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Sökning: WFRF:(Wei Wei)

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31.
  • Song, Xiu-Neng, et al. (författare)
  • Theoretical Identification of Three C-66 Fullerene Isomers and Related Chlorinated Derivatives by X-ray Photoelectron Spectroscopy and Near-edge X-ray Absorption Fine Structure Spectroscopy
  • 2016
  • Ingår i: JOURNAL OF PHYSICAL CHEMISTRY A. - : American Chemical Society (ACS). - 1089-5639 .- 1520-5215. ; 120:50, s. 9932-9940
  • Tidskriftsartikel (refereegranskat)abstract
    • C is X-ray photoelectron spectroscopy (XPS) and near-edge X-ray absorption fine structure (NEXAFS) spectra for three C-66 fullerene isomers and related chlorinated species have been calculated by density functional theory (DFT) method. The XPS spectra show isomer dependence for the three, pristine C-66 isomers but not for the chlorinated species. The NEXAFS spectra exhibit strong dependence on the structures of all the investigated molecules and thus can be well employed to identify the three C-66 fullerene isomers and related chlorinated species. Both XPS and NEXAFS spectra of the chlorinated species present significant variations compared with the pristine fullerenes. The spectral components for carbon atoms of different local environments have been explored as well. The spectra for the carbon atoms connecting to chlorine atoms exhibit a significant blue shift compared to the others.
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32.
  • Takeuchi, Fumihiko, et al. (författare)
  • Interethnic analyses of blood pressure loci in populations of East Asian and European descent
  • 2018
  • Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 9:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Blood pressure (BP) is a major risk factor for cardiovascular disease and more than 200 genetic loci associated with BP are known. Here, we perform a multi-stage genome-wide association study for BP (max N = 289,038) principally in East Asians and meta-analysis in East Asians and Europeans. We report 19 new genetic loci and ancestry-specific BP variants, conforming to a common ancestry-specific variant association model. At 10 unique loci, distinct non-rare ancestry-specific variants colocalize within the same linkage disequilibrium block despite the significantly discordant effects for the proxy shared variants between the ethnic groups. The genome-wide transethnic correlation of causal-variant effect-sizes is 0.898 and 0.851 for systolic and diastolic BP, respectively. Some of the ancestry-specific association signals are also influenced by a selective sweep. Our results provide new evidence for the role of common ancestry-specific variants and natural selection in ethnic differences in complex traits such as BP.
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33.
  • Turcot, Valerie, et al. (författare)
  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
  • 2018
  • Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 50:1, s. 26-41
  • Tidskriftsartikel (refereegranskat)abstract
    • Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal genes remains challenging. Here we combined data from 718,734 individuals to discover rare and low-frequency (minor allele frequency (MAF) < 5%) coding variants associated with BMI. We identified 14 coding variants in 13 genes, of which 8 variants were in genes (ZBTB7B, ACHE, RAPGEF3, RAB21, ZFHX3, ENTPD6, ZFR2 and ZNF169) newly implicated in human obesity, 2 variants were in genes (MC4R and KSR2) previously observed to be mutated in extreme obesity and 2 variants were in GIPR. The effect sizes of rare variants are similar to 10 times larger than those of common variants, with the largest effect observed in carriers of an MC4R mutation introducing a stop codon (p.Tyr35Ter, MAF = 0.01%), who weighed similar to 7 kg more than non-carriers. Pathway analyses based on the variants associated with BMI confirm enrichment of neuronal genes and provide new evidence for adipocyte and energy expenditure biology, widening the potential of genetically supported therapeutic targets in obesity.
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34.
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35.
  • Wang, Guang-Wei, et al. (författare)
  • Theoretical Isomer Identification of Three C-56 Fullerenes and Their Chlorinated Derivatives by XPS and NEXAFS Spectra
  • 2016
  • Ingår i: The Journal of Physical Chemistry C. - : American Chemical Society (ACS). - 1932-7447 .- 1932-7455. ; 120:25, s. 13779-13786
  • Tidskriftsartikel (refereegranskat)abstract
    • The C Is X-ray photoelectron spectroscopy (XPS) and near-edge X-ray absorption fine structure (NEXAFS) spectroscopy for three C-56 fullerene isomers and their chlorinated derivatives have been theoretically simulated by means of density functional theory (DFT). Compared with XPS, the NEXAFS spectra present remarkable dependence on the structures of all the studied molecules and thus can be used to identify the three C-56 isomers and chlorinated species. The spectra of the chlorinated species present significant variations compared with the pristine fullerenes. The spectral components of carbon atoms of different local environment have been investigated as well. The spectra of carbons saturated by chlorine atoms exhibit a shift toward higher energies compared with the others.
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36.
  • Wang, Nana, et al. (författare)
  • Perovskite light-emitting diodes based on solution-processed self-organized multiple quantum wells
  • 2016
  • Ingår i: Nature Photonics. - : NATURE PUBLISHING GROUP. - 1749-4885 .- 1749-4893. ; 10:11, s. 699-
  • Tidskriftsartikel (refereegranskat)abstract
    • Organometal halide perovskites can be processed from solutions at low temperatures to form crystalline direct-bandgap semiconductors with promising optoelectronic properties(1-5). However, the efficiency of their electroluminescence is limited by non-radiative recombination, which is associated with defects and leakage current due to incomplete surface coverage(6-9). Here we demonstrate a solution-processed perovskite light-emitting diode (LED) based on self-organized multiple quantum wells (MQWs) with excellent film morphologies. The MQW-based LED exhibits a very high external quantum efficiency of up to 11.7%, good stability and exceptional highpower performance with an energy conversion efficiency of 5.5% at a current density of 100 mA cm(-2). This outstanding performance arises because the lower bandgap regions that generate electroluminescence are effectively confined by perovskite MQWs with higher energy gaps, resulting in very efficient radiative decay. Surprisingly, there is no evidence that the large interfacial areas between different bandgap regions cause luminescence quenching.
