| 1. |
- Contessotto, P., et al.
(författare)
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Elastin-like recombinamers-based hydrogel modulates post-ischemic remodeling in a non-transmural myocardial infarction in sheep
- 2021
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Ingår i: Science Translational Medicine. - : American Association for the Advancement of Science (AAAS). - 1946-6234 .- 1946-6242. ; 13:581
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Tidskriftsartikel (refereegranskat)abstract
- Ischemic heart disease is a leading cause of mortality due to irreversible damage to cardiac muscle. Inspired by the post-ischemic microenvironment, we devised an extracellular matrix (ECM)-mimicking hydrogel using catalyst-free click chemistry covalent bonding between two elastin-like recombinamers (ELRs). The resulting customized hydrogel included functional domains for cell adhesion and protease cleavage sites, sensitive to cleavage by matrix metalloproteases overexpressed after myocardial infarction (MI). The scaffold permitted stromal cell invasion and endothelial cell sprouting in vitro. The incidence of non-transmural infarcts has increased clinically over the past decade, and there is currently no treatment preventing further functional deterioration in the infarcted areas. Here, we have developed a clinically relevant ovine model of non-transmural infarcts induced by multiple suture ligations. Intramyocardial injections of the degradable ELRs-hydrogel led to complete functional recovery of ejection fraction 21 days after the intervention. We observed less fibrosis and more angiogenesis in the ELRs-hydrogel-treated ischemic core region compared to the untreated animals, as validated by the expression, proteomic, glycomic, and histological analyses. These findings were accompanied by enhanced preservation of GATA4(+) cardiomyocytes in the border zone of the infarct. We propose that our customized ECM favors cardiomyocyte preservation in the border zone by modulating the ischemic core and a marked functional recovery. The functional benefits obtained by the timely injection of the ELRs-hydrogel in a clinically relevant MI model support the potential utility of this treatment for further clinical translation.
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| 2. |
- Shtepliuk, Ivan, et al.
(författare)
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Probing the uniformity of silver-doped epitaxial graphene by micro-Raman mapping
- 2020
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Ingår i: Physica. B, Condensed matter. - : ELSEVIER. - 0921-4526 .- 1873-2135. ; 580
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Tidskriftsartikel (refereegranskat)abstract
- We present a Raman spectroscopy study on epitaxial graphene decorated with thin Ag films (2-15 nm), which are deposited using magnetron sputtering. We find that the presence of Ag on the graphene surface induces doping, the uniformity and efficiency of which is determined by Ag nominal thickness. Deposition of Ag films with thicknesses up to 5 nm favors the effective electron transfer from Ag to epitaxial graphene. A significant redshift and broadening of the 2D peak are observed with increasing the Ag-layer thickness above 5 nm, which is indicative of large strain and doping fluctuations. We also observe a non-trivial linear growth of 2D/G peak intensity ratio with increasing D/G ratio for all Ag-decorated samples, which is explained by increase of peak amplitude due to surface enhanced Raman scattering and charged impurity-induced screening caused by the presence of Ag on the graphene surface.
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| 3. |
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| 4. |
- Wang, Zhaohui, et al.
(författare)
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Conducting Polymer Paper-Based Cathodes for High-Areal-Capacity Lithium–Organic Batteries
- 2015
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Ingår i: Energy Technology. - : Wiley. - 2194-4296 .- 2194-4288. ; 3:6, s. 563-569
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Tidskriftsartikel (refereegranskat)abstract
- Conducting polymers have been considered for use as cathode materials in rechargeable lithium‐ion batteries (LIBs) since 1981 but problems with poor cycling stability, rapid self‐discharge, and low energy and power densities have so far limited their applicability. Herein it is shown that nanostructured freestanding conducting polymer composites [e.g., polypyrrole (PPy) and polyaniline (PANI)] can be used to circumvent these shortcomings. Freestanding and binder‐free PPy and cellulose‐based composites can straightforwardly be used as versatile organic cathode materials for LIBs. The composite, reinforced with chopped carbon filaments (CCFs), exhibited a large active mass loading of approximately 10 mg cm−2, an areal capacity of 1.0 mAh cm−2 (corresponding to 102 mAh g−1), and stable cycling. With an active mass loading of 4.4 mg cm−2, a capacity of 0.22 mAh cm−2 (corresponding to 58 mAh g−1) was found for current densities of 5 A g−1 yielding discharge times of approximately 40 seconds, and a capacity retention of 91 % over 100 cycles was obtained at 0.2 A g−1. The present method constitutes a straightforward approach for the manufacturing of high‐performance freestanding electroactive conducting‐polymer‐based paper‐like electrodes for use in inexpensive and sustainable, high‐performance organic LIBs.
