| 1. |
- Lane, J. C. E., et al.
(författare)
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Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study
- 2020
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Ingår i: Lancet Rheumatology. - : Elsevier BV. - 2665-9913. ; 2:11
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Tidskriftsartikel (refereegranskat)abstract
- Background Hydroxychloroquine, a drug commonly used in the treatment of rheumatoid arthritis, has received much negative publicity for adverse events associated with its authorisation for emergency use to treat patients with COVID-19 pneumonia. We studied the safety of hydroxychloroquine, alone and in combination with azithromycin, to determine the risk associated with its use in routine care in patients with rheumatoid arthritis. Methods In this multinational, retrospective study, new user cohort studies in patients with rheumatoid arthritis aged 18 years or older and initiating hydroxychloroquine were compared with those initiating sulfasalazine and followed up over 30 days, with 16 severe adverse events studied. Self-controlled case series were done to further establish safety in wider populations, and included all users of hydroxychloroquine regardless of rheumatoid arthritis status or indication. Separately, severe adverse events associated with hydroxychloroquine plus azithromycin (compared with hydroxychloroquine plus amoxicillin) were studied. Data comprised 14 sources of claims data or electronic medical records from Germany, Japan, the Netherlands, Spain, the UK, and the USA. Propensity score stratification and calibration using negative control outcomes were used to address confounding. Cox models were fitted to estimate calibrated hazard ratios (HRs) according to drug use. Estimates were pooled where the I-2 value was less than 0.4. Findings The study included 956 374 users of hydroxychloroquine, 310 350 users of sulfasalazine, 323 122 users of hydroxychloroquine plus azithromycin, and 351 956 users of hydroxychloroquine plus amoxicillin. No excess risk of severe adverse events was identified when 30-day hydroxychloroquine and sulfasalazine use were compared. Selfcontrolled case series confirmed these findings. However, long-term use of hydroxychloroquine appeared to be associated with increased cardiovascular mortality (calibrated HR 1.65 [95% CI 1.12-2.44]). Addition of azithromycin appeared to be associated with an increased risk of 30-day cardiovascular mortality (calibrated HR 2.19 [95% CI 1.22-3.95]), chest pain or angina (1.15 [1.05-1.26]), and heart failure (1.22 [1.02-1.45]). Interpretation Hydroxychloroquine treatment appears to have no increased risk in the short term among patients with rheumatoid arthritis, but in the long term it appears to be associated with excess cardiovascular mortality. The addition of azithromycin increases the risk of heart failure and cardiovascular mortality even in the short term. We call for careful consideration of the benefit-risk trade-off when counselling those on hydroxychloroquine treatment. Copyright (c) 2020 The Author(s). Published by Elsevier Ltd.
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| 2. |
- Li, Han, et al.
(författare)
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A co-doped oxygen reduction catalyst with FeCu promotes the stability of microbial fuel cells
- 2022
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Ingår i: Journal of Colloid and Interface Science. - : ACADEMIC PRESS INC ELSEVIER SCIENCE. - 0021-9797 .- 1095-7103. ; 628, s. 652-662
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Tidskriftsartikel (refereegranskat)abstract
- Air cathode microbial fuel cell (AC-MFC) cannot be used on a large scale because of its low oxygen reduction reaction (ORR) efficiency. Despite the fact that bimetallic catalysts can greatly enhance the oxygen reduction rate by regulating the electronic structure of the active site, the flaws of insufficient exposure of the active site and easy metal agglomeration limit its catalytic activity. Herein, we report on the preparation of a stable heteroatomic substrate using a copper material organic framework as a precursor, covered by Fe-based active sites. As a result of dipole-dipole interactions, the reduced product Fe2+ forms a weak Fe-O surface that is conducive to the adsorption of active substances. The presence of Fe-0 enhances the electrical conductivity of the catalytic, thus promoting ORR efficiency. Through redox coupling, the D -band center of Fe at FeCu@CN is optimized and brought close to the Fermi level to facilitate electron transfer. Notably, FeCu@CN demonstrates a superior power density of 2796.23 +/- 278.58 mW m(-3), far exceeding that of Pt/C (1363.93 +/- 102.56 mW m(-3)), in the application of microbial fuel cells (MFCs). Meanwhile, the MFC-loaded FeCu@CN maintains excellent stability and outstanding output voltage after 1000 h, which provides feasibility for large-scale application. (C) 2022 Elsevier Inc. All rights reserved.
