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Sökning: WFRF:(Ullén A)

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Numrering	Referens	Omslagsbild	Hitta
61.	Ullen, A., et al. (författare) Prostate cancer cell lines lack amplification: overexpression of HER2 2005 Ingår i: Acta Oncol. - : Informa UK Limited. - 0284-186X .- 1651-226X. ; 44:5, s. 490-5 Tidskriftsartikel (refereegranskat)abstract The potential overexpression of HER2 in prostate cancer cells has attended significant interest during the past few years, both as potential target for HER2 pathway focused therapy and as a mechanism involved in the progression to androgen independence. Conflicting results have been reported concerning HER2 status on clinical material, differences which generally have been attributed to methodological differences. Nevertheless, HER2 has been utilized for targeted therapy of prostate cancer in a number of preclinical studies and is still regarded as an exciting target molecule. In this study, the HER2 status of three widely used prostate cancer cell lines and corresponding xenografts has been analysed. By use of validated and FDA approved analytical staining techniques none of these cell lines or xenografts were shown to overexpress/amplify HER2, as demonstrated by immunohistochemistry and fluorescence in situ hybridization. These findings are important for the interpretation and understanding of the therapeutic effects when developing drugs targeting HER2 in prostate cancer cell lines and also emphasize the importance of using broad and validated analytical techniques.
62.	Ullen, A, et al. (författare) Secondary antibodies as tools to improve tumor to non tumor ratio at radioimmunolocalisation and radioimmunotherapy 1996 Ingår i: Acta oncologica (Stockholm, Sweden). - 0284-186X .- 1651-226X. ; 35:3, s. 281-285 Tidskriftsartikel (refereegranskat)
63.	Ullén, Petrus (författare) Dissertatio philosophica de idea temporis, cujus partem priorem, ... præside ... Mag. Petro Ullén, ... publice ventilandam sistit stipendiarius regius Petrus A. Liljeberg, Vest-Gothus. In Auditorio Carolino Majori die IX Junii Anno MDCCXLIV. H. A. M. S., p. 1 1744 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)
64.	Ullén, Petrus (författare) Speciminis academici, de studiis philosophicis futuro theologo necessariiis, partem posteriorem ... sub præsidio ... Petri Ullén ... pro gradu, publico bonorum examini submittit Sveno A. Fägersten, West-Gothus, in audit. Gust. maj. ad d. 23 Dec. Anni MDCCXXXVI. h.a.m.s., d. 2 1736 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)
65.	Viktorsson, K, et al. (författare) Melphalan-flufenamide is cytotoxic and potentiates treatment with chemotherapy and the Src inhibitor dasatinib in urothelial carcinoma 2016 Ingår i: Molecular oncology. - : Wiley. - 1878-0261 .- 1574-7891. ; 10:5, s. 719-734 Tidskriftsartikel (refereegranskat)
66.	Bernhardt, J, et al. (författare) How to decrease morbidity and mortality of skin cancer: primary prevention of skin cancer/screening of skin cancer. Report of a workshop held under the auspices of the Society of Dermatological Prevention (ADP e.V.), Commission of Early Detection and Prevention of Skin Cancer. 11 May 1994, Hamburg, Germany 1996 Ingår i: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). - : Ovid Technologies (Wolters Kluwer Health). - 0959-8278. ; 5:4, s. 297-299 Tidskriftsartikel (refereegranskat)
67.	Butkovic, A, et al. (författare) Personality related traits as predictors of music practice: Underlying environmental and genetic influences 2015 Ingår i: PERSONALITY AND INDIVIDUAL DIFFERENCES. - : Elsevier BV. - 0191-8869. ; 74, s. 133-138 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
68.	Butkovic, A, et al. (författare) Twin analysis of the association between flow proneness and work-related depressive symptoms and burnout 2017 Ingår i: BEHAVIOR GENETICS. - 0001-8244. ; 47:6, s. 682-683 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
69.	Daws, MR, et al. (författare) H-2Dd engagement of Ly49A leads directly to Ly49A phosphorylation and recruitment of SHP1 1999 Ingår i: Immunology. - 0019-2805. ; 97:4, s. 656-664 Tidskriftsartikel (refereegranskat)
70.	Ebner, Florian, et al. (författare) The association of partial pressures of oxygen and carbon dioxide with neurological outcome after out-of-hospital cardiac arrest : an explorative International Cardiac Arrest Registry 2.0 study 2020 Ingår i: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. - : Springer Science and Business Media LLC. - 1757-7241. ; 28:1, s. 67-67 Tidskriftsartikel (refereegranskat)abstract BACKGROUND: Exposure to extreme arterial partial pressures of oxygen (PaO2) and carbon dioxide (PaCO2) following the return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest (OHCA) is common and may affect neurological outcome but results of previous studies are conflicting.METHODS: Exploratory study of the International Cardiac Arrest Registry (INTCAR) 2.0 database, including 2162 OHCA patients with ROSC in 22 intensive care units in North America and Europe. We tested the hypothesis that exposure to extreme PaO2 or PaCO2 values within 24 h after OHCA is associated with poor neurological outcome at discharge. Our primary analyses investigated the association between extreme PaO2 and PaCO2 values, defined as hyperoxemia (PaO2 > 40 kPa), hypoxemia (PaO2 < 8.0 kPa), hypercapnemia (PaCO2 > 6.7 kPa) and hypocapnemia (PaCO2 < 4.0 kPa) and neurological outcome. The secondary analyses tested the association between the exposure combinations of PaO2 > 40 kPa with PaCO2 < 4.0 kPa and PaO2 8.0-40 kPa with PaCO2 > 6.7 kPa and neurological outcome. To define a cut point for the onset of poor neurological outcome, we tested a model with increasing and decreasing PaO2 levels and decreasing PaCO2 levels. Cerebral Performance Category (CPC), dichotomized to good (CPC 1-2) and poor (CPC 3-5) was used as outcome measure.RESULTS: Of 2135 patients eligible for analysis, 700 were exposed to hyperoxemia or hypoxemia and 1128 to hypercapnemia or hypocapnemia. Our primary analyses did not reveal significant associations between exposure to extreme PaO2 or PaCO2 values and neurological outcome (P = 0.13-0.49). Our secondary analyses showed no significant associations between combinations of PaO2 and PaCO2 and neurological outcome (P = 0.11-0.86). There was no PaO2 or PaCO2 level significantly associated with poor neurological outcome. All analyses were adjusted for relevant co-variates.CONCLUSIONS: Exposure to extreme PaO2 or PaCO2 values in the first 24 h after OHCA was common, but not independently associated with neurological outcome at discharge.

