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  • Boström, Henrik, et al. (författare)
  • On the Definition of Information Fusion as a Field of Research
  • 2007
  • Rapport (övrigt vetenskapligt)abstract
    • A more precise definition of the field of information fusion can be of benefit to researchers within the field, who may use uch a definition when motivating their own work and evaluating the contribution of others. Moreover, it can enable researchers and practitioners outside the field to more easily relate their own work to the field and more easily understand the scope of the techniques and methods developed in the field. Previous definitions of information fusion are reviewed from that perspective, including definitions of data and sensor fusion, and their appropriateness as definitions for the entire research field are discussed. Based on strengths and weaknesses of existing definitions, a novel definition is proposed, which is argued to effectively fulfill the requirements that can be put on a definition of information fusion as a field of research.
  • Dagbro, Ola, et al. (författare)
  • Colour responses from wood, thermally modified in superheated steam and pressurized steam atmospheres
  • 2010
  • Ingår i: Wood Material Science & Engineering. - : Taylor & Francis Group. - 1748-0272 .- 1748-0280. ; 5:3, s. 211-219
  • Tidskriftsartikel (refereegranskat)abstract
    • In this study, two different methods were used to produce thermally modified wood. One was carried out in a typical kiln drying chamber using superheated steam (SS) and the other used pressurized steam in an autoclave cylinder (PS). Overall, both processes followed the same principles and the wood was not treated with any chemicals. Two wood species were studied, Scots pine (Pinus sylvestris) and Norway spruce (Picea abies). Treatments in the autoclave were carried out under pressure using temperatures of 160°C, 170°C and 180°C. Temperatures of 190°C and 212°C were used in treatments in the chamber at normal air pressure. The colour was measured using L*C*H colour space. Results for both species showed that similar L* (lightness) can be reached at lower (20-308C) temperatures using PS compared with SS treatment. The hue angle of PS-treated wood was smaller than that of SS-treated wood. No significant difference in C* (chroma) was detected. The difference in E value between PS- and SS-treated wood was smaller for Norway spruce than for Scots pine. The residual moisture content was about 10% higher in wood treated by the PS process compared with the SS process
  • Elgqvist, Jörgen, 1963, et al. (författare)
  • Therapeutic efficacy and tumor dose estimations in radioimmunotherapy of intraperitoneally growing OVCAR-3 cells in nude mice with (211)At-labeled monoclonal antibody MX35
  • 2005
  • Ingår i: J Nucl Med. - 0161-5505. ; 46:11, s. 1907-15
  • Tidskriftsartikel (refereegranskat)abstract
    • The purpose of this study was to investigate the therapeutic efficacy of-and to estimate the absorbed dose to-tumor cells from radioimmunotherapy (RIT) in an ovarian cancer model using the alpha-particle-emitting nuclide (211)At labeled to monoclonal antibody (mAb) MX35. Previous studies on mAb MOv18 did not allow for dosimetry because of antigen shedding in vitro. METHODS: Five-week-old female nude BALB/c nu/nu mice were inoculated intraperitoneally with 1 x 10(7) cells of the human tumor cell line OVCAR-3. Three weeks later, the animals were given approximately 400, 800, or 1,200 kBq of (211)At-labeled mAb MX35 intraperitoneally. As controls, one group of animals was injected with unlabeled mAb and another group was injected with phosphate-buffered saline (PBS). Another group was given approximately 400 kBq of (211)At labeled to the previously investigated mAb MOv18 for efficacy comparison. Two months after treatment, the animals were sacrificed and the presence of macroscopic and microscopic tumors, as well as ascites, was determined. The absorbed dose to tumor cells on the peritoneal surface was estimated in terms of the sum of a specific and a nonspecific contribution. The specific contribution, arising from mAbs binding to the antigenic sites on the cell membrane, was calculated using a dynamic compartment model developed in-house and Monte Carlo software. The model used as input values the number of mAbs injected into the abdominal cavity, N(mAb), the specific activity, A(sp), the association rate constant, k(on), and the maximal number of mAbs bound per cell, B(max)-all determined by in vitro experiments. This specific component of the absorbed dose was calculated for assumed cell cluster sizes with radii of 25, 50, and 100 microm. The nonspecific contribution to the absorbed dose was derived from unbound mAbs freely circulating in the abdominal cavity, also using the Monte Carlo software. RESULTS: In the control groups given unlabeled MX35 or PBS, all 18 animals had ascites, 6 of 9 animals in each group had macroscopic tumors, and all animals had microscopic growth. In the 3 groups given different amounts of (211)At-MX35, only 3 of 25 animals developed ascites. None of these animals had any sign of macroscopic tumors, but 8 had microscopic growth. In the group given (211)At-MOv18, no animals had ascites or macroscopic tumors, but 3 of 10 animals had microscopic tumors. After injecting 400 kBq of (211)At-MX35, the absorbed dose due to specific binding, for a cell cluster with a radius of 50 microm, ranged from 413 to 223 Gy between 0- and 45-microm distance from the cluster center, assuming a homogeneous distribution of (211)At-MX35 in the cluster. The contribution from unbound (211)At-MX35 and (211)At-MX35 only distributed on the cluster surface, for this cluster size, ranged from 7 to 14 Gy and from 29 to 94 Gy, between 0- and 45-microm distance from the cluster center, respectively. The calculated total absorbed doses are in a clinically relevant range and were effective as verified in the nude mice with subclinical intraperitoneal growth of OVCAR-3 cells. CONCLUSION: (211)At-MX35 injected intraperitoneally exhibits a high efficacy when treating micrometastatic growth of the ovarian cancer cell line OVCAR-3 on the peritoneum of nude mice.
  • Firtin, Cemil Eren, et al. (författare)
  • Calculation, justification, and medical profession: Introduction of performance appraisals and pecuniary incentives within an emergency unit
  • 2019
  • Ingår i: The Centre for Global Human Resource Management, International Interdisciplinary Conference on HRM, 03-05 April 2019, Gothenburg.
  • Konferensbidrag (övrigt vetenskapligt)abstract
    • In this article, we address the issues of calculation and economization within contemporary public organizations. We address issues of how choices of organizing emergency health care have been affected by a production of calculation. More specifically, we pay specific attention to how the use of performance appraisals, in terms of calculations and valuations, has become important components in the construction of pecuniary incentives for individual professionals within healthcare organizations. Drawing on empirical data from 12 in-depth interviews at three different emergency health care sites, the analysis reveals how calculation and accounting as a performative act shapes professional work. This article contributes to the growing literature focusing on accountingization by showing how the calculations enable the meet between accounting and medical profession and demonstrating the performative consequences of accounting on the medical work.
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