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Träfflista för sökning "WFRF:(Li BB) "

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Resultat 81-90 av 90

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Numrering	Referens	Omslagsbild	Hitta
81.	Lu, WS, et al. (författare) PDGFD switches on stem cell endothelial commitment 2022 Ingår i: Angiogenesis. - : Springer Science and Business Media LLC. - 1573-7209 .- 0969-6970. ; 25:4, s. 517-533 Tidskriftsartikel (refereegranskat)abstract The critical factors regulating stem cell endothelial commitment and renewal remain not well understood. Here, using loss- and gain-of-function assays together with bioinformatic analysis and multiple model systems, we show that PDGFD is an essential factor that switches on endothelial commitment of embryonic stem cells (ESCs). PDGFD genetic deletion or knockdown inhibits ESC differentiation into EC lineage and increases ESC self-renewal, and PDGFD overexpression activates ESC differentiation towards ECs. RNA sequencing reveals a critical requirement of PDGFD for the expression of vascular-differentiation related genes in ESCs. Importantly, PDGFD genetic deletion or knockdown increases ESC self-renewal and decreases blood vessel densities in both embryonic and neonatal mice and in teratomas. Mechanistically, we reveal that PDGFD fulfills this function via the MAPK/ERK pathway. Our findings provide new insight of PDGFD as a novel regulator of ESC fate determination, and suggest therapeutic implications of modulating PDGFD activity in stem cell therapy.
82.	Masino, SA, et al. (författare) A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors 2011 Ingår i: The Journal of clinical investigation. - 1558-8238. ; 121:7, s. 2679-2683 Tidskriftsartikel (refereegranskat)
83.	McGrath, LM, et al. (författare) Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study 2014 Ingår i: Journal of the American Academy of Child and Adolescent Psychiatry. - : Elsevier BV. - 1527-5418 .- 0890-8567. ; 53:8, s. 910-919 Tidskriftsartikel (refereegranskat)
84.	Murray, CJL, et al. (författare) Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019 2020 Ingår i: Lancet (London, England). - : Elsevier BV. - 1474-547X .- 0140-6736. ; 396:10258, s. 1223-1249 Tidskriftsartikel (refereegranskat)
85.	NAROD, SA, et al. (författare) An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families. Breast Cancer Linkage Consortium 1995 Ingår i: American journal of human genetics. - 0002-9297. ; 56:1, s. 254-264 Tidskriftsartikel (refereegranskat)
86.	Peden, AE, et al. (författare) Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019 2022 Ingår i: The Lancet. Public health. - 2468-2667. ; 7:8, s. E657-E669 Tidskriftsartikel (refereegranskat)
87.	Schael, S, et al. (författare) Precision electroweak measurements on the Z resonance 2006 Ingår i: Physics Reports. - : Elsevier BV. - 0370-1573 .- 1873-6270. ; 427:5-6, s. 257-454 Forskningsöversikt (refereegranskat)abstract We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLID experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, m(Z) and Gamma(Z), and its couplings to fermions, for example the p parameter and the effective electroweak mixing angle for leptons, are precisely measured: m(Z) = 91.1875 +/- 0.0021 GeV, Gamma(Z) = 2.4952 +/- 0.0023 GeV, rho(l) = 1.0050 +/- 0.0010, sin(2)theta(eff)(lept) = 0.23153 +/- 0.00016. The number of light neutrino species is determined to be 2.9840 +/- 0.0082, in agreement with the three observed generations of fundamental fermions. The results are compared to the predictions of the Standard Model (SM). At the Z-pole, electroweak radiative corrections beyond the running of the QED and QCD coupling constants are observed with a significance of five standard deviations, and in agreement with the Standard Model. Of the many Z-pole measurements, the forward-backward asymmetry in b-quark production shows the largest difference with respect to its SM expectation, at the level of 2.8 standard deviations. Through radiative corrections evaluated in the framework of the Standard Model, the Z-pole data are also used to predict the mass of the top quark, m(t) = 173(+10)(+13) GeV, and the mass of the W boson, m(W) = 80.363 +/- 0.032 GeV. These indirect constraints are compared to the direct measurements, providing a stringent test of the SM. Using in addition the direct measurements of m(t) and m(W), the mass of the as yet unobserved SM Higgs boson is predicted with a relative uncertainty of about 50% and found to be less than 285 GeV at 95% confidence level. (c) 2006 Elsevier B.V. All rights reserved.
88.	Su, XJ, et al. (författare) Prenatal maternal bereavement and risk of eating disorders in infants and toddlers: a population-based cohort study 2015 Ingår i: BMC psychiatry. - : Springer Science and Business Media LLC. - 1471-244X. ; 15, s. 229- Tidskriftsartikel (refereegranskat)
89.	Wu, D, et al. (författare) Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019 2023 Ingår i: EClinicalMedicine. - 2589-5370. ; 64, s. 102193- Tidskriftsartikel (refereegranskat)
90.	Zeng, L, et al. (författare) Cis-epistasis at the LPA locus and risk of cardiovascular diseases 2022 Ingår i: Cardiovascular research. - 1755-3245. ; 118:4, s. 1088-1102 Tidskriftsartikel (refereegranskat)

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Resultat 81-90 av 90

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Typ av publikation: tidskriftsartikel (82); konferensbidrag (1); forskningsöversikt (1)

Typ av innehåll: refereegranskat (81); övrigt vetenskapligt/konstnärligt (3)

Författare/redaktör: Mokdad, AH (37); Fischer, F (35); Jonas, JB (35); Monasta, L (35); Nangia, V (34); Negoi, I (33); visa fler...; Shaikh, MA (33); Hay, SI (32); Mohammed, S (32); Singh, JA (32); Majeed, A (30); Mendoza, W (30); Miller, TR (30); Mirrakhimov, EM (30); Ronfani, L (30); Khader, YS (29); Olagunju, AT (29); Rawaf, S (29); Samy, AM (29); Schwebel, DC (29); Shiri, R (29); Gupta, R. (28); Fereshtehnejad, SM (28); Kisa, A (28); Radfar, A (28); Sepanlou, SG (28); Shigematsu, M (28); Andrei, CL (27); Bensenor, IM (27); Butt, ZA (27); Castaneda-Orjuela, C ... (27); Dandona, R (27); Hamadeh, RR (27); Islam, SMS (27); Defo, BK (27); Malta, DC (27); Mansournia, MA (27); Meretoja, TJ (27); Oh, IH (27); Aljunid, SM (26); Arabloo, J (26); Cardenas, R (26); Dandona, L (26); Hosseinzadeh, M (26); Jha, RP (26); Khan, EA (26); Krishan, K (26); Morrison, SD (26); Roever, L (26); Sathian, B (26); visa färre...

Lärosäte: Karolinska Institutet (85); Uppsala universitet (21); Högskolan Dalarna (18); Lunds universitet (17); Göteborgs universitet (10); Chalmers tekniska högskola (6); visa fler...; Umeå universitet (5); Kungliga Tekniska Högskolan (3); Stockholms universitet (3); Linköpings universitet (2); Jönköping University (2); Mittuniversitetet (1); Södertörns högskola (1); Sveriges Lantbruksuniversitet (1); visa färre...

Språk: Engelska (90)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (41); Naturvetenskap (5); Samhällsvetenskap (2)

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