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| 3. |
- Li, You, et al.
(författare)
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Cross-Media Communications With Decode-and-Forward Relay and Optimal Power Allocation
- 2020
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Ingår i: IEEE Transactions on Vehicular Technology. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 0018-9545 .- 1939-9359. ; 69:8, s. 9201-9205
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Tidskriftsartikel (refereegranskat)abstract
- With the rapid development of wireless communications, the signals may be transmitted in different media, such as visible light and millimeter-wave along the communication path. In this case, there will be different devices working in different media, which cannot directly communicate to each other. For alleviating this problem, we first conceive a cross-media communication scenario where two devices for different media could communicate with the aid of a relay working in both media. Furthermore, we derive the average outage probability of the uplink and downlink communications. Finally, aiming at minimizing the derived average outage probability, the optimal power allocation (PA) scheme at the relay side is also derived and verified by simulation results.
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| 4. |
- Li, You, et al.
(författare)
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Preinvasion Assessment of Exotic Bark Beetle-Vectored Fungi to Detect Tree-Killing Pathogens
- 2022
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Ingår i: Phytopathology. - 0031-949X. ; 112:2, s. 261-270
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Tidskriftsartikel (refereegranskat)abstract
- Exotic diseases and pests of trees have caused continental-scale disturbances in forest ecosystems and industries, and their invasions are considered largely unpredictable. We tested the concept of preinvasion assessment of not yet invasive organisms, which enables empirical risk assessment of potential invasion and impact. Our example assesses fungi associated with Old World bark and ambrosia beetles and their potential to impact North American trees. We selected 55 Asian and European scolytine beetle species using host use, economic, and regulatory criteria. We isolated 111 of their most consistent fungal associates and tested their effect on four important southeastern American pine and oak species. Our test dataset found no highly virulent pathogens that should be classified as an imminent threat. Twenty-two fungal species were minor pathogens, which may require context-dependent response for their vectors at North American borders, while most of the tested fungi displayed no significant impact. Our results are significant in three ways; they ease the concerns over multiple overseas fungus vectors suspected of heightened potential risk, they provide a basis for the focus on the prevention of introduction and establishment of species that may be of consequence, and they demonstrate that preinvasion assessment, if scaled up, can support practical risk assessment of exotic pathogens.
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| 5. |
- Ma, Su-Min, et al.
(författare)
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The coarse-grained models of poly(ethylene oxide) and poly(propylene oxide) homopolymers and poloxamers in big multipole water (BMW) and MARTINI frameworks
- 2020
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Ingår i: Physical Chemistry, Chemical Physics - PCCP. - : Royal Society of Chemistry (RSC). - 1463-9076 .- 1463-9084. ; 22:28, s. 15976-15985
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Tidskriftsartikel (refereegranskat)abstract
- Polyethylene oxide (PEO) and poly(propylene oxide) (PPO), especially their tri-block copolymers PEO-PPO-PEO (poloxamers), have a broad range of applications in biotechnology and medical science. Understanding their specific interactions with biomembranes is the key to unveil the unique features of poloxamers either as membrane-healing or membrane pore-forming agents. Based on the coarse-graining convention of the MARTINI force field and the big multipole water (BMW) model, which has a three charged site topology and can reproduce the correct dipole moment of four-water clusters, we generated coarse-grained (CG) models with analytical and numerical potentials for PEO and PPO homopolymers and poloxamers in dilute solution. The effective bonded interaction potentials between CG beads were determined from the probability distributions of bond lengths, angles and dihedrals that are determined from atomistic simulations. The nonbonded interaction parameters were fine-tuned to reproduce the conformational properties of atomistic PEO and PPO homopolymers and poloxamersviaextensive CG simulations of PEO and PPO homopolymers and poloxamers in a BMW water environment. The reported CG models provide a promising framework for a comprehensive understanding of the microstructural, conformational, and dynamic properties of poloxamers and their delicate interactions with other species in an explicit water environment.
