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- Haikola, Simon, 1982-, et al.
(författare)
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The making of mining expectations : Mining romanticism and historical memory in a neoliberal political landscape
- 2018
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Ingår i: Social & cultural geography (Print). - : Taylor & Francis. - 1464-9365 .- 1470-1197. ; 19:5, s. 576-605
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Tidskriftsartikel (refereegranskat)abstract
- This paper investigates a greenfield mining project in a peripheral region in northern Sweden through the analysis of how different actor groups formed their own ‘horizons of expectations’ that temporally became fused, only to crumble together with the mining company in a short period of time. By focusing on the co-evolvement of expectations, we show how expectations are differentiated along geographical and temporal scales, reflect upon how these differences relate to interests and historical memory, and finally what these differences mean for the development of large-scale, long-term, raw materials-based projects devoted to industrial production in depopulating areas in an economy otherwise orientated towards neoliberal governance and post-industrial development. By doing so, we make a theoretical contribution to the literature on expectations through the introduction of the concept ‘horizon of expectations’, and a contribution to the literature on neoliberalism and its cultural-geographical implications.
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- Barranco, I., et al.
(författare)
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The activity of paraoxonase type 1 (PON-1) in boar seminal plasma and its relationship with sperm quality, functionality, and in vivo fertility
- 2015
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Ingår i: Andrology. - : American Society of Andrology. - 2047-2919 .- 2047-2927. ; 3:2, s. 315-320
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Tidskriftsartikel (refereegranskat)abstract
- Paraoxonase 1 (PON-1) is a hydrolytic enzyme present in body fluids, capable of protecting cells against oxidative stress. The hypothesis was hereby to test that PON-1, present in seminal plasma (SP), acts protecting boar spermatozoa when showing a reasonable high activity in the ejaculate. SP-PON-1 activity differed (pless than0.001) among boars (from 0.10 to 0.29IU/mL). Intra-boar variability was also observed (pless than0.05), but only in two of the 15 boars. SP-PON-1 activity differed among ejaculate portions, showing the spermatozoa-peak portion of spermatozoa-rich ejaculate fraction the highest levels (0.35 +/- 0.03IU/mL, ranging from 0.12 to 0.69) and the post-sperm ejaculate fraction the lowest levels (0.12 +/- 0.01IU/mL, ranging from 0.03 to 0.21). SP-PON-1 activity was positively correlated with the percentage of spermatozoa with rapid and progressive movement (pless than0.01) and negatively correlated with the generation of intracellular reactive oxygen species (pless than0.01) in semen samples after 72h of liquid storage. SP-PON-1 activity was highest (pless than0.01) in boars with highest farrowing rates. In conclusion, SP-PON-1 activity differed among boars and ejaculate fractions/portions. SP-PON-1 activity was positively correlated with sperm quality and functionality of liquid-stored semen samples and it evidenced a positive association with in vivo fertility.
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- Barranco, Isabel, et al.
(författare)
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The Seminal Plasma of the Boar is Rich in Cytokines, with Significant Individual and Intra-Ejaculate Variation
- 2015
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Ingår i: American Journal of Reproductive Immunology. - : WILEY-BLACKWELL. - 1046-7408 .- 1600-0897. ; 74:6, s. 523-532
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Tidskriftsartikel (refereegranskat)abstract
- Problem The boar, as human, sequentially ejaculates sperm-rich and sperm-poor fractions. Seminal plasma (SP) spermadhesins (PSP-I/PSP-II) induce a primary endometrial inflammatory response in female sows, similar to that elicited by semen deposition in other species, including human. However, the SP is also known to mitigate such response, making it transient to allow for embryo entry to a cleansed endometrium. Although cytokine involvement has been claimed, the exploration of cytokines in different SP fractions is scarce. This study determines Th1, Th2, Th17 and Th3 cytokine profiles in specific ejaculate SP fractions from boars of proven fertility. Methods SP samples from the sperm-rich fraction (SRF) and the sperm-poor post-SRF fraction (post-SRF) of manually collected ejaculates from eight boars (four ejaculates per boar) were analysed by commercial multiplex bead assay kits (Milliplex MAP, Millipore, USA) for interferon-gamma, interferon gamma-induced protein 10, macrophage-derived chemokine, growth-regulated oncogene, granulocyte-macrophage colony-stimulating factor, monocyte chemo-attractant protein-1, interleukins (IL)-6, IL-8, IL-10, IL-15, IL-17 and transforming growth factor (TGF)-beta 1-beta 3. Results Cytokine concentrations differed between the ejaculate fractions among boars, being highest in the post-SRF. Conclusion Boar SP is rich in Th1, Th2, Th17 and Th3 cytokines, with lowest concentrations in the sperm-peak-containing fraction, indicating its main immune influence might reside in the larger, protein-rich sperm-poor post-SRF.
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- Diaz-Morales, Oscar, et al.