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| 5. |
- Couceiro, José, 1983-, et al.
(författare)
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In situ CT-scanning for detection of internal checking and cell collapse during drying of hardwood species
- 2016
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Ingår i: The 7th European Conference on Hardwood, Eco-efficient resource wood with special focus on hardwoods. - Sopron : University of West Hungary. - 9789633342916 ; , s. 58-59
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Konferensbidrag (refereegranskat)abstract
- During the drying of sawn timber, hydrostatic tension forces within the cell may exceed the compressive strength perpendicular to the grain of the thin cell wall and the cell then collapses. This phenomenon is common in hardwoods such as Sequoia sempervirens, Thuja plicata, Tsuga heterophylla, Juglans nigraand many species of eucalyptus and oak. Usually, this leads to severe surface deformation, and both surface and internal checking(honeycombing) may occur. The quality of the final product is lowered by these cracks and deformations. The aim of this study was to investigate, by CT-scanning samples throughout the drying process, whether it is possible to detect when and how cracking and deformation occurs and develops in specimens of Eucalyptus nitens. Based on this knowledge, better drying schedules can be developed to improve the yield and ensure a higher quality of the sawn timber. Three specimens, one specimen in each drying run, of Eucalyptus nitens were used for the tests. Their cross-sectional dimensions, prior to drying, were 105x23 mm2 and their length was 70 cm. A specially designed laboratory drying kiln that fits within the gantry of a Siemens Somatom Emotion medical CT-scanner was used (Fig. 1). With this equipment, it is possible to scan the inside of the kiln without interrupting the drying process.
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| 6. |
- Haileselassie, Yeneneh, et al.
(författare)
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Lactobacillus reuteri and Staphylococcus aureus differentially influence the generation of monocyte-derived dendritic cells and subsequent autologous T cell responses
- 2016
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Ingår i: Immunity, Inflammation and Disease. - : Wiley. - 2050-4527. ; 4:3, s. 315-326
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: In early-life, the immature mucosal barrier allows contact between the gut microbiota and the developing immune system. Due to their strategic location and their ability to sample luminal antigen, dendritic cells (DC) play a central role in the interaction of microbes and immune cells in the gut. Here, we investigated how two bacteria associated with opposite immune profiles in children, that is, Lactobacillus (L.) reuteri and Staphylococcus (S.) aureus, influenced the differentiation of monocytes in vitro as well how the generated DC impacted T cell responses.Methods: We exposed monocyte cultures to cell-free supernatants (CFS) from these bacteria during their differentiation to DC.Results: The presence of L. reuteri-CFS during DC differentiation resulted in DC with a more mature phenotype, in terms of up-regulated surface markers (HLA-DR, CD86, CD83, CCR7) and enhanced cytokine production (IL6, IL10, and IL23), but had a reduced phagocytic capacity compared with non-treated monocyte-derived DC (Mo-DC). However, upon LPS activation, L. reuteri-CFS-generated DC displayed a more regulated phenotype than control Mo-DC with notable reduction of cytokine responses both at mRNA and protein levels. In contrast, S. aureus-CFS-generated DC were more similar to control Mo-DC both without and after LPS stimulation, but they were still able to induce responses in autologous T cells, in the absence of further T cell stimulation.Conclusions: We show that bacterial signals during DC differentiation have a profound impact on DC function and possibly also for shaping the T cell pool.
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| 7. |
- Maurotti, S., et al.
