| 21. |
|
|
| 22. |
|
|
| 23. |
- Al-Mamoori, Sohaib Kareem, et al.
(författare)
-
Horizontal and Vertical Geotechnical Variations of Soils According to USCS Classification for the City of An-Najaf, Iraq Using GIS
- 2020
-
Ingår i: Geotechnical and Geological Engineering. - Switzerland : Springer. - 0960-3182 .- 1573-1529. ; 38:2, s. 1919-1938
-
Tidskriftsartikel (refereegranskat)abstract
- The unified soil classification system (USCS) first proposed by Casagrande and subsequently developed by the Army Corps of Engineers. It widely used in many building codes and books. An-Najaf city is the most important city in Iraq due to its religious and spiritual value in the Muslim world, so it is fast expanding and continuous developing city in Iraq. The data from 464 boreholes in the study area for depths of 0–26 m have been used. 13 Soil samples were collected from each borehole with 13 depths level (0–26) m with 2 m intervals. The USCS was applied to the soil samples from 13 depth levels borehole. This research aims to create a geodatabase for soil properties for An-Najaf. The ArcGIS 10.5 software was used to interpolate the spatial data to produce 33 geotechnical maps for fine soil, coarse soil and USCS for 13 depth levels. For numerical soil data, Ordinary Kriging has been used for interpolation mapping of Fine and Coarse percentage data for each depth. For non-numerical (nominal) soil data (USCS class), the Indicator Kriging method is used. The results show that the coarse soil occupied 85–95% for depth 0–16 m and consist of (SP, SP-SM, SM) while fine soil occupied 5–15% consisting of (OL, CH, ML) subsequently, this soil when compacted has a permeability of pervious to semi impervious, good shearing strength, low to very low compressibility and acceptable workability as a construction material. The results also show that after 16 m depths until 26 m, the fine soil percentage increased to 40% with a coarse soil percentage of 60%, indicating changes in soil characteristics as the permeability became semi-pervious to impervious, fair shearing strength, medium compressibility and fair workability as a construction material. The study results will provide help and saving time, efforts and money in preliminary engineering designs.
|
|
| 24. |
- Alawi, Omer A., et al.
(författare)
-
Heat transfer and hydrodynamic properties using different metal-oxide nanostructures in horizontal concentric annular tube : An optimization study
- 2021
-
Ingår i: Nanomaterials. - : MDPI AG. - 2079-4991. ; 11:8
-
Tidskriftsartikel (refereegranskat)abstract
- Numerical studies were performed to estimate the heat transfer and hydrodynamic properties of a forced convection turbulent flow using three-dimensional horizontal concentric annuli. This paper applied the standard k–ε turbulence model for the flow range 1 × 104 ≤ Re ≥ 24 × 103. A wide range of parameters like different nanomaterials (Al2O3, CuO, SiO2 and ZnO), different particle nanoshapes (spherical, cylindrical, blades, platelets and bricks), different heat flux ratio (HFR) (0, 0.5, 1 and 2) and different aspect ratios (AR) (1.5, 2, 2.5 and 3) were examined. Also, the effect of inner cylinder rotation was discussed. An experiment was conducted out using a field-emission scanning electron microscope (FE-SEM) to characterize metallic oxides in spherical morphologies. Nano-platelet particles showed the best enhancements in heat transfer properties, followed by nano-cylinders, nano-bricks, nano-blades, and nano-spheres. The maximum heat transfer enhancement was found in SiO2, followed by ZnO, CuO, and Al2O3, in that order. Meanwhile, the effect of the HFR parameter was insignificant. At Re = 24,000, the inner wall rotation enhanced the heat transfer about 47.94%, 43.03%, 42.06% and 39.79% for SiO2, ZnO, CuO and Al2O3, respectively. Moreover, the AR of 2.5 presented the higher heat transfer improvement followed by 3, 2, and 1.5.
|
|
| 25. |
- Audouze, Karine, et al.
