SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Antó Josep M.) "

Sökning: WFRF:(Antó Josep M.)

  • Resultat 51-53 av 53
  • Föregående 12345[6]
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
51.
  •  
52.
  • Wickman, Magnus, et al. (författare)
  • Detection of IgE Reactivity to a Handful of Allergen Molecules in Early Childhood Predicts Respiratory Allergy in Adolescence
  • 2017
  • Ingår i: EBioMedicine. - : Elsevier BV. - 2352-3964. ; 26, s. 91-99
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Sensitization in early childhood may precede respiratory allergy in adolescence.Methods: IgE reactivity against 132 allergen molecules was evaluated using the MeDALL microarray in sera obtained from a random sample of 786 children at the age of 4, 8 and 16 years in a population based birth cohort (BAMSE). Symptoms were analyzed by questionnaire at ages 4, 8 and 16 years. Clinically and independent relevant allergen molecules accounting for ≥ 90% of IgE reactivities in sensitized individuals and at all time-points were identified as risk molecules and used to predict respiratory allergy. The data was replicated in the Manchester Asthma and Allergy Study (MAAS) birth cohort by studying IgE reactivity with the use of a commercial IgE microarray. Sera were obtained from children at the ages of 3, 5, 8 and 11 years (N = 248) and the outcome was studied at 11 years.Findings: In the BAMSE cohort 4 risk molecules could be identified, i.e.: Ara h 1 (peanut), Bet v 1 (birch), Fel d 1 (cat), Phl p 1 (grass). For MAAS the corresponding number of molecules was 5: Der p 1 (dust mite), Der f 2 (dust mite), Phl p 1 (grass), Phl p 5 (grass), Fel d 1 (cat). In BAMSE, early IgE reactivity to ≥ 3 of 4 allergen molecules at four years predicted incident and persistent asthma and/or rhinitis at 16 years (87% and 95%, respectively). The corresponding proportions in the MAAS cohort at 16 years were 100% and 100%, respectively, for IgE reactivity to ≥ 3 of 5 risk molecules.Interpretations: IgE reactivity to a few allergen molecules early in life identifies children with a high risk of asthma and/or rhinitis at 16 years. These findings will be of importance for developing preventive strategies for asthma and rhinitis in children.
  •  
53.
  • Zock, Jan-Paul, et al. (författare)
  • Domestic use of hypochlorite bleach, atopic sensitization, and respiratory symptoms in adults.
  • 2009
  • Ingår i: The Journal of allergy and clinical immunology. - : Elsevier BV. - 1097-6825 .- 0091-6749. ; 124:4, s. 731-738.e1
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Professional use of hypochlorite (bleach) has been associated with respiratory symptoms. Bleach is capable of inactivating allergens, and there are indications that its domestic use may reduce the risk of allergies in children. OBJECTIVE: To study the associations between household use of bleach and atopic sensitization, allergic diseases, and respiratory health status in adults. METHODS: We identified 3626 participants of the European Community Respiratory Health Survey II in 10 countries who did the cleaning in their homes and for whom data on specific serum IgE to 4 environmental allergens were available. Frequency of bleach use and information on respiratory symptoms were obtained in face-to-face interviews. House dust mite and cat allergens in mattress dust were measured in a subsample. Associations between the frequency of bleach use and health outcomes were evaluated by using multivariable mixed logistic regression analyses. RESULTS: The use of bleach was associated with less atopic sensitization (odds ratio [OR], 0.75; 95% CI, 0.63-0.89). This association was apparent for specific IgE to both indoor (cat) and outdoor (grass) allergens, and was consistent in various subgroups, including those without any history of respiratory problems (OR, 0.85). Dose-response relationships (P < .05) were apparent for the frequency of bleach use and sensitization rates. Lower respiratory tract symptoms, but not allergic symptoms, were more prevalent among those using bleach 4 or more days per week (OR, 1.24-1.49). The use of bleach was not associated with indoor allergen concentrations. CONCLUSION: People who clean their homes with hypochlorite bleach are less likely to be atopic but more likely to have respiratory symptoms.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 51-53 av 53
  • Föregående 12345[6]
Typ av publikation
tidskriftsartikel (49)
forskningsöversikt (4)
Typ av innehåll
refereegranskat (50)
övrigt vetenskapligt (3)
Författare/redaktör
Anto, Josep M. (50)
Heinrich, Joachim (31)
Janson, Christer (26)
Leynaert, Benedicte (22)
Sunyer, Jordi (20)
Jarvis, Deborah (18)
visa fler...
Svanes, Cecilie (17)
Gislason, Thorarinn (16)
Accordini, Simone (14)
Garcia-Aymerich, Jud ... (14)
de Marco, Roberto (12)
Künzli, Nino (12)
Wjst, Matthias (12)
Cerveri, Isa (11)
Pin, Isabelle (11)
Haahtela, Tari (11)
Probst-Hensch, Nicol ... (10)
Carsin, Anne-Elie (10)
Kogevinas, Manolis (10)
Pfaar, Oliver (10)
Klimek, Ludger (10)
Marcon, Alessandro (9)
Melén, Erik (9)
Sheikh, Aziz (9)
Jarvis, Debbie (9)
Kvedariene, Violeta (9)
Devillier, Philippe (9)
Bedbrook, Anna (9)
Czarlewski, Wienczys ... (9)
Morais-Almeida, Mari ... (9)
Cruz, Alvaro A. (9)
Valiulis, Arunas (9)
Kuna, Piotr (9)
Samolinski, Boleslaw (9)
Agache, Ioana (8)
Yorgancioglu, Arzu (8)
Olivieri, Mario (8)
Zock, Jan-Paul (8)
Fokkens, Wytske J. (8)
Zuberbier, Torsten (8)
Ventura, Maria Teres ... (8)
Mullol, Joaquim (8)
Reitsma, Sietze (8)
Weyler, Joost (7)
Norbäck, Dan (7)
Kull, Inger (7)
Wickman, Magnus (7)
Basagana, Xavier (7)
Todo-Bom, Ana (7)
Demoly, Pascal (7)
visa färre...
Lärosäte
Uppsala universitet (39)
Umeå universitet (18)
Karolinska Institutet (10)
Göteborgs universitet (4)
Örebro universitet (2)
Stockholms universitet (1)
visa fler...
Lunds universitet (1)
Chalmers tekniska högskola (1)
visa färre...
Språk
Engelska (53)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (36)
Naturvetenskap (1)
Samhällsvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy