| 41. |
- Qi, Nan, et al.
(författare)
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A Task-Driven Sequential Overlapping Coalition Formation Game for Resource Allocation in Heterogeneous UAV Networks
- 2023
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Ingår i: IEEE Transactions on Mobile Computing. - : Institute of Electrical and Electronics Engineers (IEEE). - 1536-1233 .- 1558-0660. ; 22:8, s. 4439-4455
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Tidskriftsartikel (refereegranskat)abstract
- A heterogeneous unmanned aerial vehicle (UAV) network where UAVs carrying different resources form coalition and cooperatively carry out tasks is of crucial importance for fulfilling diverse tasks. However, the existing coalition formation (CF) game model only optimizes the composition of UAVs in a single coalition, which results in disjoined coalitions. In order to tackle this issue, a sequential overlapping coalition formation (OCF) game is proposed by considering the overlapping and complementary relations of resource properties and the task execution order. Moreover, different from the Pareto and selfish orders, a bilateral mutual benefit transfer (BMBT) order is proposed to optimize the cooperative task resource allocation through partial cooperation among overlapping coalition members. Furthermore, using the preference relation between UAVs carrying resources and tasks requiring the same type of resource, a preference gravity-guided tabu search (PGG-TS) algorithm is developed to obtain a stable coalition structure. Numerical results verify that the proposed PGG-TS algorithm increases the average utility of tasks by 12.5% and 38.5% compared with the split-merge preferred OCF algorithm and non-overlapping CF algorithm, respectively. The utility of the proposed BMBT order increases by 25.1% and 34.3% compared with selfish and Pareto orders, respectively.
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| 42. |
- Qi, Nan, et al.
(författare)
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Traffic-Aware Two-Stage Queueing Communication Networks : Queue Analysis and Energy Saving
- 2020
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Ingår i: IEEE Transactions on Communications. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 0090-6778 .- 1558-0857. ; 68:8, s. 4919-4932
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Tidskriftsartikel (refereegranskat)abstract
- To boost energy saving for the general delay-tolerant IoT networks, a two-stage, and single-relay queueing communication scheme is investigated. Concretely, a traffic-aware N-threshold and gated-service policy are applied at the relay. As two fundamental and significant performance metrics, the mean waiting time and long-term expected power consumption are explicitly derived and related with the queueing and service parameters, such as packet arrival rate, service threshold and channel statistics. Besides, we take into account the electrical circuit energy consumptions when the relay server and access point (AP) are in different modes and energy costs for mode transitions, whereby the power consumption model is more practical. The expected power minimization problem under the mean waiting time constraint is formulated. Tight closed-form bounds are adopted to obtain tractable analytical formulae with less computational complexity. The optimal energy-saving service threshold that can flexibly adjust to packet arrival rate is determined. In addition, numerical results reveal that: 1) sacrificing the mean waiting time not necessarily facilitates power savings; 2) a higher arrival rate leads to a greater optimal service threshold; and 3) our policy performs better than the current state-of-the-art.
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| 43. |
- Qi, Nan, et al.
(författare)
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Two Birds With One Stone : Simultaneous Jamming and Eavesdropping With the Bayesian-Stackelberg Game
- 2021
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Ingår i: IEEE Transactions on Communications. - : Institute of Electrical and Electronics Engineers (IEEE). - 0090-6778 .- 1558-0857. ; 69:12, s. 8013-8027
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Tidskriftsartikel (refereegranskat)abstract
- In adversarial scenarios, it is crucial to timely monitor what tactical messages that opponent transmitters are sending to intended receiver(s), and disrupt the transmissions immediately if in need. The issue becomes more challenging in face of an intelligent transmitter. To address the above-stated issue, a full-duplex (FD) technique is utilized to enable simultaneous jamming and eavesdropping (SJE) at a friendly jammer node. In particular, the "Two Birds with One Stone" strategy is utilized at the jammer node to realize effective rate degradation and information eavesdropping. A confrontation game between an intelligence-empowered FD jammer and its opponent is investigated. Specifically, to capture their adversarial relationship in an environment with incomplete information, a power-domain Bayesian-Stackelberg game is proposed. The existence of a Stackelberg equilibrium (SE) power solution is proved. The semi-closed-form solutions of SE are derived, which are proved to be asymptotically optimal (have a gap of less than 1% with the exact utility), and improves the jammer node 10% utility compared with the Nash equilibrium. Additionally, the SJE strategy outperforms the half-duplex (HD) and other benchmark schemes.