(författare)
-
Evidenced-Based Approaches to Support the Development of Endocrine-Mediated Adverse Outcome Pathways : Challenges and Opportunities
- 2021
-
Ingår i: Frontiers in Toxicology. - : Frontiers Media S.A.. - 2673-3080. ; 3
-
Tidskriftsartikel (refereegranskat)abstract
- A transformation of regulatory toxicology is underway to meet the demands of testing increasing numbers of chemicals whilst reducing reliance on in vivo models. This transformation requires a shift from chemical safety assessment largely based on direct empirical observation of apical toxicity outcomes in whole organisms to predictive approaches in which outcomes and risks are inferred from accumulated mechanistic understanding.
|
|
| 26. |
- Bassyouni, Fatma A., et al.
(författare)
-
Synthesis of new transition metal complexes of 1H-perimidine derivatives having antimicrobial and anti-inflammatory activities
- 2012
-
Ingår i: Research on chemical intermediates (Print). - : Springer Science and Business Media LLC. - 0922-6168 .- 1568-5675. ; 38:7, s. 1527-1550
-
Forskningsöversikt (refereegranskat)abstract
- New series of 1H-perimidine-2-thiol derivatives and (2-substituted-1H-perimidin-1-yl)ethane-1,2-dione derivatives and their ligands (C24H14N4S2O2) H2L1 and (C26H18N4S2O2) H2L2 have been synthesized with transition metal ions, e.g., Copper (II), Silver (I), Cobalt (II) and Ruthenium (III) were prepared and evaluated for their antimicrobial, analgesic and anti-inflammatory activities. The synthesized compounds and their complexes were characterized by elemental analysis, H-1 NMR, IR, MS, molar conductance, thermal gravimetric analysis and electronic spectra. All results revealed that compounds 3 and 13 exhibited high inhibitory effects against some bacterial strains by the disc diffusion method. On the other hand, compounds 2, 3, 7 and 12 displayed potent anti-inflammatory activity.
|
|
| 27. |
- Belal, Amany, et al.
(författare)
-
A Novel Hydroxyapatite/Vitamin B-12 Nanoformula for Treatment of Bone Damage: Preparation, Characterization, and Anti-Arthritic, Anti-Inflammatory, and Antioxidant Activities in Chemically Induced Arthritic Rats
- 2023
-
Ingår i: Pharmaceuticals. - : MDPI. - 1424-8247. ; 16:4
-
Tidskriftsartikel (refereegranskat)abstract
- The usage of nanomaterials for rheumatoid arthritis (RA) treatment can improve bioavailability and enable selective targeting. The current study prepares and evaluates the in vivo biological effects of a novel hydroxyapatite/vitamin B-12 nanoformula in Complete Freunds adjuvant-induced arthritis in rats. The synthesized nanoformula was characterized using XRD, FTIR, BET analysis, HERTEM, SEM, particle size, and zeta potential. We synthesized pure HAP NPs with 71.01% loading weight percentages of Vit B12 and 49 mg/g loading capacity. Loading of vitamin B-12 on hydroxyapatite was modeled by Monte Carlo simulation. Anti-arthritic, anti-inflammatory, and antioxidant effects of the prepared nanoformula were assessed. Treated arthritic rats showed lower levels of RF and CRP, IL-1 beta, TNF-alpha, IL-17, and ADAMTS-5, but higher IL-4 and TIMP-3 levels. In addition, the prepared nanoformula increased GSH content and GST antioxidant activity while decreasing LPO levels. Furthermore, it reduced the expression of TGF-beta mRNA. Histopathological examinations revealed an improvement in joint injuries through the reduction of inflammatory cell infiltration, cartilage deterioration, and bone damage caused by Complete Freunds adjuvant. These findings indicate that the anti-arthritic, antioxidant, and anti-inflammatory properties of the prepared nanoformula could be useful for the development of new anti-arthritic treatments.
|
|
| 28. |
- Christopoulos, Arthur, et al.
(författare)
-
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.
- 2021
-
Ingår i: British journal of pharmacology. - : Wiley. - 1476-5381 .- 0007-1188. ; 178 Suppl 1, s. S27-S156
-
Forskningsöversikt (refereegranskat)abstract
- The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
|
|
| 29. |
|
|
| 30. |
|
|