(författare)
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Hemp Seeds in Post-Arthroplasty Rehabilitation: A Pilot Clinical Study and an In Vitro Investigation
- 2021
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Ingår i: Nutrients. - : MDPI AG. - 2072-6643. ; 13:12
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Tidskriftsartikel (refereegranskat)abstract
- Osteoarthritis is a type of degenerative joint disease that results from the breakdown of joint cartilage and underlying bone. Due to their antioxidants and anti-inflammatory action, the phytochemical constituents of many vegetable varieties could represent a new frontier for the treatment of patients with Osteoarthritis and are still being explored. The aim of this pilot human study was to investigate the effects of pasta enriched with hemp seed flour on osteoarticular pain and bone formation markers in patients in post-arthroplasty rehabilitation. Another purpose was to evaluate the effect of hemp seed extract on bone metabolism, in vitro. A pilot, controlled, clinical study was conducted to verify the feasibility of pain symptom reduction in patients with Osteoarthritis undergoing arthroplasty surgery. We also investigated the effect of hemp seed extract on the Wnt/beta-catenin and ERK1/2 pathways, alkaline phosphatase, RANKL, RUNX-2, osteocalcin, and COL1A on Saos-2. After 6 weeks, the consumption of hemp seed pasta led to greater pain relief compared to the regular pasta control group (-2.9 +/- 1.3 cm vs. -1.3 +/- 1.3 cm; p = 0.02). A significant reduction in serum BALP was observed in the participants consuming the hemp seed pasta compared to control group (-2.8 +/- 3.2 mu g/L vs. 1.1 +/- 4.3 mu g/L; p = 0.04). In the Saos-2 cell line, hemp seed extract also upregulated Wnt/beta-catenin and Erk1/2 pathways (p = 0.02 and p = 0.03) and osteoblast differentiation markers (e.g., ALP, OC, RUNX2, and COL1A) and downregulated RANKL (p = 0.02), compared to the control. Our study demonstrated that hemp seed can improve pain symptoms in patients with osteoarthritis undergoing arthroplasty surgery and also improves bone metabolism both in humans and in vitro. However, more clinical studies are needed to confirm our preliminary findings.
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| 8. |
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| 9. |
- Camnitzer, Gabo
(författare)
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Frontier Vernacular
- 2014
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Ingår i: Raja Gallery in Tallinn, Estonia.
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Konstnärligt arbete (övrigt vetenskapligt/konstnärligt)abstract
- An exhibition of work by Gabo Camnitzer.
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| 10. |
- Ekman, Torbjörn
(författare)
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Rewritable Reference Attributed Grammars - design, implementation, and applications
- 2004
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis presents an object-oriented technique for rewriting abstract syntax trees in order to simplify compilation. The technique, Rewritable Reference Attributed Grammars (ReRAGs), is completely declarative and supports both rewrites and computations by means of attributes. We have implemented ReRAGs in our aspect-oriented compiler compiler tool JastAdd II. We present the ReRAG formalism, its evaluation algorithm, and examples of its use. JastAdd II uses three synergistic mechanisms for supporting separation of concerns: inheritance for model modularization, aspects for cross-cutting concerns, and rewrites that allow computations to be expressed on the most suitable model. This allows compilers to be written in a high-level declarative and modular fashion, supporting language extensibility as well as reuse of modules for different compiler-related tools. Each technique is presented using a series of simplified examples from static semantic analysis for the Java programming language. A case study is presented where ReRAGs are used extensively to implement a compiler for the Control Module extension to the IEC61131-3 automation languages. That Control Modules concept is further extended, in a modular fashion, with object-oriented features to improve encapsulation, composition mechanisms, code re-use, and type safety.
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| 11. |
- Ewins, Kristin
(författare)
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The Pilgrims : by Mary Shelley
- 2008
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Ingår i: TLS - The Times Literary Supplement. - 0307-661X .- 1366-7211. ; :November 28
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Recension (populärvet., debatt m.m.)
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| 12. |
- Feng, Chen, et al.