(författare)
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Catalytic effects of molybdate and chromate–molybdate films deposited on platinum for efficient hydrogen evolution
- 2023
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Ingår i: Journal of chemical technology and biotechnology (1986). - : Wiley. - 0268-2575 .- 1097-4660. ; 98:5, s. 1269-1278
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Sodium chlorate (NaClO3) is extensively used in the paper industry, but its production uses strictly regulated highly toxic Na2Cr2O7 to reach high hydrogen evolution reaction (HER) Faradaic efficiencies. It is therefore important to find alternatives either to replace Na2Cr2O7 or reduce its concentration.RESULTS: The Na2Cr2O7 concentration can be significantly reduced by using Na2MoO4 as an electrolyte co-additive. Na2MoO4 in the millimolar range shifts the platinum cathode potential to less negative values due to an activating effect of cathodically deposited Mo species. It also acts as a stabilizer of the electrodeposited chromium hydroxide but has a minor effect on the HER Faradaic efficiency. X-ray photoelectron spectroscopy (XPS) results show cathodic deposition of molybdenum of different oxidation states, depending on deposition conditions. Once Na2Cr2O7 was present, molybdenum was not detected by XPS, as it is likely that only trace levels were deposited. Using electrochemical measurements and mass spectrometry we quantitatively monitored H2 and O2 production rates. The results indicate that 3 μmol L−1 Na2Cr2O7 (contrary to current industrial 10–30 mmol L−1) is sufficient to enhance the HER Faradaic efficiency on platinum by 15%, and by co-adding 10 mmol L−1 Na2MoO4 the cathode is activated while avoiding detrimental O2 generation from chemical and electrochemical reactions. Higher concentrations of Na2MoO4 led to increased oxygen production.CONCLUSION: Careful tuning of the molybdate concentration can enhance performance of the chlorate process using chromate in the micromolar range. These insights could be also exploited in the efficient hydrogen generation by photocatalytic water splitting and in the remediation of industrial wastewater.
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- Elkafrawy, Hagar, et al.
(författare)
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Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults
- 2021
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Ingår i: Amino Acids. - : Springer Nature. - 0939-4451 .- 1438-2199. ; 53, s. 1623-1634
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Tidskriftsartikel (refereegranskat)abstract
- Plasma cysteine is associated with human obesity, but it is unknown whether this is mediated by reduced, disulfide (cystine and mixed-disulfides) or protein-bound (bCys) fractions. We investigated which cysteine fractions are associated with adiposity in vivo and if a relevant fraction influences human adipogenesis in vitro. In the current study, plasma cysteine fractions were correlated with body fat mass in 35 adults. Strong positive correlations with fat mass were observed for cystine and mixed disulfides (r >= 0.61, P < 0.001), but not the quantitatively major form, bCys. Primary human preadipocytes were differentiated in media containing cystine concentrations varying from 10-50 mu M, a range similar to that in plasma. Increasing extracellular cystine (10-50 mu M) enhanced mRNA expression of PPARG2 (to sixfold), PPARG1, PLIN1, SCD1 and CDO1 (P = 0.042- < 0.001). Adipocyte lipid accumulation and lipid-droplet size showed dose-dependent increases from lowest to highest cystine concentrations (P < 0.001), and the malonedialdehyde/total antioxidant capacity increased, suggesting increased oxidative stress. In conclusion, increased cystine concentrations, within the physiological range, are positively associated with both fat mass in healthy adults and human adipogenic differentiation in vitro. The potential role of cystine as a modifiable factor regulating human adipocyte turnover and metabolism deserves further study.
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- Kiss, Mózsi, 1982-
(författare)
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The PoGOLite balloon-borne soft gamma-ray polarimeter
- 2008
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Ingår i: Astroparticle, Particle and Space Physics, Detectors and Medical Physics Applications. - : World Scientific. - 9789812819086 ; , s. 886-890
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Konferensbidrag (refereegranskat)abstract
- PoGOLite is a balloon-borne experiment that will measure the polarization of soft gamma-rays between 25 keV and 80 keV through detection of coincident Compton scattering and absorption in a close-packed array of 217 well-type phoswich detector cells. The potential observation targets include pulsars, accreting compact objects and astrophysical jets. The polarization properties of such radiation can reveal important new information on the geometry, magnetic fields and emission mechanisms of these sources.
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- Machado, Carla G., et al.
(författare)
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Sustainability operations management : An overview of research trends
- 2012
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Ingår i: 62nd IIE Annual Conference and Expo 2012. - : Institute of Industrial Engineers. ; , s. 150-160
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Konferensbidrag (refereegranskat)abstract
- Several authors have been devoted their research projects to understand and map research topics and themes studied in the field of Industrial Engineering (IE), particularly those related to Operations Management (OM), aiming to contribute to the field scope delimitation, identifying for that purpose its main authors and their contribution for theory and practice. This study seeks to frame this knowledge regarding to sustainability research. Bibliometrics and statistics analysis were performed using information collected from 500 selected papers in nine international databases related to OM field, based on the keywords "Sustainability" and "Operations Management". Results point to a central set of nineteen authors whose work is strongly related to sustainability issues. All information are systematized generating descriptive statistics, network graphs and multivariate matrices for research topics, methodologies, outlets, main academic and normative references. Thus, this paper contributes with an overview of trends and gaps for future research in sustainability concerning operations management field.
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