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| 6. |
- Wang, Hongyu, et al.
(författare)
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Co/Fe co-doped ZIF-8 derived hierarchically porous composites as high-performance electrode materials for Cu2+ions capacitive deionization
- 2023
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Ingår i: Chemical Engineering Journal. - : ELSEVIER SCIENCE SA. - 1385-8947 .- 1873-3212. ; 460
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Tidskriftsartikel (refereegranskat)abstract
- Due to a threat to human life from heavy metal ions pollution, unprecedented interest has been gained in the development of water purification technologies. Here, we explore another new approach to exploit a prospective carbon material for removing copper ions from aqueous solution based on rapid and easy capacitive deionization (CDI). Reasonable carbon materials modification with ideal composition and improved morphological structure is essential to additionally optimize the capabilities of CDI. We prepared a nitrogen-rich hierarchically porous carbon composites (CoFe-NC) with uniform cobalt (Co) and iron (Fe) doped metal in carbon skeleton by a simple impregnation and pyrolysis method, derived from zeolitic imidazolate framework-8, to use as highly effective CDI electrode for copper ions removal. The addition of Fe can facilitate the uniform dispersion of metals, and enable the formation of a stable carbon cage after pyrolysis. It can sufficiently expose active sites of the electrode materials and promote interfacial charge transfer, thus improving CDI electrosorption efficiency. CoFe-NC composites electrode can achieve outstanding deionization capacity (91.31 mg g-1) in 25 mg L-1 CuSO4 solu-tion. The carbon cage structure of CoFe-NC not only prevents aggregation of metals and avoids destruction of rich multistage pore system by pyrolysis, but also induces a faster ions transport rate. In addition, density functional theory calculations demonstrated that the co-doping of Co and Fe can remarkably increase the adsorption en-ergies of Cu2+ ions, leading to excellent selectivity, which indicates that CoFe-NC composites can be a desired CDI electrode material.
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| 7. |
- Wang, Hongyu, et al.
(författare)
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Exploration of selective copper ion separation from wastewater via capacitive deionization with highly effective 3D carbon framework-anchored Co(PO3)2 electrode
- 2024
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Ingår i: Separation and Purification Technology. - : ELSEVIER. - 1383-5866 .- 1873-3794. ; 336
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Tidskriftsartikel (refereegranskat)abstract
- The increasing amount of heavy metal copper ions (Cu2+) in industrial emissions, poses a serious threat to human health, biological environment, and resource scarcity. Capacitive deionization (CDI) is considered as a green and efficient method for desalination. It is crucial to develop high-performance electrodes for efficient operation of CDI that go beyond conventional carbon and yield considerable environmental benefits. Here, metal organic frameworks (MOFs) derived carbon-loaded cobalt metaphosphate (NC-Co(PO3)2) was prepared by lowtemperature gas-solid phosphating for Cu2+ removal as CDI electrode for the first time. NC-Co(PO3)2 demonstrated superior electrode structure and function due to the synergistic effects of electric double layer coupling PO bonds, the binding tendency of metaphosphate groups with Cu2+, and interfacial redox reactions induced by the labile valence state of cobalt. The optimal electrosorption capacity of NC-Co(PO3)2 was 95.41 mg g-1 at 1 V in 50 mL Cu2+ solution with splendid cyclic regeneration capability. Moreover, NC-Co(PO3)2 exhibited excellent selectivity and outstanding electrosorption performance in the presence of multiple coexisting ions and this CDI system realized the purification of actual copper-containing wastewater. A series of characterizations further revealed the specific mechanism of Cu2+ in adsorption-desorption process. Our finding strongly supported NCCo(PO3)2 electrode can extend the CDI platform's capability for effectively removing and retrieving Cu2+ from wastewater.
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| 8. |
- Wang, Yu-Cheng, et al.
