| 1. |
- Kaldo, Viktor, et al.
(författare)
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Internetbaserad självhjälpsbehandling mot tinnitusbesvär
- 2004
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Ingår i: Svenska läkartidningen. - 0371-439X. ; 101, s. 556--560
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Tidskriftsartikel (refereegranskat)abstract
- Tinnitusbesvär kan minskas med kognitiv beteendeterapi. Självhjälpsbehandling, ofta med viss terapeutkontakt, kan öka tillgången på denna terapiform. Medicinskt färdigutredda patienter vid audiologiska avdelningen på Akademiska sjukhuset i Uppsala har sedan 1999 kunnat genomgå kognitiv beteendeterapi mot tinnitusbesvär i grupp, individuellt eller som Internetbaserad självhjälpsbehandling. Självhjälpsbehandlingen utgår från en webbplats och består av s k verktyg. En träningsvecka omfattar val av verktyg, information, instruktioner, planering av verktygens användning samt träning som registreras. Terapeuten följer patientens behandling och ger återkoppling via e-post. Stor vikt läggs vid att hålla kontinuerlig kontakt med patienten under behandlingen.Internetbehandlingens effekt har prövats i en kontrollerad studie, i en klinisk replikation samt i en direkt jämförelse med vanlig kognitiv beteendeterapi i gruppform. Resultaten har varit goda och jämförbara med ordinarie behandling.
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| 2. |
- Nilsson-Ihrfelt, Elisabeth, et al.
(författare)
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Autobiographical memories in patients treated for breast cancer
- 2004
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Ingår i: Journal of Psychosomatic Research. - : Elsevier BV. - 0022-3999 .- 1879-1360. ; 57:4, s. 363-366
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Tidskriftsartikel (refereegranskat)abstract
- Objective Previous research has shown that several clinical groups have difficulties with generating specific autobiographical memories. The aim of this study was to investigate autobiographical memory function in women who had been treated for breast cancer and to compare those patients who had undergone mastectomy only with those who had undergone breast reconstruction surgery after mastectomy. Method A sample of 26 women treated for breast cancer were tested via telephone using the Autobiographical Memory Test (AMT). Results Breast cancer patients had difficulty retrieving specific autobiographical memories compared to a group of age-matched controls without any history of breast cancer. There were essentially no differences between the two patient groups. Conclusion Since breast cancer patients are vulnerable to emotional distress, autobiographical memory deficits should be investigated further. © 2004 Elsevier Inc. All rights reserved.
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| 3. |
- Westergaard, David, et al.
(författare)
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Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage.
- 2024
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Ingår i: Nature genetics. - 1546-1718.
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Tidskriftsartikel (refereegranskat)abstract
- Bleeding in early pregnancy and postpartum hemorrhage (PPH) bear substantial risks, with the former closely associated with pregnancy loss and the latter being the foremost cause of maternal death, underscoring the severe impact on maternal-fetal health. We identified five genetic loci linked to PPH in a meta-analysis. Functional annotation analysis indicated candidate genes HAND2, TBX3 and RAP2C/FRMD7 at three loci and showed that at each locus, associated variants were located within binding sites for progesterone receptors. There were strong genetic correlations with birth weight, gestational duration and uterine fibroids. Bleeding in early pregnancy yielded no genome-wide association signals but showed strong genetic correlation with various human traits, suggesting a potentially complex, polygenic etiology. Our results suggest that PPH is related to progesterone signaling dysregulation, whereas early bleeding is a complex trait associated with underlying health and possibly socioeconomic status and may include genetic factors that have not yet been identified.
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