(författare)
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Predicting and mapping neighborhood-scale health outcomes : A machine learning approach
- 2021
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Ingår i: Computers, Environment and Urban Systems. - : Elsevier BV. - 0198-9715. ; 85
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Tidskriftsartikel (refereegranskat)abstract
- Estimating health outcomes at a neighborhood scale is important for promoting urban health, yet costly and time-consuming. In this paper, we present a machine-learning-enabled approach to predicting the prevalence of six common non-communicable chronic diseases at the census tract level. We apply our approach to the City of Austin and show that our method can yield fairly accurate predictions. In searching for the best predictive models, we experiment with eight different machine learning algorithms and 60 predictor variables that characterize the social environment, the physical environment, and the aspects and degrees of neighborhood disorder. Our analysis suggests that (a) the sociodemographic and socioeconomic variables are the strongest predictors for tract-level health outcomes and (b) the historical records of 311 service requests can be a useful complementary data source as the information distilled from the 311 data often helps improve the models' performance. The machine learning models yielded from this study can help the public and city officials evaluate future scenarios and understand how changes in the neighborhood conditions can lead to changes in the health outcomes. By analyzing where the most significant discrepancies between the predicted and the actual values are, we will also be ready to identify areas of best practice and areas in need of greater investment or policy intervention.
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| 13. |
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| 14. |
- Figueredo, CM, et al.
(författare)
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T and B Cells in Periodontal Disease: New Functions in A Complex Scenario
- 2019
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Ingår i: International journal of molecular sciences. - : MDPI AG. - 1422-0067. ; 20:16
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Tidskriftsartikel (refereegranskat)abstract
- Periodontal disease is characterised by a dense inflammatory infiltrate in the connective tissue. When the resolution is not achieved, the activation of T and B cells is crucial in controlling chronic inflammation through constitutive cytokine secretion and modulation of osteoclastogenesis. The present narrative review aims to overview the recent findings of the importance of T and B cell subsets, as well as their cytokine expression, in the pathogenesis of the periodontal disease. T regulatory (Treg), CD8+ T, and tissue-resident γδ T cells are important to the maintenance of gingival homeostasis. In inflamed gingiva, however, the secretion of IL-17 and secreted osteoclastogenic factor of activated T cells (SOFAT) by activated T cells is crucial to induce osteoclastogenesis via RANKL activation. Moreover, the capacity of mucosal-associated invariant T cells (MAIT cells) to produce cytokines, such as IFN-γ, TNF-α, and IL-17, might indicate a critical role of such cells in the disease pathogenesis. Regarding B cells, low levels of memory B cells in clinically healthy periodontium seem to be important to avoid bone loss due to the subclinical inflammation that occurs. On the other hand, they can exacerbate alveolar bone loss in a receptor activator of nuclear factor kappa-B ligand (RANKL)-dependent manner and affect the severity of periodontitis. In conclusion, several new functions have been discovered and added to the complex knowledge about T and B cells, such as possible new functions for Tregs, the role of SOFAT, and MAIT cells, as well as B cells activating RANKL. The activation of distinct T and B cell subtypes is decisive in defining whether the inflammatory lesion will stabilise as chronic gingivitis or will progress to a tissue destructive periodontitis.
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| 15. |
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| 16. |
- Fu, Y, et al.
(författare)
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Electron wave-packet transport through nanoscale semiconductor device in time domain
- 2005
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Ingår i: Journal of Applied Physics. - : American Institute of Physics. - 0021-8979 .- 1089-7550. ; 97:9
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Tidskriftsartikel (refereegranskat)abstract
- Future low-power downscaled metal-oxide-semiconductor (MOS) devices are in a size regime that requires a quantum-mechanical approach. Two theoretical approaches, the steady-state single plane-wave transport model and the time-dependent wave-packet transport model, have been discussed to study the electron transport through model nanoscale potential profiles. It has been shown that the single plane-wave transport model at steady state neglects the coupling among different plane waves induced by the potential profile variation induced by the external bias. Thus, the model is only valid when the external bias is rather small. The electron wave-packet transport theory models the electrons by wave packets consisting of all available plane waves in the contact from where the electrons originate. The couplings among different plane waves are included in the temporal evolution of the time-dependent Schrodinger equation. This model is thus more proper when studying nanoscale devices at normal device working configurations. The effects of gate bias and the device geometry on the wave-packet transport are then studied by model potentials of future downscaled devices, which explains the experimentally reported conventional I-V characteristics of nanoscale MOS field-effect transistors (MOSFETs) at room temperature, while the normal MOSFET functioning is expected to be impossible by the single plane-wave transport model due to the independent tunneling effects of individual plane waves.
