| 1. |
- Ablikim, M., et al.
(författare)
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Measurements of (XcJ)-> K+K-K+K- decays
- 2006
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Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 642:3, s. 197-202
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Tidskriftsartikel (refereegranskat)abstract
- Using 14M psi(2S) events taken with the BESII detector, chi(cJ) -> 2(K+K-) decays are studied. For the four-kaon final state, the branching fractions are B(chi(c0,1,2) ->.2(K+K-)) = (3.48 +/- 0.23 +/- 0.47) x 10(-3), (0.70 +/- 0.13 +/- 0.10) x 10(-3), and (2.17 +/- 0.20 +/- 0.31) x 10(-3). For the phi K+K- final state, the branching fractions, which are measured for the first time, are B(chi(c0,1,2) -> phi K+K-) = (1.03 +/- 0.22 +/- 0.15) x 10(-3), (0.46 +/- 0.16 +/- 0.06) x 10(-3), and (1.67 +/- 0.26 +/- 0.24) x 10(-4). For the phi phi final state, B(chi(c0,2) -> phi phi) = (0.94 +/- 0.21 +/- 0.13) x 10(-3) and (1.70 +/- 0.30 +/- 0.25) x 10(-3).
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| 2. |
- Meng, Wen-Jian, et al.
(författare)
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Microsatellite instability did not predict individual survival in sporadic stage II and III rectal cancer patients
- 2007
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Ingår i: Oncology. - : S. Karger AG. - 0890-9091 .- 0030-2414 .- 1423-0232. ; 72:1-2, s. 82-88
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Tumors with high-frequency microsatellite instability (MSI-H) have unique biological behavior and the predictive role of microsatellite instability (MSI) status on survival of colorectal cancer is still debated. The prognostic significance of MSI status in sporadic stage II and III rectal cancer patients needs to be more precisely defined. So we investigated the relationship between MSI status and clinicopathological features and prognosis in these patients. Methods: DNAs from fresh-frozen paired samples of tumors and corresponding normal tissue from 128 stage II and III rectal cancer patients were analyzed for MSI by PCR amplification using markers recommended by a National Cancer Institute workshop on MSI. To assess prognostic significance, Cox proportional hazards modeling was used. Results: Twelve (9.3%) tumors in our study were MSI-H, 28 (21.9%) were low-frequency MSI (MSI-L) and 88 (68.8%) were microsatellite stable (MSS). Most of the MSI-H tumors compared with MSI-L and MSS tumors were found in female patients (p = 0.031), had mucinous histology (p = 0.023), high grade of differentiation (p = 0.002) and high level of preoperative serum carcinoembryonic antigen (p = 0.005). Rectal cancer patients with MSI-H did not show a better clinical outcome than those with MSI-L/MSS, neither in all cases (p = 0.986) nor in stage II and stage III disease analyzed separately (p = 0.705 and p = 0.664, respectively). Conclusions: Data provided here demonstrated there was high incidence of MSI-H and MSI was not a prognostic factor in sporadic stage II and III rectal cancers from the Chinese Han population included in this study. Tumor stage is more suitable than MSI status for prediction of individual survival in sporadic stage II and III rectal cancer patients. Copyright © 2007 S. Karger AG.
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| 3. |
- Meng, Wen-Jian, et al.
(författare)
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Novel mutations and sequence variants in exons 3-9 of human T Cell Factor-4 gene in sporadic rectal cancer patients stratified by microsatellite instability
- 2007
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Ingår i: World Journal of Gastroenterology. - 1007-9327 .- 2219-2840. ; 13:27, s. 3747-3751
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Tidskriftsartikel (refereegranskat)abstract
- Aim: To establish the role of human T Cell Factor-4 (hTCF-4) gene exons 3-9 mutation status in association with sporadic rectal cancer with microsatellite instability (MSI). Methods: Microsatellite markers were genotyped in 93 sporadic rectal cancer patients. Eleven cases were found to be high-frequency MSI (MSI-H). Sequence analysis of the coding region of the exons 3-9 of hTCF-4 gene was carried out for the 11 MSI-H cases and 10 controls (5 microsatellite stability (MSS) cases and 5 cases with normal mucosa). The sequencing and MSI identification were used. Results: Several novel mutations and variants were revealed. In exon 4, one is a 4-position continuous alteration which caused amino acid change from Q131T and S132I (391insA, 392 G > A, 393 A > G and 395delC) and another nucleotide deletion (395delC) is present in MSI-H cases (5/10 and 4/10, respectively) but completely absent in the controls. Conclusion: Novel mutations in exon 4 of hTCF-4 gene were revealed in this study, which might be of importance in the pathogenesis of sporadic rectal cancer patients with MSI-H. © 2007 WJG. All rights reserved.
