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| 2. |
- Guo, Xiao-Hua, et al.
(författare)
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Advanced glycation end products induce actin rearrangement and subsequent hyperpermeability of endothelial cells
- 2006
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Ingår i: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. - : Wiley. - 1600-0463 .- 0903-4641. ; 114:12, s. 874-883
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Tidskriftsartikel (refereegranskat)abstract
- This study aimed to determine the effects of advanced glycation end products (AGEs) on endothelial cytoskeleton morphology and permeability, and to detect the underlying signaling mechanisms involved in these responses. Cultured endothelial cells (ECs) were exposed to AGE-modified human serum albumin (AGE-HSA), and EC cytoskeletal changes were evaluated by observing fluorescence of F-actin following ligation with labeled antibodies. Endothelial permeability was detected by measuring the flux of TRITC-albumin across the EC monolayers. To explore the signaling pathways behind AGE-induced EC alteration, ECs were treated with either soluble anti-AGE receptor (RAGE) IgG, or the MAPK inhibitors PD98059 and SB203580 before AGE-HSA administration. To further elucidate possible involvement of the ERK and p38 pathways in AGE-induced EC changes, adenovirus-carried recombinant constitutive dominant-negative forms of upstream ERK and p38 kinases, namely MEK1(A) and MKK6b(A), were pre-infected into ECs 24 h prior to AGE-HSA exposure. AGE-HSA induced actin cytoskeleton rearrangement, as well as EC hyperpermeability, in a dose and time-dependent manner. The effects were attenuated in cells pretreated with anti-RAGE IgG, PD98059 or SB203580, respectively. EC pre-infection with MEK1(A) and MKK6b(A) also alleviated the effect of AGEs. Furthermore, adenovirus-mediated administration of activated forms of either MEK1 or MKK6b alone induced rearrangement of F-actin and hyperpermeability. The results indicate that ERK and p38 MAPK play important roles in the mediation of AGE-induced EC barrier dysfunction associated with morphological changes of the F-actin.
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| 3. |
- Liu, Hui, et al.
(författare)
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Confinement effect on scattering states in a thin lead film: Field-induced resonance states in the high-bias regime of scanning tunneling microscopy
- 2007
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Ingår i: Physical Review B. ; 76:11
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Tidskriftsartikel (refereegranskat)abstract
- Field-induced resonance states in the high-bias regime of scanning tunneling microscopy are used to couple and probe the scattering states above the vacuum level in a thin lead film. The resonance energies show a bilayer oscillation as a function of film thickness. Theoretical modeling unveils that the oscillation results from the confinement of the highly excited scattering states by the quantum well, yielding a bilayer phase modulation at the boundaries where they are coherently coupled to the external states.
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| 4. |
- Tian, Jie, et al.
(författare)
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Optical Quality Improvement of Si Photonic Devices Fabricated by Focused-Ion-Beam Milling
- 2009
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Ingår i: Journal of Lightwave Technology. - 0733-8724 .- 1558-2213. ; 27:19, s. 4306-4310
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Tidskriftsartikel (refereegranskat)abstract
- Focused-ion-beam directly milling strategy was used to fabricate photonic resonators on crystalline silicon-on-insulator substrate. In order to reduce damages such as implanting ions, amorphous layers and re-deposition process which are induced by the ions, a sacrificed silica layer was used as an etching mask and a silicon thermal oxidation process was performed. The transmission spectra of both photonic crystal cavities and micro-ring resonators were measured. The resulting data demonstrate that the Q factors are significantly improved after the oxidation treatment.
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| 5. |
- Yan, Jun, et al.
(författare)
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End and Central Plasmon Resonances in Linear Atomic Chains
- 2007
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Ingår i: Phys. Rev. Lett.. ; 98, s. 216602-
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Tidskriftsartikel (refereegranskat)abstract
- The existence and nature of end and central plasmon resonances in a linear atomic chain, the 1D analog to surface and bulk plasmons in 2D metals, has been predicted by ab initio time-dependent density functional theory. Length dependence of the absorption spectra shows the emergence and development of collectivity of these resonances. It converges to a single resonance in the longitudinal mode, and two transverse resonances, which are localized at the ends and center of the atom chains. These collective modes bridge the gaps, in concept and scale, between the collective excitation of atomic physics and nanoplasmonics. It also outlines a route to atomic-scale engineering of collective excitations.
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| 6. |
- Yan, Jun, et al.
(författare)
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Plasmon resonances in linear atomic chains: Free-electron behavior and anisotropic screening of d electrons
- 2008
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Ingår i: Physical Review B. - 1098-0121. ; 78:23, s. 235413-
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Tidskriftsartikel (refereegranskat)abstract
- Electronic excitations in linear atomic chains of simple and noble metals (silver) have been studied using time-dependent density-functional theory. The formation and development of collective resonances in the absorption spectra were obtained as functions of the chain length. A longitudinal collective resonance appears in both simple- and noble-metal chains. Its dispersion has been deduced and is compared with that of a one-dimensional electron gas. The transverse excitation generally shows a bimodal structure, which can be assigned as the “end and central resonances.” The d electrons of silver atoms reduce both the energies and intensities of the transverse modes but have little effect on its longitudinal resonance. This anisotropic screening is determined by the interband (d→p) transition, which is involved only in transverse oscillations. Analysis of these results yields a general picture of plasmon resonances in one-dimensional atomic structures. Implications of such atomic-scale plasmons to surface plasmons in larger dimensions are also discussed.
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| 8. |
- Zhang, Zhi, et al.
(författare)
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Two-layered wireless sensor networks for warehouses and supermarkets
- 2009
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The rapid development of wireless sensor network and RFID technologies offers a wide range of novel applications and services. In this paper, we present a two-layered wireless network for warehouses and supermarkets to monitor goods storage and sale, and assist for quality management and market analysis. The hierarchical architecture uses IEEE 802.15.4a impulse ultra-wideband radio (IR-UWB) communication protocol between slave sensor nodes and master sensor nodes, and IEEE 802.11b/g between master sensor nodes and server. The performance of our proposal is evaluated based on the widely used OMNeT++ simulation environment. Simulation results are presented and discussed according to different sampling rates and traffic loads for specific scenarios requirements. © 2009 IEEE.
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