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| 17. |
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| 18. |
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| 19. |
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| 20. |
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| 21. |
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| 22. |
- Markström, Jonas L., 1985-, et al.
(författare)
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ACL-reconstructed and ACL-deficient individuals show differentiated trunk, hip, and knee kinematics during vertical hops more than 20 years post-injury
- 2018
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Ingår i: Knee Surgery, Sports Traumatology, Arthroscopy. - : Springer Science and Business Media LLC. - 0942-2056 .- 1433-7347. ; 26:2, s. 358-367
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: Little is known regarding movement strategies in the long term following injury of the anterior cruciate ligament (ACL), and even less about comparisons of reconstructed and deficient knees in relation to healthy controls. The present purpose was to compare trunk, hip, and knee kinematics during a one-leg vertical hop (VH) ~20 years post-ACL injury between persons treated with surgery and physiotherapy (ACLR), solely physiotherapy (ACLPT), and controls (CTRL). Between-leg kinematic differences within groups were also investigated.METHODS: Sixty-six persons who suffered unilateral ACL injury on average 23 ± 2 years ago (32 ACLR, 34 ACLPT) and 33 controls performed the VH. Peak trunk, hip, and knee angles during Take-off and Landing phases recorded with a 3D motion capture system were analysed with multivariate statistics.RESULTS: Significant group effects during both Take-off and Landing were found, with ACLPT differing from CTRL in Take-off with a combination of less knee flexion and knee internal rotation, and from both ACLR and CTRL in Landing with less hip and knee flexion, knee internal rotation, and greater hip adduction. ACLR also presented different kinematics to ACLPT and CTRL in Take-off with a combination of greater trunk flexion, hip flexion, hip internal rotation, and less knee abduction, and in Landing with greater trunk flexion and hip internal rotation. Further, different kinematics and hop height were found between legs within groups in both Take-off and Landing for both ACL groups, but not for CTRL.CONCLUSION: Different kinematics for the injured leg for both ACL groups compared to CTRL and between treatment groups, as well as between legs within treatment groups, indicate long-term consequences of injury. Compensatory mechanisms for knee protection seem to prevail over time irrespective of initial treatment, possibly increasing the risk of re-injury and triggering the development of osteoarthritis. Detailed investigation of movement strategies during the VH provides important information and a more comprehensive evaluation of knee function than merely hop height. More attention should also be given to the trunk and hip in clinics when evaluating movement strategies after ACL injury.LEVEL OF EVIDENCE: Prospective cohort study, Level II.
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| 23. |
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| 24. |
- Risuleo, Riccardo Sven, 1986-, et al.
(författare)
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A nonparametric kernel-based approach to Hammerstein system identification
- 2017
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Ingår i: Automatica. - : Elsevier BV. - 0005-1098 .- 1873-2836. ; 85, s. 234-247
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Tidskriftsartikel (refereegranskat)abstract
- Hammerstein systems are the series composition of a static nonlinear function and a linear dynamic system, In this work, we propose a nonparametric method for the identification of Hammerstein systems. We adopt a kernel-based approach to model the two components of the system. In particular, we model the nonlinear function and the impulse response of the linear block as Gaussian processes with suitable kernels. The kernels can be chosen to encode prior information about the nonlinear function and the system. Following the empirical Bayes approach, we estimate the posterior mean of the impulse response using estimates of the nonlinear function, of the hyperparameters, and of the noise variance. These estimates are found by maximizing the marginal likelihood of the data. This maximization problem is solved using an iterative scheme based on the expectation-conditional maximization, which is a variation of the standard expectation maximization method for solving maximum-likelihood problems. We show the effectiveness of the proposed identification scheme in some simulation experiments.
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| 25. |
- Schulz, Robert, et al.
(författare)
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Is the future of peer review automated?