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| 44. |
- Shi, Ling-Ling, et al.
(författare)
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Variation in forest soil fungal diversity along a latitudinal gradient
- 2014
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Ingår i: Fungal diversity. - : Springer Science and Business Media LLC. - 1560-2745 .- 1878-9129. ; 64:1, s. 305-315
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Tidskriftsartikel (refereegranskat)abstract
- In forest ecosystems, plant communities shape soil fungal communities through the provisioning of carbon. Although the variation in forest composition with latitude is well established, little is known about how soil fungal communities vary with latitude. We collected soil samples from 17 forests, along a latitudinal transect in western China. Forest types covered included boreal, temperate, subtropical and tropical forests. We used 454 pyrosequencing techniques to analyze the soil communities. These data were correlated with abiotic and biotic variables to determine which factors most strongly influenced fungal community composition. Our results indicated that temperature, latitude, and plant diversity most strongly influence soil fungal community composition. Fungal diversity patterns were unimodal, with temperate forests (mid latitude) exhibiting the greatest diversity. Furthermore, these diversity patterns indicate that fungal diversity was highest in the forest systems with the lowest tree diversity (temperate forests). Different forest systems were dominated by different fungal subgroups, ectomycorrhizal fungi dominated in boreal and temperate forests; endomycorrhizal fungi dominated in the tropical rainforests, and non-mycorrhizal fungi were best represented in subtropical forests. Our results suggest that soil fungal communities are strongly dependent on vegetation type, with fungal diversity displaying an inverse relationship to plant diversity.
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| 45. |
- Shi, Wei, et al.
(författare)
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Pause-melting misalignment: a novel model for the birth and motif indel of tandem repeats in the mitochondrial genome.
- 2013
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Ingår i: BMC genomics. - : Springer Science and Business Media LLC. - 1471-2164. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- ABSTRACT: BACKGROUND: Tandem repeats (TRs) in the mitochondrial (mt) genome control region have been documented in a wide variety of vertebrate species. The mechanism by which repeated tracts originate and undergo duplication and deletion, however, remains unclear. RESULTS: We analyzed DNA sequences of mt genome TRs (mtTRs) in the ridged-eye flounder (Pleuronichthys cornutus), and characterized DNA sequences of mtTRs from other vertebrates using the data available in GenBank. Tandem repeats are concentrated in the control regions; however, we found approximately 16.6% of the TRs elsewhere in the mt genome. The flounder mtTRs possess three motif types with hypervariable characteristics at the 3[prime] end of the control region (CR). CONCLUSION: Based on our analysis of this larger dataset of mtTR sequences, we propose a novel model of Pause Melting Misalignment (PMM) to describe the birth and motif indel of tandem repeats. PMM is activated during a pause event in mitochondrial replication in which a dynamic competition between the nascent (N) heavy strand and the displaced (D) heavy strand may lead to the melting of the N-strand from the template (T) light strand. When mispairing occurs during rebinding of the N-strand, one or several motifs can be inserted or deleted in both strands during the next round of mt-replication or repair. This model can explain the characteristics of TRs in available vertebrate mt genomes.
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| 46. |
- Wang, Mei jun, et al.