(författare)
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Porous Carbon Membrane-Supported Atomically Dispersed Pyrrole-Type Fe-N-4 as Active Sites for Electrochemical Hydrazine Oxidation Reaction
- 2020
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Ingår i: Small. - : Wiley. - 1613-6810 .- 1613-6829. ; 16:31
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Tidskriftsartikel (refereegranskat)abstract
- The rational design of catalytically active sites in porous materials is essential in electrocatalysis. Herein, atomically dispersed Fe-N-x sites supported by hierarchically porous carbon membranes are designed to electrocatalyze the hydrazine oxidation reaction (HzOR), one of the key techniques in electrochemical nitrogen transformation. The high intrinsic catalytic activity of the Fe-N-x single-atom catalyst together with the uniquely mixed micro-/macroporous membrane support positions such an electrode among the best-known heteroatom-based carbon anodes for hydrazine fuel cells. Combined with advanced characterization techniques, electrochemical probe experiments, and density functional theory calculation, the pyrrole-type Fe-N-4 structure is identified as the real catalytic site in HzOR.
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| 9. |
- Xu, Weicheng, et al.
(författare)
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Nitrogen doping to accelerate the phase transition to ordered intermetallic Pt3Co catalyst for the oxygen reduction reaction in fuel cells
- 2023
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Ingår i: Journal of Materials Chemistry A. - : Royal Society of Chemistry (RSC). - 2050-7488 .- 2050-7496. ; 11:8, s. 4078-4087
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Tidskriftsartikel (refereegranskat)abstract
- Ordered intermetallic Pt–M alloys are foreseen to be promising as next-generation low-Pt catalysts for the oxygen reduction reaction (ORR) in proton exchange membrane fuel cells (PEMFCs) due to their high catalytic activity and stability. Nevertheless, the disorder-to-order intermetallic phase transition often needs to proceed at elevated annealing temperature for a long time, which leads to severe particle agglomeration. Herein, an efficient nitrogen (N)-doping strategy is developed to speed up such phase transition in an intermetallic Pt3Co alloy catalyst, which shortens the annealing duration by 3–5 fold at a temperature of 600–800 °C. Such a strategy can not only minimize the particle agglomeration but also effectively optimize the electronic structure of surface Pt atoms with the incorporated N. The prepared N-doped ordered intermetallic Pt3Co catalyst exhibits high ORR activity among the best of the state-of-the-art, with mass activities of 1.21 and 1.20 A mgPt−1 at 0.90 V in rotating disk electrode (RDE) and proton exchange membrane fuel cell (PEMFC) tests, respectively. Moreover, with the total Pt loading of 0.15 mgPt cm−2, the H2–air PEMFC delivers a power density of 1.27 W cm−2 at 150 kPaabs and 0.6 V, corresponding to a high Pt utilization of 0.118 gPt kW−1 that has surpassed the DOE 2025 target (0.125 gPt kW−1). This study paves a new way to develop high-performance low-Pt ORR catalysts for PEMFCs.
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| 10. |
- Yao, Zehan, et al.
(författare)
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Magnetization-induced optical rectification and inverse spin Hall effect for interfacial terahertz generation in metallic heterostructures
- 2021
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Ingår i: Physical Review B. - 2469-9950. ; 103:20
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Tidskriftsartikel (refereegranskat)abstract
- Metallic heterostructure as promising terahertz (THz) spintronic emitters has promoted the development of both spintronics and THz science. However, the underlying physics at the metallic interface, such as the nonlinear optical effect, remains unclear. Herein, we present interface magnetization induced THz generation from metallic heterostructure consisting of Heusler alloy CoFeMnSi (CFMS) and Pd thin films. THz generation is ascribed to 35% contribution from the magnetization-induced optical rectification (MOR) and 65% contribution from inverse spin Hall effect (ISHE) based on the pump polarization and sample azimuthal angle dependent measurement. Furthermore, the contribution ratio of the MOR decreases to 12% via lowering the CFMS grown temperature, which is due to the reduced crystalline quality and possible metal to semiconductor transformation in CFMS. Our results not only clarify MOR and ISHE in metallic heterostructure for the scientific field, but they also benefit THz source optimization for the technology field.
