| 61. |
- Zhao, Yang, et al.
(författare)
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Provincial heterogeneity in the management of care cascade for hypertension, diabetes, and dyslipidaemia in China: Analysis of nationally representative population-based survey.
- 2022
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Ingår i: Frontiers in cardiovascular medicine. - : Frontiers Media SA. - 2297-055X. ; 9
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Tidskriftsartikel (refereegranskat)abstract
- This study aims to examine (1) province-level variations in the levels of cardiovascular disease (CVD) risk and behavioral risk for CVDs, (2) province-level variations in the management of cascade of care for hypertension, diabetes, and dyslipidaemia, and (3) the association of province-level economic development and individual factors with the quality of care for hypertension, diabetes, and dyslipidaemia.We used nationally representative data from the China Health and Retirement Longitudinal Study in 2015, which included 12,597 participants aged 45 years. Using a care cascade framework, we examined the quality of care provided to patients with three prevalent NCDs: hypertension, diabetes, and dyslipidaemia. The proportion of WHO CVD risk based on the World Health Organization CVD risk prediction charts, Cardiovascular Risk Score (CRS) and Behavior Risk Score (BRS) were calculated. We performed multivariable logistic regression models to determine the individual-level drivers of NCD risk variables and outcomes. To examine socio-demographic relationships with CVD risk, linear regression models were applied.In total, the average CRS was 4.98 (95% CI: 4.92, 5.05), while the average BRS was 3.10 (95% confidence interval: 3.04, 3.15). The weighted mean CRS (BRS) in Fujian province ranged from 4.36 to 5.72 (P < 0.05). Most of the provinces had a greater rate of hypertension than diabetes and dyslipidaemia awareness and treatment. Northern provinces had a higher rate of awareness and treatment of all three diseases. Similar patterns of regional disparity were seen in diabetes and dyslipidaemia care cascades. There was no evidence of a better care cascade for CVDs in patients who reside in more economically advanced provinces.Our research found significant provincial heterogeneity in the CVD risk scores and the management of the cascade of care for hypertension, diabetes, and dyslipidaemia for persons aged 45 years or more. To improve the management of cascade of care and to eliminate regional and disparities in CVD care and risk factors in China, local and population-based focused interventions are necessary.
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| 62. |
- Zhao, Yi, et al.
(författare)
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Redox Dual-Cocatalyst-Modified CdS Double-Heterojunction Photocatalysts for Efficient Hydrogen Production
- 2020
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Ingår i: ACS Applied Materials and Interfaces. - : American Chemical Society (ACS). - 1944-8244 .- 1944-8252. ; 12:41, s. 46073-46083
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Tidskriftsartikel (refereegranskat)abstract
- Cadmium sulfide (CdS) as one of the most common visible-light-responsive photocatalysts has been widely investigated for hydrogen generation. However, its low solar-hydrogen conversion efficiency caused by fast carrier recombination and poor catalytic activity hinders its practical applications. To address this issue, we develop a novel and highly efficient nickel-cobalt phosphide and phosphate cocatalyst-modified CdS (NiCoP/CdS/NiCoPi) photocatalyst for hydrogen evolution. The dual-cocatalysts were simultaneously deposited on CdS during one phosphating step by using sodium hypophosphate as the phosphorus source. After the loading of the dual-cocatalysts, the photocurrent of CdS significantly increased, while its electrical impedance and photoluminescence emission dramatically decreased, which indicates the enhancement of charge carrier separation. It was proposed that the NiCoP cocatalyst accepts electrons and promotes hydrogen evolution, while the NiCoPi cocatalyst donates electrons and accelerates the oxidation of sacrificial agents (e.g., lactic acid). Consequently, the visible-light-driven hydrogen evolution of this composite photocatalyst greatly improved. The dual-cocatalyst-modified CdS with a loading content of 5 mol % showed a high hydrogen evolution rate of 80.8 mmol.g(-1).h(-1), which was 202 times higher than that of bare CdS (0.4 mmol.g(-1).h(-1)). This is the highest enhancement factor for metal phosphide-modified CdS photocatalysts. It also exhibited remarkable stability in a continuous photocatalytic test with a total reaction time of 24 h.
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| 63. |
- Zhao, Yongmei, et al.
(författare)
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Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study
- 2021
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Ingår i: Scientific Data. - : Springer Nature. - 2052-4463. ; 8:1
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Tidskriftsartikel (refereegranskat)abstract
- With the rapid advancement of sequencing technologies, next generation sequencing (NGS) analysis has been widely applied in cancer genomics research. More recently, NGS has been adopted in clinical oncology to advance personalized medicine. Clinical applications of precision oncology require accurate tests that can distinguish tumor-specific mutations from artifacts introduced during NGS processes or data analysis. Therefore, there is an urgent need to develop best practices in cancer mutation detection using NGS and the need for standard reference data sets for systematically measuring accuracy and reproducibility across platforms and methods. Within the SEQC2 consortium context, we established paired tumor-normal reference samples and generated whole-genome (WGS) and whole-exome sequencing (WES) data using sixteen library protocols, seven sequencing platforms at six different centers. We systematically interrogated somatic mutations in the reference samples to identify factors affecting detection reproducibility and accuracy in cancer genomes. These large cross-platform/site WGS and WES datasets using well-characterized reference samples will represent a powerful resource for benchmarking NGS technologies, bioinformatics pipelines, and for the cancer genomics studies.
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| 64. |
- Zhou, F. F., et al.
(författare)
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Teleconnections between large-scale oceanic-atmospheric patterns an interannual surface wind speed variability across China: Regional and seasonal patterns
- 2022
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Ingår i: Science of the Total Environment. - : Elsevier BV. - 0048-9697. ; 838
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Tidskriftsartikel (refereegranskat)abstract
- Great attention has been paid to the long-term decline in terrestrial near-surface wind speed (SWS) in China. However, how the SWS varies with regions and seasons and what modulates these changes remain unclear. Based on quality-controlled and homogenized terrestrial SWS data from 596 stations, the covarying SWS patterns during the Asian Summer Monsoon (ASM) and the Asian Winter Monsoon (AWM) seasons are defined for China using empirical orthogonal function (EOF) analysis for 1961-2016. The dominant SWS features represented by EOF1 patterns in both seasons show a clear decline over most regions of China. The interannual variability of the EOF1 patterns is closely related to the Northeast Asia Low Pressure (NFAIP) and the Arctic Oscillation (AO), respectively. The EOF2 and EOF3 patterns during ASM (AWM) season describe a dipole mode of SWS between Fast Tibetan Plateau and Fast China Plain (between Fast Tibetan Plateau and Northeast China), and between Southeast and Northeast China (between Northeast China and the coastal areas of Southeast China), respectively. These dipole structures of SWS changes arc closely linked with the oceanic-atmospheric oscillations on interannual scale.
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