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  • Zhang, Q., et al. (författare)
  • Effect of sintering method on properties of nanosilver paste
  • 2017
  • Ingår i: 2017 IMAPS Nordic Conference on Microelectronics Packaging, NordPac 2017, Goteborg, Sweden, 18-20 June 2017. ; , s. 186-189
  • Konferensbidrag (refereegranskat)abstract
    • Nanoscale silver paste has a good application prospect in heat dissipation of high-power chips due to the characteristics of low temperature sintering and high temperature service. The properties of the nanosilver paste including thermal conductivity, electrical conductivity, and shear strength are affected greatly by the sintering process. The influence of different sintering methods on the performance of the nanosilver paste was studied in this article. The nanosilver paste with 80.5 wt% nano-scale silver particles, 1.5 wt% submicron-scale SiC particles with Ag coating, 0.9 wt% dispersion agent, 10 wt% organic carrier and 7.1 wt% diluting agent was sintered at 260°C for 30 min with three different methods, heating table sintering, heating furnace sintering, and mixed sintering. The samples obtained by mixed sintering process have higher thermal conductivity than the ones obtained by heating furnace sintering method and heating table sintering method. The effect of sintering methods on shear strength of nanosilver paste was also investigated subsequently. Shear testing equipment was used to measure the shear strength of the samples gained by heating table sintering, heating furnace sintering, and air dry oven sintering. The maximum shear strength was obtained for the samples by heating table sintering method. The shear strength of samples by air dry oven sintering method was the minimum one.
  • Zhang, Q., et al. (författare)
  • Mechanical property and reliability of bimodal nano-silver paste with Ag-coated SiC particles
  • 2019
  • Ingår i: Soldering and Surface Mount Technology. - 0954-0911. ; 31:4, s. 193-202
  • Tidskriftsartikel (refereegranskat)abstract
    • © 2019, Emerald Publishing Limited. Purpose: This study aims to develop a bimodal nano-silver paste with improved mechanical property and reliability. Silicon carbide (SiC) particles coated with Ag were introduced in nano-silver paste to improve bonding strength between SiC and Ag particles and enhance high-temperature stability of bimodal nano-silver paste. The effect of sintering parameters such as sintering temperature, sintering time and the proportion of SiC particles on mechanical property and reliability of sintered bimodal nano-silver structure were investigated. Design/methodology/approach: Sandwich structures consist of dummy chips and copper substrates with nickel and silver coating bonded by nano-silver paste were designed for shear testing. Shear strength testing was conducted to study the influence of SiC particles proportions on the mechanical property of sintered nano-silver joints. The reliability of the bimodal nano-silver paste was evaluated experimentally by means of shear test for samples subjected to thermal aging test at 150°C and humidity and temperature testing at 85°C and 85 per cent RH, respectively. Findings: Shear strength was enhanced obviously with the increase of sintering temperature and sintering time. The maximum shear strength was achieved for nano-silver paste sintered at 260°C for 10 min. There was a negative correlation between the proportion of SiC particles and shear strength. After thermal aging testing and humidity and temperature testing for 240 h, the shear strength decreased a little. High-temperature stability and high-hydrothermal stability were improved by the addition of SiC particles. Originality/value: Submicron-scale SiC particles coated with Ag were used as alternative materials to replace part of nano-silver particles to prepare bimodal nano-silver paste due to its high thermal conductivity and excellent mechanical property.
  • Zhang, XY, et al. (författare)
  • Expression pattern of apolipoprotein M during mouse and human embryogenesis
  • 2004
  • Ingår i: Acta Histochemica. - : Elsevier. - 0065-1281. ; 106:2, s. 123-128
  • Tidskriftsartikel (refereegranskat)abstract
    • Apolipoprotein M (apoM) is a recently discovered human apolipoprotein predominantly present in high-density lipoprotein (HDL), and in minor proportions in triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). The gene encoding apoM is present in all mammalian genomes. The identity of the apoM gene of human, rat and mouse is over 80%. However, the (patho)physiological functions of apoM are unknown yet. In the present study, we investigated apoM expression patterns during mouse and human embryogenesis. ApoM transcripts were detectable in mouse embryos from day 7.5 to day 18.5. ApoM was expressed at low levels at day 7.5, its expression increased significantly at day 9.7, decreased at day 10.5, and then increased continually up to day 18.5. ApoM-positive cells appeared mainly in liver of day-12 embryos as detected by in situ hybridization. In day-15 embryos, apoM was expressed in both liver and kidney. During human embryogenesis, apoM was mainly expressed in liver and kidney and little was found in small intestine as determined by mRNA array of human fetal. normal tissues. ApoM was also detected in stomach and skeletal muscle in early stages of embryogenesis (3-5 months). (C) 2004 Elsevier GmbH. All rights reserved.
  • Zhang, XY, et al. (författare)
  • Specific tissue expression and cellular localization of human apolipoprotein M as determined by in situ hybridization
  • 2003
  • Ingår i: Acta Histochemica. - : Elsevier. - 0065-1281. ; 105:1, s. 67-72
  • Tidskriftsartikel (refereegranskat)abstract
    • Apolipoprotein M (apoM) is a recently discovered human apolipoprotein predominantly present in high-density lipoprotein (HDL), and in minor proportion in triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). The gene coding for apoM has been detected in all mammal genomes. The function of apoM is unknown yet. In the present study, we demonstrated that apoM is exclusively expressed in a strong manner in adult liver and kidney, and is expressed weakly in fetal liver and kidney as detected with human multiple tissue expression array. Both immumohistochemical staining and apoM mRNA in situ hybridization demonstrated that apoM was exclusively expressed in hepatocytes in human liver and in tubular epithelial cells in human kidney. The present study helps to elucidate the pathophysiological functions of apoM in vivo.