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| 11. |
- You, Henghui, et al.
(författare)
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Novel Strontium/Iron Bimetallic Carbon Composites as Synergistic Catalyst for Oxygen Reduction Reaction in Microbial Fuel Cells
- 2021
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Ingår i: Electrocatalysis. - : SPRINGER. - 1868-2529 .- 1868-5994. ; 12:6, s. 759-770
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Tidskriftsartikel (refereegranskat)abstract
- It is critical to develop non-noble metal (NNM) electrocatalysts with excellent stability and innovative activity for oxygen reduction reaction (ORR) in the microbial fuel cells (MFCs), which is a promising energy conversion technology. Herein, the preparation of iron carbide electrocatalysts (SrCO3/Fe3C) by the pyrolysis of a bimetal precursor (Sr and Fe) is proposed as a feasible strategy to realize a highly active electrocatalyst for ORR. Based on the catalytic potential of Sr-based materials, Fe species doping can provide more beneficial active sites for ORR. Concisely, the SrCO3/Fe3C(1:12) catalyst achieves the onset potential of 0.197 V (vs. Ag/AgCl) superior than Pt/C catalyst (0.193 V vs. Ag/AgCl) and the half-wave potential of -0.157 V (vs. Ag/AgCl) in 0.1-M KOH solution. Furthermore, the electrocatalyst exhibits nearly four-electron pathway, and generates less than 3% H2O2. Compared with Pt/C catalyst, it possesses preferable stability and superior methanol tolerance. Moreover, a composite electrode with SrCO3/Fe3C(1:12) as a catalyst on the carbon cloth demonstrated a superb air cathode in MFCs with a power density of 398.98 mW m(-2), which can outperform than 10 wt% Pt/C catalysts (342.13 mW m(-2)) on MFCs.
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| 12. |
- You, Lei, et al.
(författare)
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A Note on Decoding Order in User Grouping and Power Optimization for Multi-Cell NOMA With Load Coupling
- 2021
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Ingår i: IEEE Transactions on Wireless Communications. - : Institute of Electrical and Electronics Engineers (IEEE). - 1536-1276 .- 1558-2248. ; 20:1, s. 495-505
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Tidskriftsartikel (refereegranskat)abstract
- In this technical note, we present a new theoretical result for multi-cell non-orthogonal multiple access (NOMA). For multi-cell scenarios, a so-called load-coupling model has been proposed earlier to characterize the presence of mutual interference for NOMA, and the optimization process relies on the use of fixed-point iterations across cells. One difficulty here is that the order of decoding for successive interference cancellation (SIC) in NOMA is generally not known a priori. This is because the decoding order in one cell depends on interference, which, in turn, is governed by resource usage in other cells, and vice versa. To achieve convergence, previous works have used workarounds that pose restrictions to NOMA, such that the SIC decoding order remains throughout the fixed-point iterations. As a comment to the previous works, we derive and prove the following result: The convergence is guaranteed, even if the order changes over the iterations. The result not only waives the need of previous workarounds, but also implies that a wide class of optimization problems for multi-cell NOMA is tractable, as long as that for single cell is.
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| 13. |
- You, Lei, et al.
(författare)
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User-centric Performance Optimization with Remote Radio Head Cooperation in C-RAN
- 2020
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Ingår i: IEEE Transactions on Wireless Communications. - 1536-1276 .- 1558-2248. ; 19:1, s. 340-353
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Tidskriftsartikel (refereegranskat)abstract
- In a cloud radio access network (C-RAN), distributed remote radio heads (RRHs) are coordinated by baseband units (BBUs) in the cloud. The centralization of signal processing provides flexibility for coordinated multipoint transmission (CoMP) of RRHs to cooperatively serve user equipments (UEs). We target enhancing UEs' capacity performance, by jointly optimizing the selection of RRHs for serving UEs, i.e., CoMP selection, and resource allocation. We analyze the computational complexity of the problem. Next, we prove that under fixed CoMP selection, the optimal resource allocation amounts to solving a so-called iterated function. Towards user-centric network optimization, we propose an algorithm for the joint optimization problem, aiming at scaling up the capacity maximally for any target UE group of interest. The proposed algorithm enables network-level performance evaluation for quality of experience.