- 2022
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Ingår i: BMC Research Notes. - : Springer Nature. - 1756-0500. ; 15:1
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The rising rate of preprints and publications, combined with persistent inadequate reporting practices and problems with study design and execution, have strained the traditional peer review system. Automated screening tools could potentially enhance peer review by helping authors, journal editors, and reviewers to identify beneficial practices and common problems in preprints or submitted manuscripts. Tools can screen many papers quickly, and may be particularly helpful in assessing compliance with journal policies and with straightforward items in reporting guidelines. However, existing tools cannot understand or interpret the paper in the context of the scientific literature. Tools cannot yet determine whether the methods used are suitable to answer the research question, or whether the data support the authors' conclusions. Editors and peer reviewers are essential for assessing journal fit and the overall quality of a paper, including the experimental design, the soundness of the study's conclusions, potential impact and innovation. Automated screening tools cannot replace peer review, but may aid authors, reviewers, and editors in improving scientific papers. Strategies for responsible use of automated tools in peer review may include setting performance criteria for tools, transparently reporting tool performance and use, and training users to interpret reports.
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| 26. |
- Scott, Kirk, et al.
(författare)
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Demographic Developments and Economic Challenges in an Aging Europe
- 2017
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Ingår i: Elder Law : Evolving European Perspectives - Evolving European Perspectives. - : Edward Elgar Publishing. - 9781785369087 - 9781785369094 ; , s. 33-52
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Bokkapitel (refereegranskat)abstract
- The world’s population is ageing at a rapid and increasing rate. This chapter discusses the challenges that developing countries face as a consequence of growing shares of the population above retirement age. The chapter discusses reasons why commonly advanced solutions to the ageing challenge are not likely to help. Increasing migration is discussed as a non-solution, as is fertility increase and raising taxes. The most likely solution will be found in a combination of increasing the statutory retirement age and encouraging increased labour force participation among those in working ages.
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| 27. |
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| 28. |
- Sousa-Ribeiro, Marta, et al.
(författare)
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Experiences of Working after Retirement : A Qualitative Study in the Swedish Health Care Sector
- 2018
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Ingår i: Book of Proceedings 13the Conference of the European Academy of Occupational Health Psychology. - Nottingham : European Academy of Occupational Health Psychology. - 9780992878641 ; , s. 267-268
-
Konferensbidrag (refereegranskat)abstract
- Older people represent an increasing share of the population in many countries. While higher life expectancy is a remarkable social achievement, accelerated demographic ageing poses several challenges, particularly to health care, labour market and pensions systems. A greater awareness of the importance to increase the participation of older workers in the labour market and to delay the transition to full retirement has turned retirement into an issue of global significance and an important research topic.Notwithstanding the increasing flexibility and heterogeneity in the exit pathways from employment to retirement, most research have focused on the decision regarding when to retire; while fewer studies have investigated the dynamics of engagement in post-retirement work, or bridge employment. This form of employment is becoming more common in several countries, including Sweden, where between 2010 and 2015, the number of employed people aged 66–74 has increased by 36 percent. Furthermore, qualitative studies, allowing for an in-depth understanding of the complexity of the topic, remain scarce.This study aimed to explore the transition to retirement, the motivation to engage in bridge employment and experiences of working after retirement among assistant nurses. The study used Interpretative Phenomenological Analysis to analyze data from semi-structured interviews with seven retired assistant nurses working at a Swedish hospital. The interviews focused on retirement decision-making, experiences of working after retirement and ageing issues. The following super-ordinate themes were identified: the retirement process, meaning of retirement, functions and meaning of work, drivers to continue working after retirement, working as an assistant nurse after retirement and the experience of ageing. In this group of assistant nurses, bridge employment seemed to allow for a gradual adjustment to retirement, which in turn contributed to their well-being. Interviewees did not plan for their retirement while some would have preferred to do so. Full-retirement was regarded as stagnation and “the end of the road”, while work was valued positively. Work defined one’s existence and identity, provided a sense of purpose and belonging to the society, was a source of social contact and nurturing, a physical and mental health booster and postponed ageing. Interviewees reflected much on their reasons to continue working: Feeling able to work and the absence of major health problems was, not surprisingly, a major driver, but other factors were of equal importance, such as being intrinsically motivated to work and feeling appreciated and needed at work. Interviewees regarded their job as challenging, varied and not particularly demanding. Their contacts with the patients and being able to help others was perceived as highly rewarding and a prominent reason for continuing to work. Having control over working time and opportunities for recovery were also much valued. Interviewees reported some improvements that came with ageing, but also felt some limitations, which they tried to compensate for at work. These results may contribute to a further understanding of issues motivating people to continue working as assistant nurses, an occupation that plays an important role within the health care sector.