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| 4. |
- Xu, Bing, et al.
(författare)
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Clinicopathological significance of caspase-8 and caspase-10 expression in rectal cancer
- 2008
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Ingår i: Oncology. - : S. Karger AG. - 0890-9091 .- 0030-2414 .- 1423-0232. ; 74:3-4, s. 229-236
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To investigate the expression of caspase-8 and -10 in rectal adenoma, adenocarcinoma and the corresponding normal mucosa tissue, and to clarify the relationship between their expression and clinicopathological parameters of rectal cancer. Methods: The expression of caspase-8 and -10 was determined by real-time RT-PCR and immunohistochemistry in 36 rectal adenomas, 93 rectal cancers and 93 corresponding normal rectal mucosa samples. Results: Compared with normal mucosa, the mRNA expression of caspase-8 was higher in adenomas (p = 0.003), while that of caspase-10 was lower in adenomas (p = 0.035) and cancers (p = 0.001). Immunohistochemical results showed caspase-8 up-regulation in adenomas (p = 0.014), and caspase-10 down-regulation in adenomas (p = 0.034) and cancers (p < 0.001) compared with normal mucosa samples. Cancers with poor differentiation had lower caspase-10 mRNA and protein levels than those with better differentiation (p = 0.041 and p = 0.046, respectively). The protein expression of caspase-8 and -10 was in accordance with the mRNA expression (p = 0.043 and p = 0.018, respectively). Conclusions: Caspase-8 expression was up-regulated in rectal adenomas. Caspase-10 expression was down-regulated in both rectal adenomas and cancers, and was further related to differentiation. Caspase-8 and -10 may be involved in the pathogenesis of rectal cancer. Copyright © 2008 S. Karger AG.
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| 5. |
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| 6. |
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| 7. |
- Chen, Jian, et al.
(författare)
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Sizing of MOS device in LC-tank oscillators
- 2007
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Ingår i: 2007 Norchip. - 9781424415168 ; , s. 90-95
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Konferensbidrag (refereegranskat)abstract
- Since previous publications show conflicting results about sizing device, relationship between device size and 1/f(2) phase noise is studied and closed-form equations are derived in order to help designers to size devices in LC-tank oscillators for good phase noise performance. The analysis is divided into two steps. Firstly, periodic noise transfer functions of each VCO noise source to the output of switch FETs are derived, and the impact of sizing on these functions is discussed. Secondly, phase noise equations are derived with these functions. Experiments show that phase noise predicted by the equations agrees with that from simulations.
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| 8. |
- Hamamoto-Kuroda, Ikuko, et al.
(författare)
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Weakly bound neutrons and quadrupole response function in the many-body pair correlation of neutron drip line nuclei
- 2006
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Ingår i: Journal of Physics G: Nuclear and Particle Physics. - : IOP Publishing. - 0954-3899 .- 1361-6471. ; 32:8, s. 1105-1119
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Tidskriftsartikel (refereegranskat)abstract
- A simplified model of the Hartree-Fock Bogoliubov (HFB) equation with surface-type or volume-type pairing is solved in coordinate space with the correct asymptotic boundary conditions. By using the resulting HFB wavefunctions, the low-energy quadrupole (L = 2) response function is studied for the system with weakly bound s and d neutrons. As the binding energy of the neutrons becomes small or approaches zero, the discrete solutions of the HFB equation disappear. Then, without any further correlation ( for example, random phase approximation ( RPA) correlation), the threshold quadrupole response becomes broader and moves toward very low excitation energies, while the total strength increases very rapidly. The important role of the continuum character of the upper component u(lj) (r) of the HFB s(1/2) wavefunction in the increasing strength is pointed out. The large and broad quadrupole response with a very low peak energy is expected for neutron drip line nuclei with N approximate to 56 and Z approximate to 28, of which both the neutron 2d(5/2) and 3s(1/2) orbits may be weakly bound in the Hartree-Fock (HF) potential.
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| 9. |
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| 10. |
- She, Huimin, et al.
(författare)
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Analytical Evaluation of Retransmission Schemes in Wireless Sensor Networks
- 2009
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Ingår i: 2009 IEEE VEHICULAR TECHNOLOGY CONFERENCE. - 9781424425167 ; , s. 38-42
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Konferensbidrag (refereegranskat)abstract
- Retransmission has been adopted as one of the most popular schemes for improving transmission reliability in wireless sensor networks. Many previous works have been done on reliable transmission issues in experimental ways, however, there still lack of analytical techniques to evaluate these solutions. Based on the traffic model, service model and energy model, we propose an analytical method to analyze the delay and energy metrics of two categories of retransmission schemes: hop-by-hop retransmission (HBH) and end-to-end retransmission (ETE). With the experiment results, the maximum packet transfer delay and energy efficiency of these two scheme are compared in several scenarios. Moreover, the analytical results of transfer delay are validated through simulations. Our experiments demonstrate that HBH has less energy consumption at the cost of lager transfer delay compared with ETE. With the same target success probability, ETE is superior on the delay metric for low bit-error-rate (BER) cases, while HBH is superior for high BER cases.
