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Numrering	Referens	Omslagsbild	Hitta
251.	Birnie, K, et al. (författare) Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis 2011 Ingår i: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 6:1, s. e15564- Tidskriftsartikel (refereegranskat)
252.	Ewart, L, et al. (författare) Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery 2018 Ingår i: Annual review of pharmacology and toxicology. - : Annual Reviews. - 1545-4304 .- 0362-1642. ; 58, s. 65-82 Tidskriftsartikel (refereegranskat)abstract Enhancing the early detection of new therapies that are likely to carry a safety liability in the context of the intended patient population would provide a major advance in drug discovery. Microphysiological systems (MPS) technology offers an opportunity to support enhanced preclinical to clinical translation through the generation of higher-quality preclinical physiological data. In this review, we highlight this technological opportunity by focusing on key target organs associated with drug safety and metabolism. By focusing on MPS models that have been developed for these organs, alongside other relevant in vitro models, we review the current state of the art and the challenges that still need to be overcome to ensure application of this technology in enhancing drug discovery.
253.	Hjort, T., et al. (författare) High temperature capable SiC Schottky diodes, based on buried grid design 2014 Ingår i: International Conference and Exhibition on High Temperature Electronics. ; , s. 158-160 Konferensbidrag (refereegranskat)abstract Electrical characteristics of 4H-SiC Schottky barrier diodes, based on buried grid design are presented. The diodes, rated to 1200V/10A and assembled into high temperature capable T0254 packages, have been tested and studied up to 250°C. Compared to conventional SiC Schottky diodes, Ascatron’s buried grid SiC Schottky diode demonstrates several orders of magnitude reduced leakage current at high temperature operation.
254.	Hwang, HJ, et al. (författare) Phospholipase C-β1 potentiates glucose-stimulated insulin secretion 2019 Ingår i: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. - 1530-6860. ; 33:10, s. 10668-10679 Tidskriftsartikel (refereegranskat)
255.	Jang, David H., et al. (författare) Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxide poisoning 2021 Ingår i: Clinical Toxicology. - : Informa UK Limited. - 1556-3650 .- 1556-9519. ; 59:9, s. 801-809 Tidskriftsartikel (refereegranskat)abstract Objectives: The purpose of this study is the development of a porcine model of carbon monoxide (CO) poisoning to investigate alterations in brain and heart mitochondrial function. Design: Two group large animal model of CO poisoning. Setting: Laboratory. Subjects: Ten swine were divided into two groups: Control (n = 4) and CO (n = 6). Interventions: Administration of a low dose of CO at 200 ppm to the CO group over 90 min followed by 30 min of re-oxygenation at room air. The Control group received room air for 120 min. Measurements: Non-invasive optical monitoring was used to measure cerebral blood flow and oxygenation. Cerebral microdialysis was performed to obtain semi real time measurements of cerebral metabolic status. At the end of the exposure, both fresh brain (cortical and hippocampal tissue) and heart (apical tissue) were immediately harvested to measure mitochondrial respiration and reactive oxygen species (ROS) generation and blood was collected to assess plasma cytokine concentrations. Main results: Animals in the CO group showed significantly decreased Complex IV-linked mitochondrial respiration in hippocampal and apical heart tissue but not cortical tissue. There also was a significant increase in mitochondrial ROS generation across all measured tissue types. The CO group showed a significantly higher cerebral lactate-to-pyruvate ratio. Both IL-8 and TNFα were significantly increased in the CO group compared with the Control group obtained from plasma. While not significant there was a trend to an increase in optically measured cerebral blood flow and hemoglobin concentration in the CO group. Conclusions: Low-dose CO poisoning is associated with early mitochondrial disruption prior to an observable phenotype highlighting the important role of mitochondrial function in the pathology of CO poisoning. This may represent an important intervenable pathway for therapy and intervention.
256.	Jang, JY, et al. (författare) DEMENTIA AND MORTALITY IN OLDER ADULTS: A TWIN STUDY 2014 Ingår i: GERONTOLOGIST. - 0016-9013. ; 54, s. 42-42 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
257.	Jang, JY, et al. (författare) Dementia and mortality in older adults: A twin study 2024 Ingår i: Alzheimer's & dementia : the journal of the Alzheimer's Association. - 1552-5279. ; 20:3, s. 1682-1692 Tidskriftsartikel (refereegranskat)
258.	Jang, JY, et al. (författare) DEPRESSION AS A RISK FACTOR FOR SURVIVAL AFTER A DEMENTIA DIAGNOSIS 2011 Ingår i: GERONTOLOGIST. - 0016-9013. ; 51, s. 34-34 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
259.	Jang, Y. M., et al. (författare) Message from organizing chair 2017 Konferensbidrag (refereegranskat)
260.	Jang, Y. M., et al. (författare) Message from Organizing Chairs 2016 Ingår i: 8th International Conference on Ubiquitous and Future Networks, ICUFN 2016. - : IEEE Computer Society. - 2165-8528. ; 2016-August Tidskriftsartikel (refereegranskat)

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