et al.
(författare)
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Psychometric Properties of the Original Version of the Assessment of Time Management Skills
- 2021
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Ingår i: American Journal of Occupational Therapy. - : American Occupational Therapy Association. - 0272-9490 .- 1943-7676. ; 75:Suppl. 2
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Time management is a key OT intervention component. Valid and reliable instruments are essential for evaluating rehabilitation and OT interventions. The results of this study show that the Assessment of Time Management Skills has good measurement properties and consistent and replicable items and is useful in English-speaking countries. It can provide valid measures of time management skills, organization and planning skills, and regulation of emotion in a general population and presumably also a population with cognitive impairment.
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| 20. |
- Roshanay, Afsaneh, et al.
(författare)
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The Psychometric Properties of the Original Version of Assessment of Time Management Skills (ATMS)
- 2022
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Ingår i: Occupational Therapy International. - : Wiley and Hindawi. - 0966-7903 .- 1557-0703. ; 2022
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Tidskriftsartikel (refereegranskat)abstract
- Background: To perform daily activities, time management and organizational skills are essential and therefore also important intervention focus in occupational therapy. To guide and evaluate intervention, valid and reliable instruments that measure time management and organization skills are necessary. The aim of this study was to evaluate the psychometric properties of the Assessment of Time Management Skills (ATMS).Methods: Eligible participants were volunteer adults from the general population who were aged between 18 and 65 years, had a good understanding of English, and were not currently involved in any training or education to improve time management. The ATMS was filled out as a computer-administered survey. Rasch measurement analysis was used to evaluate the validity and aspects of reliability of the ATMS.Results: In total, 241 adults (112 male and 129 female, mean age = 40) participated. The analysis of principal components of residuals (PCA) and the item goodness-of-fit indicated that the 30-item scale does not measure only one single trait. Three subscales, time management (11 items), organization and planning (11 items), and regulation of emotion (5 items), were detected. One item each on the 11-item subscale showed misfit, but they were kept due to high relevance. All three subscales showed excellent results on analyses of PCA, local independence, and reliability.Conclusions and Relevance: ATMS can provide valid measures of time management, organization and planning skills, and regulation of emotion in a general population and presumably also in a population with cognitive impairment. The measure is useful for occupational therapists in assessing patients' strengths and barriers in time management skills. It can also be useful in identifying the necessity of training time management skills, to guide OT intervention programs and to evaluate interventions.What This Article Adds: Knowledge about the psychometric properties and usefulness of the ATMS in English-speaking countries.
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| 21. |
- Straszer, Boglárka, fil.dr, professor, 1973-, et al.
(författare)
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Samhällsorientering med boken ”Om Sverige” : Rapport från ett samverkansprojekt om interaktion och interkulturella förhållningssätt i en digital lärmiljö
- 2023
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Föreliggande rapport är ett resultat av det samverkansprojekt som Interkulturellt Utvecklingscentrum Dalarna, IKUD, vid Högskolan Dalarna tillsammans med Ludvika Kommun, finansierat av Länsstyrelsen i Dalarnas län, startade under senhösten 2020 för att skapa kunskap om etableringsprogrammet Samhällsorientering för nyanlända med olika språkbakgrund under förändrade villkor som digitaliseringen medförde under pandemiåret 2021. Syftet med projektet har varit att bidra med en forskningsöversikt om digital lärmiljö utifrån best practice-erfarenheter från nationell och internationell forskning och att, utifrån en fallstudie om SO (situationen i Ludvika), resonera kring praktiker i digitala lärmiljöer. Fokus ligger på interaktion i en digital lärmiljö. Interkulturella förhållningssätt är också ett centralt tema. Ytterligare en viktig aspekt som undersöks är hur bilden av Sverige och den nyanlända skapas och uttrycks i klassrumsinteraktionen utifrån SO-läromedlet (boken Om Sverige). Utifrån syftet med projektet presenteras i rapporten (1) en kort forskningsöversikt om digital lärmiljö baserad på nationell och internationell forskning, (2) reflektioner utifrån observationer i en digital undervisningsmiljö i Ludvika kommun i samband med samhällsorienteringen, samt (3) en analys av undervisningsmaterialet som användes på de observerade lektionerna.
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| 22. |
- Thomas, M, et al.
(författare)
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Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity
- 2023
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Ingår i: medRxiv : the preprint server for health sciences. - : Cold Spring Harbor Laboratory.
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Polygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry data have sub-optimal performance in non-European ancestry populations, limiting their utility among these populations. Towards addressing this deficiency, we expanded PRS development for CRC by incorporating Asian ancestry data (21,731 cases; 47,444 controls) into European ancestry training datasets (78,473 cases; 107,143 controls). The AUC estimates (95% CI) of PRS were 0.63(0.62-0.64), 0.59(0.57-0.61), 0.62(0.60-0.63), and 0.65(0.63-0.66) in independent datasets including 1,681-3,651 cases and 8,696-115,105 controls of Asian, Black/African American, Latinx/Hispanic, and non-Hispanic White, respectively. They were significantly better than the European-centric PRS in all four major US racial and ethnic groups (p-values<0.05). Further inclusion of non-European ancestry populations, especially Black/African American and Latinx/Hispanic, is needed to improve the risk prediction and enhance equity in applying PRS in clinical practice.
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| 23. |
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| 25. |
- Wingren, Maria, 1976-, et al.
(författare)
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One-year follow-up after the time management group intervention Let's Get Organized
- 2022
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Ingår i: Scandinavian Journal of Occupational Therapy. - : Informa Healthcare. - 1103-8128 .- 1651-2014. ; 29:4, s. 305-314
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Time management skills are essential to maintain occupations in everyday life. People with neurodevelopmental or mental disorders often experience persistent difficulties with managing time and organizing daily life, consequently, there is a need to establish interventions with sustainable results.AIM: The aim was to perform a one-year post-intervention follow-up after the intervention Let's Get Organized (LGO-S) for people with neurodevelopmental or mental disorders.METHODS: The study is a one-year follow-up of a single group pre-test-post-test design. Thirty-eight persons with difficulties in time management due to neurodevelopmental or mental disorders participated. Instruments to collect data were Assessment of Time Management Skills; Weekly Calendar Planning Activity and the Satisfaction with Daily Occupations instrument. Wilcoxons's signed-rank test was used to compare data over time.RESULTS: There were no significant differences in the participants' outcomes between post-intervention and one-year follow-up in time management skills and regulation of emotions, satisfaction with daily occupations, and global satisfaction. A significant improvement could be seen in the subscale organization and planning at the one-year follow-up compared to post-intervention.CONCLUSIONS: Improvements in time management skills, organization, and planning, regulation of emotions, and satisfaction with daily occupations after the LGO-S can be maintained in the long term.
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| 26. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 27. |
- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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