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| 11. |
- She, Huimin, et al.
(författare)
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Traffic splitting with network calculus for mesh sensor networks
- 2007
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Ingår i: Proceedings of Future Generation Communication and Networking, FGCN 2007. - : IEEE Computer Society. - 9780769530482 ; , s. 371-376
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Konferensbidrag (refereegranskat)abstract
- In many applications of sensor networks, it is essential to ensure that messages are transmitted to their destinations as early as possible and the buffer size of each sensor node is as small as possible. In this paper, we firstly propose a mesh sensor network system model. Based on this system model, the expressions for deriving the delay bound and buffer requirement bound are presented using network calculus. In order to balance traffic load and improve resource utilization, three traffic splitting mechanisms are proposed The numerical results show that the delay bound and buffer requirement bound are lowered while applying those traffic splitting mechanisms. And thus the performance of the whole sensor network is improved.
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| 12. |
- Wang, Peng, et al.
(författare)
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Low Noise Amplifier Architecture Analysis for UWB System
- 2008
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Ingår i: 2008 INTERNATIONAL SYMPOSIUM ON SYSTEM-ON-CHIP, PROCEEDINGS. - NEW YORK : IEEE. ; , s. 53-56
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Konferensbidrag (refereegranskat)abstract
- This paper analyzes the architecture of wideband low noise amplifier (LNA) for multi-band orthogonal frequency division multiplexing modulation (MB-OFDM) ultra-wideband (UWB) system. Noise matching and input impedance matching are compared among different LNA architectures. Power consumption and area for different kinds of LNA architectures are also compared through the figure of merit (FOM).
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| 13. |
- Wang, Peng, et al.
(författare)
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PER Performance Enhancement through Antenna And Transceiver Co-Design for Multi-band OFDM UWB Communication
- 2008
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Ingår i: 2008 INTERNATIONAL SYMPOSIUM ON SYSTEM-ON-CHIP, PROCEEDINGS. - NEW YORK : IEEE. - 9781424425419 ; , s. 142-146
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Konferensbidrag (refereegranskat)abstract
- This paper investigates the packet error rate (PER) performance enhancement through the antenna and the transceiver co-design for MB-OFDM UWB system. Five different UWB antennas, covering the whole UWB spectrum, are selected for study. Through the link-margin analysis and PER performance simulation, radio transceiver design specifications are optimized according to different antennas' performance at different band groups. Transmitter pre-distortion and receiver equalization are applied at the front-end of the transceiver to co-design with the antenna, which further enhance PER performance. Our study reveals that, antenna is an important part of radio transceiver which has to be considered in advance during the chip design [1], particularly in the ultra-wide band radio system. Through the antenna and radio front-end co-design, not only could PER performance be enhanced, but also could design parameters be relaxed for the power amplifier (PA) and the low noise amplifier (LNA), particularly for higher band groups.
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| 14. |
- Wang, Yong, et al.
(författare)
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mRNA expression of minichromosome maintenance 2 in colonic adenoma and adenocarcinoma
- 2009
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Ingår i: EUROPEAN JOURNAL OF CANCER PREVENTION. - 0959-8278. ; 18:1, s. 40-45
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Tidskriftsartikel (refereegranskat)abstract
- As proliferation is essential for Progression from normal cells to tumor, certain markers specific to proliferating cells may permit detection of premalignant lesions. Here, we aimed to evaluate the possible value of a proliferation marker, minichromosome maintenance 2 (MCM2), in the early diagnosis of colorectal cancer, by analyzing the difference in MCM2 expression among normal mucosa, adenoma, and adenocarcinoma, and investigating the relationship of MCM2 expression in adenomas with clinicopathologic variables. Using immunohistochemistry and real-time reverse transcription-PCR, we observed that the expression of MCM2 protein was present on basal third to half of colonic crypts in normal mucosa, whereas throughout the epithelium in adenomas and adenocarcinomas, the expression of MCM2 mRNA in adenocarcinomas was significantly higher than in adenomas (P=0.001), whereas the difference between adenoma and normal mucosa was not significant (P=0.184); we also found that the expression of MCM2 mRNA tended to be increased in the adenomas with high-grade dysplasia, or in older patients, respectively, compared with those with low-grade dysplasia, and younger patients. These results suggested the potential value of MCM2 in early diagnosis of colorectal cancer.
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