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Numrering	Referens	Omslagsbild	Hitta
61.	Pham, T, et al. (författare) Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study 2019 Ingår i: Anesthesiology. - : Lippincott Williams and Wilkins. - 1528-1175 .- 0003-3022. ; 130:2, s. 263-283 Tidskriftsartikel (refereegranskat)
62.	Franceschini, N., et al. (författare) GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes 2018 Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 9:1 Tidskriftsartikel (refereegranskat)abstract Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses of genome-wide association studies (GWAS) in 71,128 individuals for cIMT, and 48,434 individuals for carotid plaque traits. We identify eight novel susceptibility loci for cIMT, one independent association at the previously-identified PINX1 locus, and one novel locus for carotid plaque. Colocalization analysis with nearby vascular expression quantitative loci (cis-eQTLs) derived from arterial wall and metabolic tissues obtained from patients with CHD identifies candidate genes at two potentially additional loci, ADAMTS9 and LOXL4. LD score regression reveals significant genetic correlations between cIMT and plaque traits, and both cIMT and plaque with CHD, any stroke subtype and ischemic stroke. Our study provides insights into genes and tissue-specific regulatory mechanisms linking atherosclerosis both to its functional genomic origins and its clinical consequences in humans. © 2018, The Author(s).
63.	Pulit, S. L., et al. (författare) Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes 2018 Ingår i: Neurology-Genetics. - : Ovid Technologies (Wolters Kluwer Health). - 2376-7839. ; 4:6 Tidskriftsartikel (refereegranskat)abstract Objective We sought to assess whether genetic risk factors for atrial fibrillation (AF) can explain cardioembolic stroke risk. We evaluated genetic correlations between a previous genetic study of AF and AF in the presence of cardioembolic stroke using genome-wide genotypes from the Stroke Genetics Network (N = 3,190 AF cases, 3,000 cardioembolic stroke cases, and 28,026 referents). We tested whether a previously validated AF polygenic risk score (PRS) associated with cardioembolic and other stroke subtypes after accounting for AF clinical risk factors. We observed a strong correlation between previously reported genetic risk for AF, AF in the presence of stroke, and cardioembolic stroke (Pearson r = 0.77 and 0.76, respectively, across SNPs with p < 4.4 x 10(-4) in the previous AF meta-analysis). An AF PRS, adjusted for clinical AF risk factors, was associated with cardioembolic stroke (odds ratio [OR] per SD = 1.40, p = 1.45 x 10(-48)), explaining similar to 20% of the heritable component of cardioembolic stroke risk. The AF PRS was also associated with stroke of undetermined cause (OR per SD = 1.07,p = 0.004), but no other primary stroke subtypes (all p > 0.1). Genetic risk of AF is associated with cardioembolic stroke, independent of clinical risk factors. Studies are warranted to determine whether AF genetic risk can serve as a biomarker for strokes caused by AF.
64.	Reitsma, MB, et al. (författare) Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019 2021 Ingår i: Lancet (London, England). - : Elsevier. - 1474-547X .- 0140-6736. ; 397:10292, s. 2337-2360 Tidskriftsartikel (refereegranskat)
65.	Abe, K., et al. (författare) J-PARC Neutrino Beamline Upgrade Technical Design Report 2019 Rapport (refereegranskat)abstract In this document, technical details of the upgrade plan of the J-PARC neutrino beamline for the extension of the T2K experiment are described. T2K has proposed to accumulate data corresponding to 2×1022 protons-on-target in the next decade, aiming at an initial observation of CP violation with 3σ or higher significance in the case of maximal CP violation. Methods to increase the neutrino beam intensity, which are necessary to achieve the proposed data increase, are described.
66.	Kendrick, PJ, et al. (författare) Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019 2021 Ingår i: The Lancet. Public health. - : Elsevier. - 2468-2667. ; 6:7, s. E482-E499 Tidskriftsartikel (refereegranskat)
67.	Lind, Lars, et al. (författare) Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes 2018 Ingår i: Neurology. Genetics. - : LIPPINCOTT WILLIAMS & WILKINS. - 2376-7839. ; 4:6, s. e293- Tidskriftsartikel (refereegranskat)
68.	Shah, PS, et al. (författare) The International Network for Evaluating Outcomes (iNeo) of neonates: evolution, progress and opportunities 2019 Ingår i: Translational pediatrics. - : AME Publishing Company. - 2224-4344 .- 2224-4336. ; 8:3, s. 170- Tidskriftsartikel (refereegranskat)
69.	Walker, GJ, et al. (författare) Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease 2019 Ingår i: JAMA. - : American Medical Association (AMA). - 1538-3598 .- 0098-7484. ; 321:8, s. 773-785 Tidskriftsartikel (refereegranskat)
70.	Lui, K, et al. (författare) Trends in Outcomes for Neonates Born Very Preterm and Very Low Birth Weight in 11 High-Income Countries 2019 Ingår i: The Journal of pediatrics. - : Elsevier BV. - 1097-6833 .- 0022-3476. ; 215, s. 32- Tidskriftsartikel (refereegranskat)

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