  • Zhang, Y., et al. (författare)
  • Characterization of nano-enhanced interconnect materials for fine pitch assembly
  • 2014
  • Ingår i: Soldering and Surface Mount Technology. - 0954-0911. ; 26:1, s. 12-17
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose - Multiple fillers are adopted to study the filler influences on electrical and mechanical properties of the conductive adhesives. The performances of the developed nano-enhanced interconnect materials in printing process are also evaluated. The paper aims to discuss these issues. Design/methodology/approach - Micron-sized silver flakes are used as the basic fillers, and submicro- and nano-sized silver spheres and carbon nanotubes (CNTs) are adopted to obtain conductive adhesives with multiple fillers. Differential scanning calorimetry measurement is carried out to characterize the curing behavior of the samples with different fillers, four-probe method is used to obtain the bulk resistivity, shear test is conducted for adhesive strength, and environmental loading test is also involved. Furthermore, printing trials with different patterns have been carried out. Findings -The electrical resistivity of the adhesives with submicro-sized silver spheres does not monotonically change with the increasing sphere proportion, and there exists an optimized value for the ratio of silver flakes to spheres. Samples with relatively small amount of CNT additives show improved electrical properties, while their mechanical strengths tend to decrease. For the printing application, the adhesives with 18.3 volume% filler content behave much better than those with lower filler content of 6 percent. The presence of the nano-particles makes a slight improvement in the printing results. Research limitations/implications - More detailed printing performance and reliability test of the samples need to be carried out in the future. Originality/value - The conductive adhesives as interconnect materials exhibit some improved properties with optimized bimodal or trimodal fillers. The additive of the nano-fillers affects slightly on the printing quality of the bimodal conductive adhesives.
  • Zhang, Y., et al. (författare)
  • Molecular dynamics simulation for the bonding energy of metal-SWNT interface
  • 2011
  • Ingår i: Proceedings - 12th International Conference on Electronic Packaging Technology and High Density Packaging, ICEPT-HDP 2011, Shanghai, 8-11 August 2011. ; , s. 506-509
  • Konferensbidrag (refereegranskat)abstract
    • For this paper, we carried out molecular dynamics simulation to calculate the bonding energy of the metal-SWNT interface. Three kinds of metal, namely iron, nickel and gold, were studied. The results show that the iron-SWNT interface has the strongest bonding energy, and then nickel and gold. To confirm these results, tensile loading tests were also performed to study the breaking force of the metal-SWNT interface. The force needed to debond the metal-SWNT interface is at the order of nano-newton. The more adhesion energy the interface has, the bigger force that must be loaded to break the joint.
  • Zhao, Changhong, 1982, et al. (författare)
  • Synthesis of graphene quantum dots and their applications in drug delivery
  • 2020
  • Ingår i: Journal of Nanobiotechnology. - 1477-3155. ; 18:1
  • Forskningsöversikt (refereegranskat)abstract
    • This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.[Figure not available: see fulltext.]
  • Zhao, M. L., et al. (författare)
  • Modeling of divertor geometry effects in China fusion engineering testing reactor by SOLPS/B2-Eirene
  • 2014
  • Ingår i: Physics of Plasmas. - 1070-664X .- 1089-7674. ; 21:5, s. 052503-
  • Tidskriftsartikel (refereegranskat)abstract
    • The China Fusion Engineering Testing Reactor (CFETR) is currently under design. The SOLPS/B2-Eirene code package is utilized for the design and optimization of the divertor geometry for CFETR. Detailed modeling is carried out for an ITER-like divertor configuration and one with relatively open inner divertor structure, to assess, in particular, peak power loading on the divertor target, which is a key issue for the operation of a next-step fusion machine, such as ITER and CFETR. As expected, the divertor peak heat flux greatly exceeds the maximum steady-state heat load of 10MW/m(2), which is a limit dictated by engineering, for both divertor configurations with a wide range of edge plasma conditions. Ar puffing is effective at reducing divertor peak heat fluxes below 10MW/m(2) even at relatively low densities for both cases, favoring the divertor configuration with more open inner divertor structure.
  • Zheng, Chen, et al. (författare)
  • XOS: An Application-Defined Operating System for Datacenter Computing
  • 2019
  • Ingår i: Proceedings - 2018 IEEE International Conference on Big Data, Big Data 2018. ; , s. 398-407
  • Konferensbidrag (refereegranskat)abstract
    • Rapid growth of datacenter (DC) scale, urgency of cost control, increasing workload diversity, and huge software investment protection place unprecedented demands on the operating system (OS) efficiency, scalability, performance isolation, and backward-compatibility. The traditional OSes are not built to work with deep-hierarchy software stacks, large numbers of cores, tail latency guarantee, and increasingly rich variety of applications seen in modern DCs, and thus they struggle to meet the demands of such workloads.This paper presents XOS, an application-defined OS for modern DC servers. Our design moves resource management out of the OS kernel, supports customizable kernel subsystems in user space, and enables elastic partitioning of hardware resources. Specifically, XOS leverages modern hardware support for virtualization to move resource management functionality out of the conventional kernel and into user space, which lets applications achieve near bare-metal performance. We implement XOS on top of Linux to provide backward compatibility. XOS speeds up a set of DC workloads by up to 1.6× over our baseline Linux on a 24-core server, and outperforms the state-of-the-art Dune by up to 3.3× in terms of virtual memory management. In addition, XOS demonstrates good scalability and strong performance isolation.
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