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Resultat 61-70 av 141

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Typ av publikation: tidskriftsartikel (118); konferensbidrag (19); doktorsavhandling (2); annan publikation (1); bokkapitel (1)

Typ av innehåll: refereegranskat (105); övrigt vetenskapligt/konstnärligt (34); populärvet., debatt m.m. (2)

Författare/redaktör: Ullen, A (104); Stigbrand, T. (28); Nilsson, S. (18); Sandstrom, P. (16); Ullén, Fredrik (15); Stigbrand, Torgny (14); visa fler...; Mosing, Miriam A. (13); Riklund, Katrine (12); Johansson, A (12); Madison, Guy (11); Ströck, Viveka (11); Ullén, Anders (11); Ullen, F (11); Jerlström, Tomas, 19 ... (10); Sundström, Birgitta (10); Sandström, P. (10); Sherif, Amir (9); Liedberg, Fredrik (9); Hosseini, A. (9); Park, SH (9); Loriot, Y (9); Holmsten, K (9); Grivas, P (9); Di Pietro, A (8); Erlandsson, A (8); Powles, T. (8); Pappot, H (8); Gurney, H (8); Sternberg, CN (8); Johansson, H (7); Jahnson, Staffan (7); Gardmark, T. (7); Hietala, Sven-Ola (7); Pedersen, Nancy L (7); Nilsson, B (7); Yachnin, J (7); Huang, B. (7); Söderkvist, Karin (7); Hietala, SO (7); Demey, W (7); Häggström, Christel (6); Malmström, Per-Uno (6); Holmberg, Lars (6); Hagberg, Oskar (6); Harmenberg, U. (6); PanaretakiS, T (6); Brandberg, Y (6); Costa, N (6); Erlandsson, Ann (6); Voog, E (6); visa färre...

Lärosäte: Karolinska Institutet (118); Umeå universitet (39); Göteborgs universitet (16); Uppsala universitet (13); Lunds universitet (13); Örebro universitet (12); visa fler...; Linköpings universitet (9); Karlstads universitet (9); Stockholms universitet (3); Kungliga Tekniska Högskolan (2); Handelshögskolan i Stockholm (2); Linnéuniversitetet (1); RISE (1); Naturhistoriska riksmuseet (1); visa färre...

Språk: Engelska (139); Latin (2)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (40); Samhällsvetenskap (15); Naturvetenskap (3); Humaniora (2)

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