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  • Ma, YF, et al. (author)
  • Endothelial Cells Potentially Participate in the Metastasis of Triple-Negative Breast Cancer
  • 2022
  • In: Journal of immunology research. - : Hindawi Limited. - 2314-7156 .- 2314-8861. ; 2022, s. 5412007-
  • Journal article (peer-reviewed)abstract
    • Inhibition of triple-negative breast cancer metastasis has long been a challenge, mainly due to the difficulty in identifying factors that contribute to this process. In this study, freshly isolated triple-negative breast cancer biopsied cells obtained from consenting patients were subjected to flow cytometry and bioinformatic analysis to identify three endothelial cell subclusters: EC (ATP1B3), EC (HSPA1B), and EC (KRT7) in the tumor microenvironment. These endothelial cell subclusters exhibited distinguishing biological features. Based on differentially expressed genes derived from the subclusters, gene set enrichment analysis showed that EC (ATP1B3) and EC (HSPA1B) contribute to the process of metastasis, for example, in fibrosarcoma and anaplastic carcinoma. In this study, we identified the heterogeneity of endothelial cells in the human breast cancer and have provided insights into its role in metastasis.
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  • Result 61-70 of 156
Type of publication
journal article (141)
conference paper (7)
research review (1)
Type of content
peer-reviewed (134)
other academic/artistic (15)
Author/Editor
Jonas, JB (41)
Gupta, R. (39)
Farzadfar, F (33)
Fischer, F (33)
Shiri, R (33)
Murray, CJL (33)
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Kim, YJ (32)
Mokdad, AH (32)
Singh, JA (31)
Yonemoto, N (31)
Khader, YS (30)
Shaikh, MA (30)
Monasta, L (29)
Naghavi, M (29)
Nangia, V (29)
Sepanlou, SG (29)
Lim, SS (29)
Malekzadeh, R (28)
Miller, TR (28)
Alvis-Guzman, N (27)
Butt, ZA (27)
Dandona, L (27)
Hay, SI (27)
Koyanagi, A (27)
Schwebel, DC (27)
Violante, FS (27)
Vos, T (27)
Banach, M (26)
Bhutta, ZA (26)
Dandona, R (26)
Djalalinia, S (26)
Kabir, Z (26)
Kisa, A (26)
Mohammed, S (26)
Moradi-Lakeh, M (26)
Ronfani, L (26)
Younis, MZ (26)
Basu, S (25)
Fereshtehnejad, SM (25)
Hamidi, S (25)
Jozwiak, JJ (25)
Khan, EA (25)
Majeed, A (25)
Mendoza, W (25)
Radfar, A (25)
Rawaf, S (25)
Samy, AM (25)
Shibuya, K (25)
Silva, DAS (25)
Yu, CH (25)
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University
Karolinska Institutet (149)
Lund University (33)
Uppsala University (32)
University of Gothenburg (26)
Högskolan Dalarna (19)
Umeå University (11)
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Chalmers University of Technology (4)
Stockholm University (3)
Linköping University (3)
University of Skövde (3)
Swedish University of Agricultural Sciences (2)
Royal Institute of Technology (1)
Luleå University of Technology (1)
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Language
English (156)
Research subject (UKÄ/SCB)
Medical and Health Sciences (61)
Natural sciences (8)
Social Sciences (2)

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