(författare)
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SIRT1-dependent deacetylation of Txnip H3K9ac is critical for exenatide-improved diabetic kidney disease
- 2023
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Ingår i: Biomedicine and Pharmacotherapy. - 0753-3322. ; 167
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Tidskriftsartikel (refereegranskat)abstract
- Glucagon-like peptide 1 receptor agonist exenatide (exendin-4) has potential protective capabilities against diabetic kidney disease (DKD). However, the underlying mechanism has not been fully elucidated. The expression of thioredoxin-interacting protein (Txnip) is upregulated during DKD progression by histone acetylation. Sirtuin 1 (SIRT1) is a deacetylase and is decreased in DKD, which indicates that it may regulate Txnip in this disease. Here, we used whole-body heterozygous Sirt1 knockout (Sirt1+/-) and kidney-specific Sirt1 knockout (KSK) mice to investigate whether SIRT1 regulates Txnip via histone deacetylation in DKD and exenatide-alleviated DKD. Exenatide substantially improved renal pathological damage, decreased the albumin-to-creatinine ratio (ACR), upregulated SIRT1 expression, and downregulated Txnip expression in kidneys of high-fat diet-treated C57BL/6J mice. However, these effects diminished in Sirt1+/- and KSK mice under exenatide treatment. The downregulation of Txnip expression by exendin-4 in high-glucose-treated SV40 MES13 cells was hampered during Sirt1 knockdown. These results demonstrate that kidney SIRT1 is indispensable in exenatide-improved DKD and downregulation of Txnip expression. Exendin-4 mechanistically downregulated Txnip histone 3 lysine 9 acetylation (H3K9ac) in a SIRT1-dependent manner and decreased spliced X-box binding protein 1 (XBP1s) recruitment to the Txnip promoter. These findings provide epigenetic evidence elucidating the specific mechanism for exenatide-mediated DKD alleviation and highlight the importance of Txnip as a promising therapeutic target for DKD.
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| 47. |
- Wang, Zhaoming, et al.
(författare)
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Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
- 2014
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Ingår i: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 23:24, s. 6616-6633
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Tidskriftsartikel (refereegranskat)abstract
- Genome-wide association studies (GWAS) have mapped risk alleles for at least 10 distinct cancers to a small region of 63 000 bp on chromosome 5p15.33. This region harbors the TERT and CLPTM1L genes; the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play a role in apoptosis. To investigate further the genetic architecture of common susceptibility alleles in this region, we conducted an agnostic subset-based meta-analysis (association analysis based on subsets) across six distinct cancers in 34 248 cases and 45 036 controls. Based on sequential conditional analysis, we identified as many as six independent risk loci marked by common single-nucleotide polymorphisms: five in the TERT gene (Region 1: rs7726159, P = 2.10 × 10(-39); Region 3: rs2853677, P = 3.30 × 10(-36) and PConditional = 2.36 × 10(-8); Region 4: rs2736098, P = 3.87 × 10(-12) and PConditional = 5.19 × 10(-6), Region 5: rs13172201, P = 0.041 and PConditional = 2.04 × 10(-6); and Region 6: rs10069690, P = 7.49 × 10(-15) and PConditional = 5.35 × 10(-7)) and one in the neighboring CLPTM1L gene (Region 2: rs451360; P = 1.90 × 10(-18) and PConditional = 7.06 × 10(-16)). Between three and five cancers mapped to each independent locus with both risk-enhancing and protective effects. Allele-specific effects on DNA methylation were seen for a subset of risk loci, indicating that methylation and subsequent effects on gene expression may contribute to the biology of risk variants on 5p15.33. Our results provide strong support for extensive pleiotropy across this region of 5p15.33, to an extent not previously observed in other cancer susceptibility loci.
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| 48. |
- Aad, G., et al.
(författare)
-
- 2014
-
Tidskriftsartikel (refereegranskat)
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| 49. |
- Aad, G., et al.
(författare)
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- 2014
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Ingår i: Physical Review C (Nuclear Physics). - 0556-2813 .- 1089-490X. ; 90:4
-
Tidskriftsartikel (refereegranskat)
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| 50. |
- Aad, G., et al.
(författare)
-
- 2015
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Tidskriftsartikel (refereegranskat)
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