SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Domingo G) ;srt2:(2020-2022);srt2:(2021)"

Sökning: WFRF:(Domingo G) > (2020-2022) > (2021)

  • Resultat 11-16 av 16
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
11.
  • Valiente-Dobón, J.J., et al. (författare)
  • Manifestation of the Berry phase in the atomic nucleus 213Pb
  • 2021
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693. ; 816
  • Tidskriftsartikel (refereegranskat)abstract
    • The neutron-rich 213Pb isotope was produced in the fragmentation of a primary 1 GeV A 238U beam, separated in FRS in mass and atomic number, and then implanted for isomer decay γ-ray spectroscopy with the RISING setup at GSI. A newly observed isomer and its measured decay properties indicate that states in 213Pb are characterized by the seniority quantum number that counts the nucleons not in pairs coupled to angular momentum J=0. The conservation of seniority is a consequence of a geometric phase associated with particle-hole conjugation, which becomes observable in semi-magic nuclei where nucleons half-fill the valence shell. The γ-ray spectroscopic observables in 213Pb are thus found to be driven by two mechanisms, particle-hole conjugation and seniority conservation, which are intertwined through a Berry phase.
  •  
12.
  • Yates, James A. Fellows, et al. (författare)
  • The evolution and changing ecology of the African hominid oral microbiome
  • 2021
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences (PNAS). - 0027-8424 .- 1091-6490. ; 118:20
  • Tidskriftsartikel (refereegranskat)abstract
    • The oral microbiome plays key roles in human biology, health, and disease, but little is known about the global diversity, variation, or evolution of this microbial community. To better understand the evolution and changing ecology of the human oral microbiome, we analyzed 124 dental biofilm metagenomes from humans, including Neanderthals and Late Pleistocene to present-day modern humans, chimpanzees, and gorillas, as well as New World howler monkeys for comparison. We find that a core microbiome of primarily biofilm structural taxa has been maintained throughout African hominid evolution, and these microbial groups are also shared with howler monkeys, suggesting that they have been important oral members since before the catarrhine-platyrrhine split ca. 40 Mya. However, community structure and individual microbial phylogenies do not closely reflect host relationships, and the dental biofilms of Homo and chimpanzees are distinguished by major taxonomic and functional differences. Reconstructing oral metagenomes from up to 100 thousand years ago, we show that the microbial profiles of both Neanderthals and modern humans are highly similar, sharing functional adaptations in nutrient metabolism. These include an apparent Homo-specific acquisition of salivary amylase-binding capability by oral streptococci, suggesting microbial coadaptation with host diet. We additionally find evidence of shared genetic diversity in the oral bacteria of Neanderthal and Upper Paleolithic modern humans that is not observed in later modern human populations. Differences in the oral microbiomes of African hominids provide insights into human evolution, the ancestral state of the human microbiome, and a temporal framework for understanding microbial health and disease.
  •  
13.
  •  
14.
  •  
15.
  • Schlosser, P, et al. (författare)
  • Meta-analyses identify DNA methylation associated with kidney function and damage
  • 2021
  • Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1, s. 7174-
  • Tidskriftsartikel (refereegranskat)abstract
    • Chronic kidney disease is a major public health burden. Elevated urinary albumin-to-creatinine ratio is a measure of kidney damage, and used to diagnose and stage chronic kidney disease. To extend the knowledge on regulatory mechanisms related to kidney function and disease, we conducted a blood-based epigenome-wide association study for estimated glomerular filtration rate (n = 33,605) and urinary albumin-to-creatinine ratio (n = 15,068) and detected 69 and seven CpG sites where DNA methylation was associated with the respective trait. The majority of these findings showed directionally consistent associations with the respective clinical outcomes chronic kidney disease and moderately increased albuminuria. Associations of DNA methylation with kidney function, such as CpGs at JAZF1, PELI1 and CHD2 were validated in kidney tissue. Methylation at PHRF1, LDB2, CSRNP1 and IRF5 indicated causal effects on kidney function. Enrichment analyses revealed pathways related to hemostasis and blood cell migration for estimated glomerular filtration rate, and immune cell activation and response for urinary albumin-to-creatinineratio-associated CpGs.
  •  
16.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 11-16 av 16

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy