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Numrering	Referens	Omslagsbild	Hitta
21.	de las Fuentes, L, et al. (författare) Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci 2023 Ingår i: Frontiers in genetics. - : Frontiers Media S.A.. - 1664-8021. ; 14, s. 1235337- Tidskriftsartikel (refereegranskat)
22.	Ingelsson, Erik, 1975-, et al. (författare) Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation 2017 Ingår i: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:6, s. 946- Tidskriftsartikel (refereegranskat)
23.	Kilpelainen, TO, et al. (författare) Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity 2019 Ingår i: Nature communications. - London : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 376- Tidskriftsartikel (refereegranskat)abstract Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we performed genome-wide analyses of circulating HDL cholesterol, LDL cholesterol, and triglyceride levels in up to 120,979 individuals of European, African, Asian, Hispanic, and Brazilian ancestry, with follow-up of suggestive associations in an additional 131,012 individuals. We find four loci, in/near CLASP1, LHX1, SNTA1, and CNTNAP2, that are associated with circulating lipid levels through interaction with physical activity; higher levels of physical activity enhance the HDL cholesterol-increasing effects of the CLASP1, LHX1, and SNTA1 loci and attenuate the LDL cholesterol-increasing effect of the CNTNAP2 locus. The CLASP1, LHX1, and SNTA1 regions harbor genes linked to muscle function and lipid metabolism. Our results elucidate the role of physical activity interactions in the genetic contribution to blood lipid levels.
24.	Luo, Q, et al. (författare) Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence 2023 Ingår i: Cell reports. - : Elsevier BV. - 2211-1247. ; 42:1, s. 112021- Tidskriftsartikel (refereegranskat)
25.	Mao, W, et al. (författare) Bupi Yishen Formula Versus Losartan for Non-Diabetic Stage 4 Chronic Kidney Disease: A Randomized Controlled Trial 2021 Ingår i: Frontiers in pharmacology. - : Frontiers Media SA. - 1663-9812. ; 11, s. 627185- Tidskriftsartikel (refereegranskat)abstract Chinese herbal medicine (CHM) might have benefits in patients with non-diabetic chronic kidney disease (CKD), but there is a lack of high-quality evidence, especially in CKD4. This study aimed to assess the efficacy and safety of Bupi Yishen Formula (BYF) vs. losartan in patients with non-diabetic CKD4. This trial was a multicenter, double-blind, double-dummy, randomized controlled trial that was carried out from 11-08-2011 to 07-20-2015. Patients were assigned (1:1) to receive either BYF or losartan for 48 weeks. The primary outcome was the change in the slope of the estimated glomerular filtration rate (eGFR) over 48 weeks. The secondary outcomes were the composite of end-stage kidney disease, death, doubling of serum creatinine, stroke, and cardiovascular events. A total of 567 patients were randomized to BYF (n = 283) or losartan (n = 284); of these, 549 (97%) patients were included in the final analysis. The BYF group had a slower renal function decline particularly prior to 12 weeks over the 48-week duration (between-group mean difference of eGFR slopes: −2.25 ml/min/1.73 m2/year, 95% confidence interval [CI]: −4.03,−0.47), and a lower risk of composite outcome of death from any cause, doubling of serum creatinine level, end-stage kidney disease (ESKD), stroke, or cardiovascular events (adjusted hazard ratio = 0.61, 95%CI: 0.44,0.85). No significant between-group differences were observed in the incidence of adverse events. We conclude that BYF might have renoprotective effects among non-diabetic patients with CKD4 in the first 12 weeks and over 48 weeks, but longer follow-up is required to evaluate the long-term effects.Clinical Trial Registration:http://www.chictr.org.cn, identifier ChiCTR-TRC-10001518.
26.	Myers, RM, et al. (författare) A user's guide to the encyclopedia of DNA elements (ENCODE) 2011 Ingår i: PLoS biology. - : Public Library of Science (PLoS). - 1545-7885. ; 9:4, s. e1001046- Tidskriftsartikel (refereegranskat)
27.	Pan, YX, et al. (författare) Prognostic Values of Alpha-Fetoprotein and Des-Gamma-Carboxyprothrombin in Hepatocellular Carcinoma in China: An Analysis of 4792 Patients 2021 Ingår i: Journal of hepatocellular carcinoma. - 2253-5969. ; 8, s. 657-670 Tidskriftsartikel (refereegranskat)
28.	Stacey, D, et al. (författare) Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus 2022 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 13:1, s. 1962- Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
29.	Sung, YJ, et al. (författare) A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure 2018 Ingår i: American journal of human genetics. - : Elsevier BV. - 1537-6605 .- 0002-9297. ; 102:3, s. 375-400 Tidskriftsartikel (refereegranskat)
30.	Wang, F, et al. (författare) Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level 2022 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 13:1, s. 6748- Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)

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Resultat 21-30 av 105

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Typ av publikation: tidskriftsartikel (96); konferensbidrag (6); forskningsöversikt (1)

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Författare/redaktör: Chen, XQ (34); Psaty, BM (28); Easton, DF (27); Chenevix-Trench, G (26); Rotter, JI (25); Gudnason, V (24); visa fler...; Couch, FJ (22); Nevanlinna, H (22); Hayward, C. (22); Guo, XQ (22); Ridker, PM (22); Benitez, J. (21); van Duijn, CM (21); Fornage, M (21); Ikram, MA (21); Boerwinkle, E (21); Yao, J (21); Beesley, J (20); Taylor, KD (20); Uitterlinden, AG (19); Chasman, DI (19); Hamann, U (18); Liu, JJ (18); Amin, N (17); Smith, AV (17); Hopper, JL (17); Andrulis, IL (17); Jakubowska, A (17); Schmutzler, RK (17); Morrison, AC (17); Zheng, W. (16); Hall, P (16); Peterlongo, P (16); Anton-Culver, H (16); Milne, RL (16); Launer, LJ (16); Southey, MC (16); Dunning, AM (16); Fasching, PA (16); Beckmann, MW (16); Cox, A (16); Radice, P (16); Nordestgaard, BG (16); Chang-Claude, J (16); Pharoah, PDP (16); Meindl, A (16); Campbell, A (16); Wilson, JF (16); Wareham, NJ (16); Polašek, O. (16); visa färre...

Lärosäte: Karolinska Institutet (103); Lunds universitet (26); Uppsala universitet (22); Göteborgs universitet (9); Umeå universitet (9); Stockholms universitet (4); visa fler...; Linköpings universitet (4); Kungliga Tekniska Högskolan (1); Handelshögskolan i Stockholm (1); Högskolan Dalarna (1); Sveriges Lantbruksuniversitet (1); visa färre...

Språk: Engelska (105)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (38); Naturvetenskap (6)

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