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Träfflista för sökning "WFRF:(Zhang Fang) srt2:(1998-1999)"

Sökning: WFRF:(Zhang Fang) > (1998-1999)

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Numrering	Referens	Omslagsbild	Hitta
1.	Dunham, I, et al. (författare) The DNA sequence of human chromosome 22 1999 Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 402:6761, s. 489-495 Tidskriftsartikel (refereegranskat)
2.	Fang, Hong, et al. (författare) Detection of imipenem-resistant and metronidazole-resistant Bacteroides fragilis group strains in fecal samples 1999 Ingår i: Clinical Microbiology and Infection. - : Elsevier BV. - 1198-743X .- 1469-0691. ; 5:12, s. 753-758 Tidskriftsartikel (refereegranskat)abstract Objective: To investigate the imipenem and metronidazole resistance profiles of Bacteroides fragilis group strains in fecal samples and to detect the resistance genes (ccrA and nim) coding for imipenem and metronidazole resistance in B. fragilis group strains. Methods: In total, 925 fecal samples, 729 from consecutive diarrhea patients and 196 from healthy controls, were collected at Huddinge University Hospital in 1997. A modified disk diffusion method was employed to screen for imipenem-resistant and metronidazole-resistant B. fragilis group strains. In strains considered resistant by the modified disk diffusion method, the minimum inhibitory concentrations (MICs) were further determined by the agar dilution method. PCR assays were used to detect the carbapenem-hydrolyzing metallo-P-lactamase gene (ccrA) and the 5-nitroimidazole resistance genes (nim) in pure cultures (purePCR), directly from fecal samples through direct broth enrichment (dirPCR) and by immunomagnetic separation (imsPCR). Results: Two imipenem-resistant B. fragilis strains, one of which was simultaneously resistant to metronidazole, and two B. fragilis group strains with MICs near the breakpoint for metronidazole resistance, were isolated from the fecal samples of diarrhea patients. The ccrA gene was identified in all the imipenem-resistant B. fragilis strains by purePCR, dirPCR and imsPCR. The nim genes were also detectable by these PCR assays. Conclusions: The incidences of imipenem-resistant and metronidazole-resistant B. fragilis group strains were low in the investigated diarrhea patients. Simultaneous resistance to imipenem and metronidazole is of great concern in clinical medicine, and the proposed PCR assays may be useful in epidemiologic studies of distribution of resistance genes in the fecal microflora.
3.	Huang, Fang, et al. (författare) Import and processing of nuclear-encoded mitochondrial proteins during development of pea plants : Plant Mitochondria from Gene to Function 1998 Konferensbidrag (refereegranskat)
4.	Iso, H, et al. (författare) Collaborative overview ('meta-analysis') of prospective observational studies of the associations of usual blood pressure and usual cholesterol levels with common causes of death: protocol for the second cycle of the Prospective Studies Collaboration 1999 Ingår i: Journal of cardiovascular risk. - : Oxford University Press (OUP). - 1350-6277 .- 1741-8267 .- 1741-8275. ; 6:5, s. 315-320 Tidskriftsartikel (refereegranskat)

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Resultat 1-4 av 4

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Typ av publikation: tidskriftsartikel (3); konferensbidrag (1)

Typ av innehåll: refereegranskat (4)

Författare/redaktör: Zhang, G (2); Beck, S (1); Chen, Y. (1); Li, S. (1); Williams, S. (1); Sasaki, T. (1); visa fler...; Wang, Y. (1); Nguyen, T. (1); Hall, C (1); Du, Z. (1); Nelson, J. (1); Williams, L. (1); Wang, Z. (1); Zhang, W. (1); Morris, J. (1); Lewis, J (1); Miller, N (1); Iso, H (1); Lewington, S (1); Shibuya, K (1); Chen, Z. (1); Shimizu, N. (1); Collins, R (1); Scheet, P (1); Sato, H. (1); Wang, Q. (1); Davies, C (1); Peto, R (1); CARSTENSEN, J (1); Fang, X. (1); Yao, Z. (1); Neaton, J (1); Dunham, I (1); Chen, F (1); Edlund, Charlotta (1); Cooper, J. (1); Whincup, P. (1); Hall, R (1); Ren, Q (1); Matthews, L (1); King, A (1); Tuomilehto, J. (1); Knekt, P (1); Johnson, D. (1); Clarke, R (1); Pearson, D. (1); Fang, F (1); Stampfer, M (1); Chu, L (1); Wu, H. (1); visa färre...

Lärosäte: Karolinska Institutet (2); Kungliga Tekniska Högskolan (1); Södertörns högskola (1)

Språk: Engelska (4)

Forskningsämne (UKÄ/SCB): Naturvetenskap (1); Lantbruksvetenskap (1)

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