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1.	Hartman, Henrik, et al. (author) Negative ion relaxation and reactions in a cryogenic storage ring 2020 In: Journal of Physics: Conference Series Vol 1412. - : IOP Publishing. - 1742-6588 .- 1742-6596. Conference paper (peer-reviewed)abstract An overview of recent experimental results of studies of negative atomic and molecular ions in the Double ElectroStatic Ion-Ring ExpEriment, DESIREE is given. Metastable level lifetimes in atomic negative ions have been measured by time-dependent laser photodetachment. Rotational relaxation of diatomic anions is studied by near-threshold photodetachment. Spontaneous decays of small metal cluster anions by electron emission and fragmentation is studied with decay-channel specificity. Finally, mutual neutralisation of pairs of negative and positive ions has been investigated with initial and final state selectivity.
2.	Coenen, M, et al. (author) GENOME-WIDE ASSOCIATION ANALYSIS OF PAIN REDUCTION IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH TNF INHIBITORS 2014 In: ANNALS OF THE RHEUMATIC DISEASES. - : BMJ. - 0003-4967 .- 1468-2060. ; 73, s. 348-348 Conference paper (other academic/artistic)
3.	Coenen, MJH, et al. (author) Genome-Wide Association Analysis of Pain Reduction in Rheumatoid Arthritis Patients Treated with TNF Inhibitors. 2014 In: ARTHRITIS & RHEUMATOLOGY. - 2326-5191. ; 66, s. S1296-S1296 Conference paper (other academic/artistic)
4.	Fritzell, S, et al. (author) Income-related inequalities in mental health in Sweden and the role of social determinants 2019 In: EUROPEAN JOURNAL OF PUBLIC HEALTH. - 1101-1262. ; 29, s. 233-233 Conference paper (other academic/artistic)
5.	Jiang, X, et al. (author) ANTI-CARP ANTIBODIES IN TWO LARGE COHORTS OF PATIENTS WITH RHEUMATOID ARTHRITIS AND THEIR RELATIONSHIP TO GENETIC RISK FACTORS AND SMOKING 2014 In: ANNALS OF THE RHEUMATIC DISEASES. - : BMJ. - 0003-4967 .- 1468-2060. ; 73, s. A11-A12 Conference paper (other academic/artistic)
6.	Jiang, X, et al. (author) Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies 2014 In: Annals of the rheumatic diseases. - : BMJ. - 1468-2060 .- 0003-4967. ; 73:10, s. 1761-1768 Journal article (peer-reviewed)
7.	Jiang, X, et al. (author) ANTI-CARP ANTIBODIES IN TWO LARGE COHORTS OF PATIENTS WITH RHEUMATOID ARTHRITIS AND THEIR RELATIONSHIP TO GENETIC RISK FACTORS, CIGARETTE SMOKING AND OTHER AUTOANTIBODIES 2014 In: ANNALS OF THE RHEUMATIC DISEASES. - : BMJ. - 0003-4967 .- 1468-2060. ; 73, s. 510-511 Conference paper (other academic/artistic)
8.	Lundberg, K, et al. (author) CITRULLINATED alpha-ENOLASE: A MAJOR AUTOANTIGEN LINKING SMOKING AND HLA-DRB1 SHARED EPITOPE TO RHEUMATOID ARTHRITIS 2009 In: RHEUMATOLOGY. - 1462-0324. ; 48, s. I1-I1 Conference paper (other academic/artistic)
9.	Lundberg, K, et al. (author) Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis Reply 2010 In: NATURE GENETICS. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 42:10, s. 816-816 Journal article (other academic/artistic)
10.	Olsson, Lina, et al. (author) A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity 2007 In: Arthritis Research and Therapy. - : Springer Science and Business Media LLC. - 1478-6362 .- 1478-6354. ; 9:5 Journal article (peer-reviewed)abstract ABSTRACT: Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed. By studying animal models, reduced capacity of the NADPH-oxidase (NOX) complex, caused by a single nucleotide polymorphism (SNP) in one of its components (the NCF1 gene), has been found to increase severity of arthritis. To our knowledge, however, no studies investigating the potential role played by reduced reactive oxygen species production in human RA have yet been reported. In order to examine the role played by the NOX complex in RA, we investigated the association of 51 SNPs in five genes of the NOX complex (CYBB, CYBA, NCF4, NCF2, and RAC2) in a Swedish case-control cohort consisting of 1,842 RA cases and 1,038 control individuals. Several SNPs were found to be mildly associated in men in NCF4 (rs729749, P = 0.001), NCF2 (rs789181, P = 0.02) and RAC2 (rs1476002, P = 0.05). No associations were detected in CYBA or CYBB. By stratifying for autoantibody status, we identified a strong association for rs729749 (in NCF4) in autoantibody negative disease, with the strongest association detected in rheumatoid factor negative men (CT genotype versus CC genotype: odds ratio 0.34, 95% confidence interval 0.2 to 0.6; P = 0.0001). To our knowledge, this is the first genetic association identified between RA and the NOX complex, and it supports previous findings from animal models of the importance of reactive oxygen species production capacity to the development of arthritis.

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Type of publication: journal article (48); conference paper (35); research review (1)

Type of content: peer-reviewed (43); other academic/artistic (41)

Author/Editor: Kallberg, H (68); Alfredsson, L (48); KLARESKOG, L (46); Padyukov, L (26); Bengtsson, C (18); Jiang, X. (12); show more...; Saevarsdottir, S (8); Frisell, T (7); Jornvall, H (6); Lundberg, I (6); Ronnelid, J (6); Ding, B. (6); Plenge, RM (6); Persson, B (5); Malmstrom, V (4); Ahlbom, A (4); Martin, J. (3); Danared, H. (3); Shi, J. (3); Gonzalez-Gay, MA (3); Feychting, M (3); Larsson, M (3); Hanstorp, Dag, 1960 (3); de Faire, U (3); Huizinga, TWJ (3); Gigante, B (3); Leander, K (3); Israelsson, L (3); van der Woude, D. (3); Thomas, R D (3); Hellberg, F (2); Tegner, Yelverton (2); Wijmenga, C (2); Gregersen, PK (2); van Riel, PLCM (2); Ophoff, RA (2); Lie, BA (2); Koeleman, BPC (2); Moreno, I (2); Criswell, LA (2); Mariette, X (2); Pegg, D. J. (2); van der Helm-van Mil ... (2); Huizinga, T (2); De Vries, N (2); Österdahl, Fabian (2); Sjogren, B (2); Sjolander, A (2); Pawitan, Y (2); Fritioff, K. (2); show less...

University: Karolinska Institutet (75); University of Gothenburg (6); Uppsala University (3); Royal Institute of Technology (2); Luleå University of Technology (2); Stockholm University (2); show more...; Lund University (2); Chalmers University of Technology (2); Umeå University (1); Linköping University (1); Malmö University (1); RISE (1); show less...

Language: English (84)

Research subject (UKÄ/SCB): Medical and Health Sciences (8); Natural sciences (5)

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