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| 14. |
- Yu, Zhanwei, et al.
(författare)
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Leveraging Muiti-cell NOMA for Cell Edge
- 2020
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Ingår i: 2020 IEEE International Conference on Advanced Networks and Telecommunications Systems (IEEE ANTS). - : Institute of Electrical and Electronics Engineers (IEEE). - 9781728192901
-
Konferensbidrag (refereegranskat)abstract
- Non-orthogonal multiple access (NOMA) is a promising technique for performance enhancement in cellular networks. This paper investigates how much NOMA can offer for cell edge in multi-cell scenarios. We consider the joint optimization problem of time-frequency resource allocation, user pairing, and power split, for scaling up the demand delivered for edge users. Our approach for problem solving consists in iteratively applying a fixed-point method to the cells, and, for each cell, deriving an algorithm guaranteeing optimum for single-cell optimization. By embedding the fixed-point method into bi-section search, we are able to show the overall approach guarantees global optimality. Numerical results demonstrate that multi-cell NOMA optimization has much more to offer over orthogonal multiple access for the experience of edge users, in particular for high-demand and resource-limited scenarios.
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| 15. |
- Zhang, Hongguo, et al.
(författare)
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Cu-doped CaFeO3 perovskite oxide as oxygen reduction catalyst in air cathode microbial fuel cells
- 2022
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Ingår i: Environmental Research. - : ACADEMIC PRESS INC ELSEVIER SCIENCE. - 0013-9351 .- 1096-0953. ; 214
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Tidskriftsartikel (refereegranskat)abstract
- Cathode electrocatalyst is quite critical to realize the application of microbial fuel cells (MFCs). Perovskite oxides have been considered as potential MFCs cathode catalysts to replace Pt/C. Herein, Cu-doped perovskite oxide with a stable porous structure and excellent conductivity was successfully prepared through a sol-gel method. Due to the incorporation of Cu, CaFe0.9Cu0.1O3 has more micropores and a larger surface area, which are more conducive to contact with oxygen. Doping Cu resulted in more Fe3+ in B-site and thus enhanced its binding capability to oxygen molecules. The data from electrochemical test demonstrated that the as-prepared catalyst has good conductivity, high stability, and excellent ORR properties. Compared with Pt/C catalyst, CaFe0.9Cu0.1O3 exhibits a lower overpotential, which had an onset potential of 0.195 V and a half-wave potential of 0.224 V, respectively. CaFe0.9Cu0.1O3 displays an outstanding four-electron pathway for ORR mechanism and demonstrates superiors corrosion resistance and stability. The MFC with CaFe0.9Cu0.1O3 has a greater maximum power density (1090 mW m(-3)) rather than that of Pt/C cathode (970 mW m(-3)). This work demonstrated CaFe0.9Cu0.1O3 is an economic and efficient cathodic catalyst for MFCs.
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| 16. |
- Zhang, Lei, et al.
(författare)
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A window–space-directed assembly strategy for the construction of supertetrahedron-based zeolitic mesoporous metal–organic frameworks with ultramicroporous apertures for selective gas adsorption
- 2021
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Ingår i: Chemical Science. - : Royal Society of Chemistry. - 2041-6520 .- 2041-6539. ; 12:16, s. 5767-5773
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Tidskriftsartikel (refereegranskat)abstract
- Despite their scarcity due to synthetic challenges, supertetrahedron-based metal–organic frameworks (MOFs) possess intriguing architectures, diverse functionalities, and superb properties that make them in‑demand materials. Employing a new window–space-directed assembly strategy, a family of mesoporous zeolitic MOFs have been constructed herein from corner-shared supertetrahedra based on homometallic or heterometallic trimers [M3(OH/O)(COO)6] (M3 = Co3, Ni3 or Co2Ti). These MOFs consisted of close-packed truncated octahedral cages possessing a sodalite topology and large β-cavity mesoporous cages (~22 Å diameter) connected by ultramicroporous apertures (~5.6 Å diameter). Notably, the supertetrahedron-based sodalite topology MOF composed with the Co2Ti trimer exhibited high thermal and chemical stability as well as the ability to efficiently separate acetylene (C2H2) from carbon dioxide (CO2).
