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Träfflista för sökning "WFRF:(Hokfelt T) srt2:(2005-2009);srt2:(2007)"

Sökning: WFRF:(Hokfelt T) > (2005-2009) > (2007)

  • Resultat 11-20 av 27
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11.
  • Brumovsky, P, et al. (författare)
  • Neuropeptide tyrosine and pain
  • 2007
  • Ingår i: Trends in pharmacological sciences. - : Elsevier BV. - 0165-6147. ; 28:2, s. 93-102
  • Tidskriftsartikel (refereegranskat)
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15.
  • Fredholm, BB, et al. (författare)
  • G-protein-coupled receptors: an update
  • 2007
  • Ingår i: Acta physiologica (Oxford, England). - 1748-1708. ; 190:1, s. 3-7
  • Tidskriftsartikel (refereegranskat)
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16.
  • Hilke, Susanne, et al. (författare)
  • Cholecystokinin levels in the rat brain during the estrous cycle
  • 2007
  • Ingår i: Brain Research. - : Elsevier BV. - 0006-8993 .- 1872-6240. ; 1144:1, s. 70-73
  • Tidskriftsartikel (refereegranskat)abstract
    • Cholecystokinin (CCK) is widely distributed in the brain, and its expression has been shown to be regulated by estrogen. In the present study we used radioimmunoassay to monitor CCK levels in rat brain during a normal estrous cycle. Compared to di-estrous and estrous, CCK-like immunoreactivity was significantly reduced in cingulate and frontal cortex, hippocampus, striatum and hypothalamus during pro-estrous, that is the phase with the highest plasma estradiol levels. These results provide further evidence that circulating steroid hormones in the female rat can influence expression of a brain peptide, in this case CCK, and primarily in the limbic system, which is interesting in the context that CCK has been associated with anxiety and depression in both animals and humans. © 2007 Elsevier B.V. All rights reserved.
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17.
  • Hokfelt, T, et al. (författare)
  • The central galanin system - an overview
  • 2007
  • Ingår i: EUROPEAN NEUROPSYCHOPHARMACOLOGY. - 0924-977X. ; 17, s. S206-S206
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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19.
  • Huang, HP, et al. (författare)
  • Long latency of evoked quantal transmitter release from somata of locus coeruleus neurons in rat pontine slices
  • 2007
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424. ; 104:4, s. 1401-1406
  • Tidskriftsartikel (refereegranskat)abstract
    • The locus coeruleus (LC) harbors a compact group of noradrenergic cell bodies projecting to virtually all parts of the central nervous system. By using combined measurements of amperometry and patch-clamp, quantal vesicle release of noradrenaline (NA) was detected as amperometric spikes, after depolarization of the LC neurons. After a pulse depolarization, the average latency of amperometric spikes was 1,870 ms, whereas the latency of glutamate-mediated excitatory postsynaptic currents was 1.6 ms. A substantial fraction of the depolarization-induced amperometric spikes originated from the somata. In contrast to glutamate-mediated excitatory postsynaptic currents, NA secretion was strongly modulated by the action potential frequency (0.5–50 Hz). Somatodendritic NA release from LC upon enhanced cell activity produced autoinhibition of firing and of NA release. We conclude that, in contrast to classic synaptic transmission, quantal NA release from LC somata is characterized by a number of distinct properties, including long latency and high sensitivity to action potential frequency.
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  • Resultat 11-20 av 27

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