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37.
  • Wei, Ting, et al. (författare)
  • Developed and developing world responsibilities for historical climate change and CO2 mitigation
  • 2012
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 109:32, s. 12911-12915
  • Tidskriftsartikel (refereegranskat)abstract
    • At the United Nations Framework Convention on Climate Change Conference in Cancun, in November 2010, the Heads of State reached an agreement on the aim of limiting the global temperature rise to 2 degrees C relative to preindustrial levels. They recognized that long-term future warming is primarily constrained by cumulative anthropogenic greenhouse gas emissions, that deep cuts in global emissions are required, and that action based on equity must be taken to meet this objective. However, negotiations on emission reduction among countries are increasingly fraught with difficulty, partly because of arguments about the responsibility for the ongoing temperature rise. Simulations with two earth-system models (NCAR/CESM and BNU-ESM) demonstrate that developed countries had contributed about 60-80%, developing countries about 20-40%, to the global temperature rise, upper ocean warming, and sea-ice reduction by 2005. Enacting pledges made at Cancun with continuation to 2100 leads to a reduction in global temperature rise relative to business as usual with a 1/3-2/3 (CESM 33-67%, BNU-ESM 35-65%) contribution from developed and developing countries, respectively. To prevent a temperature rise by 2 degrees C or more in 2100, it is necessary to fill the gap with more ambitious mitigation efforts.
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38.
  • Wei, T., et al. (författare)
  • Quantitative Estimation of the Climatic Effects of Carbon Transferred by International Trade
  • 2016
  • Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 6
  • Tidskriftsartikel (refereegranskat)abstract
    • Carbon transfer via international trade affects the spatial pattern of global carbon emissions by redistributing emissions related to production of goods and services. It has potential impacts on attribution of the responsibility of various countries for climate change and formulation of carbon-reduction policies. However, the effect of carbon transfer on climate change has not been quantified. Here, we present a quantitative estimate of climatic impacts of carbon transfer based on a simple CO2 Impulse Response Function and three Earth System Models. The results suggest that carbon transfer leads to a migration of CO2 by 0.1-3.9 ppm or 3-9% of the rise in the global atmospheric concentrations from developed countries to developing countries during 1990-2005 and potentially reduces the effectiveness of the Kyoto Protocol by up to 5.3%. However, the induced atmospheric CO2 concentration and climate changes (e.g., in temperature, ocean heat content, and sea-ice) are very small and lie within observed interannual variability. Given continuous growth of transferred carbon emissions and their proportion in global total carbon emissions, the climatic effect of traded carbon is likely to become more significant in the future, highlighting the need to consider carbon transfer in future climate negotiations.
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39.
  • Wei, Wei, et al. (författare)
  • Gradient-driven parking navigation using a continuous information potential field based on wireless sensor network
  • 2017
  • Ingår i: Information Sciences. - : Elsevier. - 0020-0255 .- 1872-6291. ; 408, s. 100-114
  • Tidskriftsartikel (refereegranskat)abstract
    • Wireless sensor networks can support building and transportation system automation in numerous ways. An emerging application is to guide drivers to promptly locate vacant parking spaces in large parking structures during peak hours. This paper proposes efficient parking navigation via a continuous information potential field and gradient ascent method. Our theoretical analysis proves the convergence of a proposed algorithm and efficient convergence during the first and second steps of the algorithm to effectively prevent parking navigation from a gridlock situation. The empirical study demonstrates that the proposed algorithm performs more efficiently than existing algorithms.
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40.
  • Wei, Zhu, et al. (författare)
  • Injectable and assembled 3D solid structure for free-to-fixed shape in bone reconstruction
  • 2020
  • Ingår i: Applied Materials Today. - : Elsevier BV. - 2352-9407. ; 21
  • Tidskriftsartikel (refereegranskat)abstract
    • There is a gap between injectable and scaffold-like bioceramics. Injectable bioactive materials, such as bone cement and hydrogel, are good for minimized surgery, but the extremely low porosity and small pore size limited enhanced bone repair and regeneration. Macroporous bioceramic scaffolds are used because of the controlled pore size and porosity, but not injectable. It's a challenge of preparation of an injectable macroporous ceramic scaffold for minimized bone reconstruction. By using the reversible setting reaction of calcium sulfate and combining a dual setting system with magnesium silicate hydrate, the injectable and assembled 3D porous bioceramic scaffold has been successfully developed. The content of amorphous magnesium silicate hydrate in the dual setting system affected the mechanical strength and degradation. The porous structure could be controlled by the size of granules. The granules can also be used for the fabrication of porous materials with varied shapes and customized structures by using a simple injection process. The biological testing showed good biocompatibility and in vitro osteogenesis. By using the femoral lateral condyle defect model, we can see the granules could be injected into the defect and formed a rigid porous structure in situ, and further presented better new bone formation compared with autologous bone chips. Briefly, we demonstrated the first injectable 3D solid porous ceramic structure for minimized bone repair and free-form shaping.
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