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| 17. |
- Zhao, Xue-Ke, et al.
(författare)
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Focal amplifications are associated with chromothripsis events and diverse prognoses in gastric cardia adenocarcinoma
- 2021
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Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 12
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Tidskriftsartikel (refereegranskat)abstract
- The role of focal amplifications and extrachromosomal DNA (ecDNA) is unknown in gastric cardia adenocarcinoma (GCA). Here, we identify frequent focal amplifications and ecDNAs in Chinese GCA patient samples, and find focal amplifications in the GCA cohort are associated with the chromothripsis process and may be induced by accumulated DNA damage due to local dietary habits. We observe diverse correlations between the presence of oncogene focal amplifications and prognosis, where ERBB2 focal amplifications positively correlate with prognosis and EGFR focal amplifications negatively correlate with prognosis. Large-scale ERBB2 immunohistochemistry results from 1668 GCA patients show survival probability of ERBB2 positive patients is lower than that of ERBB2 negative patients when their surviving time is under 2 years, however, the tendency is opposite when their surviving time is longer than 2 years. Our observations indicate that the ERBB2 focal amplifications may represent a good prognostic marker in GCA patients.
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| 18. |
- Zhao, Yi, et al.
(författare)
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Delivering more to cell edge via joint multi-cell non-orthogonal multiple access and traffic offloading
- 2021
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Ingår i: IET Networks. - : Institution of Engineering and Technology. - 2047-4954 .- 2047-4962. ; 10:6, s. 265-277
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Tidskriftsartikel (refereegranskat)abstract
- We consider leveraging the joint potential of non-orthogonal multiple access (NOMA) and traffic offloading to benefit cell-edge users in multi-cell scenarios. We formulate the edge-driven throughput maximisation problem where both the offloading decision and resource allocation are to be optimised, accounting for the impact of the inter-cell interference on the decoding order in NOMA. The inter-cell interference is not given constants as it is influenced by resource allocation. Therefore the non-orthogonal multiple access (NOMA) decoding order is not known a priori. We explore the problem by decomposing it into two subproblems. By analysis of structural properties, we derive algorithm modules which interact iteratively for reciprocity, forming the overall algorithm. Numerical results show that the proposed scheme considerably improves the cell-edge throughput, compared with the conventional scheme of orthogonal multiple access without traffic offloading.
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| 19. |
- Zhong, Kengqiang, et al.
(författare)
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Facile gas-steamed synthesis strategy of N, F co-doped defective porous carbon for enhanced oxygen-reduction performance in microbial fuel cells
- 2023
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Ingår i: Journal of Power Sources. - : ELSEVIER. - 0378-7753 .- 1873-2755. ; 579
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Tidskriftsartikel (refereegranskat)abstract
- The metal-free carbon-based catalyst with low cost and high oxygen reduction reaction (ORR) activity is urgently desired to satisfy the demands of microbial fuel cells (MFCs). However, it is still a great challenge to develop a facile and feasible strategy to construct efficient active sites of heteroatom doping for carbon-based electrocatalyst. Herein, we report a strategy based on an ammonium fluoride (NH4F) gas-steamed metal-organic frameworks (MOFs) to heighten structural defects and density of N, F active sites of metal-free catalyst. Oxygen temperature-programmed deposition and density functional theory results confirm that the NH4F gas-steamed process greatly enhances the adsorption affinity of O2 and oxygen intermediates on the catalysts. The resulted N and F co-doped porous carbon cage (FNC-15) demonstrates outstanding ORR catalytic activity and long-term stability in alkaline and neutral electrolytes. This work proposes a facile and efficient in situ gas-steamed strategy to develop metal-free cathode catalysts with superior performance.
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