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| 29. |
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Supporting Self-regulated Learning Through Digital Badges: A Case Study.
- 2014
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Proceedings (redaktörskap) (refereegranskat)abstract
- Self-regulated learning (SRL) takes place when individuals plan, monitor and evaluate their own learning experiences. Learning assessment plays a crucial role in this process because it provides an excellent basis for the above three phases of SRL; however, the identification, design and implementation of meaningful assessment activities is not easy and some technological affordances for an SRL-sensitive assessment design still need to be explored. Although Digital Badges are already considered an instrument that could provide good answers to the complex problem of assessment for learning, their potential for SRL support is rather under-explored. This paper puts forward a proposal on the role that Digital Badges can play in supporting SRL. The proposal consists in a “badge ecosystem”, developed for a course on “Scientific Information for Biomedical Research”, aimed at differentiating among different levels of competence to facilitate learners in making better informed decisions on how to go about in their learning process. The conclusions discuss the expected advantages and shortcomings of the proposed ecosystem.
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| 30. |
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| 31. |
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| 32. |
- Wang, X., et al.
(författare)
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Development of a Double Hemispherical Probe for Improved Space Plasma Measurements
- 2018
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Ingår i: Journal of Geophysical Research - Space Physics. - : AMER GEOPHYSICAL UNION. - 2169-9380 .- 2169-9402. ; 123:4, s. 2916-2925
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Tidskriftsartikel (refereegranskat)abstract
- Langmuir probes have been widely used for space plasma measurements for decades. However, there are still challenges in the interpretation of their measurements. Due to the interaction of the ambient plasma with a spacecraft and an onboard probe itself, the local plasma conditions around the probe could be very different from the true ambient plasma of interest. These local plasma conditions are often anisotropic and/or inhomogeneous. Most of the Langmuir probes that are made of a single electrode have difficulties to remove these local plasma effects, introducing errors in the derived plasma characteristics. Directional probes are able to characterize anisotropic and inhomogeneous plasmas. The split Langmuir probe and the Segmented Langmuir Probe have been developed to characterize the plasma flow in the Earth's ionosphere. Here we introduce a new type of a directional Langmuir probe, the Double Hemispherical Probe (DHP), to improve the space plasma measurements in a broad range of scenarios: (a) low-density plasmas, (b) high surface-emission (photo and/or secondary electron emission) environments, (c) flowing plasmas, and (d) dust-rich plasma environments. The DHP consists of two identical hemispheres that are electrically insulated and swept with the same voltages simultaneously. The difference currents between the two hemispheres are used to characterize the anisotropic/inhomogeneous plasma conditions created around the probe, which will be then removed or minimized on the interpretation of their current-voltage curves. This paper describes the basic concept and design of the DHP sensor, as well as its initial results tested in the laboratory plasma environments.
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| 33. |
- Zambrano, Jesús, et al.
(författare)
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Microalgae Activated Sludge : Process Modelling and Optimization
- 2017
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Konferensbidrag (refereegranskat)abstract
- This work deals with steady-state optimization of a process formed by an algae-bacteria photo-bioreactor (PBR) in an activated sludge configuration. The optimization is done by considering the total PBR volume as two volumes in series, and aiming for the minimal nitrogen concentration in the effluent, for a given external light and carbon dioxide (CO2) injection. Results suggest that it is possible to obtain an optimum volume distribution that gives a lower effluent substrate concentration compared to a single volume, and this optimum volume depends on the CO2 applied.
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