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Search: WFRF:(Jernberg T)

  • Result 61-70 of 262
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61.
  • Björklund, Erik, et al. (author)
  • Admission Troponin T and measurement of ST-segment resolution at 60 min improve early risk stratification in ST-elevation myocardial infarction
  • 2004
  • In: Eur Heart J. - : Oxford University Press (OUP). - 0195-668X .- 1522-9645. ; 25:2, s. 113-20
  • Journal article (peer-reviewed)abstract
    • AIMS: The prognostic value of admission troponin T (tnT) levels and the resolution of the ST-segment elevation in ST-elevation myocardial infarction (STEMI) is well established. However, the combination of these two early available markers for predicting risk has not been evaluated. METHODS AND RESULTS: We evaluated 516 patients with fibrinolytic treated STEMI from the ASSENT-2 and ASSENT-PLUS studies, which had both admission tnT and ST-monitoring available. We used a prospectively defined cut-off value of tnT of 0.1microg/l. For ST-segment resolution, a cut-off of 50% measured after 60min was used. Both a tnT >/=0.1microg/l (n=116) and ST-segment resolution <50% (n=301) were related to higher one-year mortality, 13% vs 4% (P<0.001) and 8.4% vs 2.8% (P=0.009), respectively. In a multivariate analysis ST-segment resolution was and tnT showed a strong trend to be independently related to mortality. The combination of both further improved risk stratification. The one-year mortality in the group with elevation of tnT and without ST-segment resolution compared to the group without tnT elevation and with ST-segment resolution was 18.2% vs 2.8% (P<0.001). CONCLUSIONS: Both tnT on admission and ST-segment resolution after 60min are strong predictors of one-year mortality. The combination of both gives additive early information about prognosis and further improves risk stratification.
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62.
  • Boden, Robert, et al. (author)
  • Higher mortality after myocardial infarction in patients with severe mental illness : a nationwide cohort study
  • 2015
  • In: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 277:6, s. 727-736
  • Journal article (peer-reviewed)abstract
    • ObjectivesThe aim of this study was to explore the impact of severe mental illness (SMI) on myocardial infarction survival and determine the influence of risk factor burden, myocardial infarction severity and different treatments. Design, setting and participantsThis population-based cohort study, conducted in Sweden during the period 1997-2010, included all patients with a first diagnosis of myocardial infarction in the Swedish nationwide myocardial infarction register SWEDEHEART (n=209592). Exposure was defined as a diagnosis of SMI (i.e. bipolar disorder or schizophrenia) in the national patient register prior to infarction. Bias-minimized logistic regression models were identified using directed acyclic graphs and included covariates age, gender, smoking, diabetes, previous cardiovascular disease, myocardial infarction characteristics and treatment. Main outcome measuresThe outcomes were 30-day and 1-year mortality, obtained through linkage with national population registers. ResultsPatients with bipolar disorder (n=442) and schizophrenia (n=541) were younger (mean age 68 and 63years, respectively) than those without SMI (n=208609; mean age 71years). The overall 30-day and 1-year mortality rates were 10% and 18%, respectively. Compared with patients without SMI, patients with SMI had higher 30-day [odds ratio (OR) 1.99, 95% confidence interval (CI) 1.55-2.56] and 1-year mortality (OR 2.11, 95% CI 1.74-2.56) in the fully adjusted model. The highest mortality was observed amongst patients with schizophrenia (30-day mortality: OR 2.58, 95% CI 1.88-3.54; 1-year mortality: OR 2.55, 95% CI 1.98-3.29). ConclusionSMI is associated with a markedly higher mortality after myocardial infarction, also after accounting for contributing factors. It is imperative to identify the reasons for this higher mortality.
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  • Result 61-70 of 262
Type of publication
journal article (154)
conference paper (106)
research review (1)
review (1)
Type of content
other academic/artistic (144)
peer-reviewed (118)
Author/Editor
Jernberg, T (248)
Erlinge, D. (42)
Szummer, K (40)
Lindahl, B (34)
Carrero, JJ (28)
Tornvall, P (22)
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Svensson, P (20)
Wallentin, L (19)
James, S. (18)
Evans, M. (18)
Hambraeus, K. (18)
Lindahl, Bertil (16)
Hofman-Bang, C (15)
Lindahl, Bertil, 195 ... (15)
Alfredsson, J (15)
Lundman, P (14)
Agewall, S (13)
Omerovic, E. (13)
Baron, Tomasz (13)
Frick, M (12)
Ueda, P (12)
Hofmann, R. (11)
Persson, J. (10)
Persson, H (10)
Hemingway, H (10)
Fröbert, Ole, 1964- (9)
Gabrielsen, A (8)
Lund, LH (8)
Sundstrom, J (8)
Soderberg, S (7)
Erlinge, David (7)
Gale, CP (7)
Hall, M. (7)
Sundström, Johan (7)
Hagstrom, E (7)
Faxen, J (7)
Askling, J (7)
Jacobson, SH (6)
Hjemdahl, P (6)
Blomberg, A (6)
Koul, S (6)
Henareh, L (6)
Giannitsis, E (6)
James, Stefan, 1964- (6)
Andell, P. (6)
Lagerqvist, B. (6)
Angeras, O. (6)
Yndigegn, T (6)
Petursson, P. (6)
Kellerth, T (6)
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University
Karolinska Institutet (229)
Uppsala University (59)
University of Gothenburg (25)
Lund University (18)
Örebro University (15)
Umeå University (11)
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Linköping University (11)
University of Borås (4)
Royal Institute of Technology (2)
Stockholm University (1)
Mid Sweden University (1)
Linnaeus University (1)
RISE (1)
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Language
English (262)
Research subject (UKÄ/SCB)
Medical and Health Sciences (67)
Natural sciences (2)
Engineering and Technology (1)
Social Sciences (1)

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