| 1. |
- Arnason, Ulfur, et al.
(författare)
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Mitogenomic analyses of eutherian relationships
- 2002
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Ingår i: Cytogenetic and Genome Research. - : S. Karger AG. - 1424-859X .- 1424-8581. ; 96:1-4, s. 20-32
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Tidskriftsartikel (refereegranskat)abstract
- Reasonably correct phylogenies are fundamental to the testing of evolutionary hypotheses. Here, we present phylogenetic findings based on analyses of 67 complete mammalian mitochondrial (mt) genomes. The analyses, irrespective of whether they were performed at the amino acid (aa) level or on nucleotides (nt) of first and second codon positions, placed Erinaceomorpha (hedgehogs and their kin) as the sister group of remaining eutherians. Thus, the analyses separated Erinaceomorpha from other traditional lipotyphlans (e.g., tenrecs, moles, and shrews), making traditional Lipotyphla polyphyletic. Both the aa and nt data sets identified the two order-rich eutherian clades, the Cetferungulata (comprising Pholidota, Carnivora, Perissodactyla, Artiodactyla, and Cetacea) and the African clade (Tenrecomorpha, Macroscelidea, Tubulidentata, Hyracoidea, Proboscidea, and Sirenia). The study corroborated recent findings that have identified a sister-group relationship between Anthropoidea and Dermoptera (flying lemurs), thereby making our own order, Primates, a paraphyletic assembly. Molecular estimates using paleontologically well-established calibration points, placed the origin of most eutherian orders in Cretaceous times, 70-100 million years before present (MYBP). The same estimates place all primate divergences much earlier than traditionally believed. For example, the divergence between Homo and Pan is estimated to have taken place approximate to 10 MYBP, a dating consistent with recent findings in primate paleontology. Copyright
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| 2. |
- Barbu, Andreea, et al.
(författare)
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Pref-1 and adipokine expression inadipose tissues of GK And Zucker rats
- 2009
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Ingår i: Molecular and Cellular Endocrinology. - : Elsevier BV. - 0303-7207 .- 1872-8057. ; 299:2, s. 163-171
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Tidskriftsartikel (refereegranskat)abstract
- In view of the central role of preadipocyte factor-1, adiponectin and leptin in white adipose tissue function, the aim of the present study was to analyze the mRNA expression of these proteins and of the inflammatory markers interleukin-6 and tumor necrosis factor-α in visceral and subcutaneous fat pads of rats with different metabolic disorders. We demonstrated highly divergent expression of preadipocyte factor-1, upregulated expression of adiponectin, interleukin-6 and TNF-α mRNA in adipose tissues of the diabetic Goto Kakizaki rat compared to the obese Zucker rat. This was correlated to an increased number of large adipocytes and serum levels of adiponectin. Furthermore, in all four strains studied (as above plus Wistar Furth and Zucker Lean), significant heterogeneity was evident in adipokine expression within specific adipose tissues previously defined as belonging to the visceral or subcutaneous fat depots. These results suggest that significantly increased levels of inflammation and redistribution of adipocyte size are mechanisms contributing to the development of type 2 diabetes in the GK rat.
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| 3. |
- Choi, J H, et al.
(författare)
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Comparative study on dry etching of alpha- and beta-SiC nano-pillars
- 2012
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Ingår i: Materials letters (General ed.). - : Elsevier. - 0167-577X .- 1873-4979. ; 87, s. 9-12
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Tidskriftsartikel (refereegranskat)abstract
- Different polytypes (alpha-SiC and beta-SiC) and crystallographic orientations ((0001) and (11-20) of 6H-SiC) have been used in order to elaborate silicon carbide (SiC) nanopillars using the inductively coupled plasma etching method. The cross section of the SiC pillars shows a rhombus, pentagonal or hexagonal morphology depending on polytypes and crystallographic orientations. The favored morphologies of SiC nanopillars originate from a complex interplay between their polytypes and crystal orientations, which reflects the so-called Wulffs rule.
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| 4. |
- Colella, Gianluca
(författare)
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Proposizioni comparative ipotetiche in italiano
- 2010
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Ingår i: «Letterature Straniere &». Quaderni della Facoltà di Lingue e Letterature Straniere dell’Università degli Studi di Cagliari. - 2038-6389. ; XII, s. 57-75
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Czaika, Otfried, 1971-
(författare)
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Reiner Brockmann
- 2004
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Ingår i: Biographisches LExikon für Mecklenburg. - Rostock : SchmidtRömhild. - 3795037417 - 9783795037413 ; , s. 24-27
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 6. |
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| 7. |
- Fontes, Magnus
(författare)
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Optimal results for the nonhomogeneous initial-boundary value problem for the two-dimensional Navier-Stokes equations
- 2010
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Ingår i: Journal of Mathematical Fluid Mechanics. - : Springer Science and Business Media LLC. - 1422-6928 .- 1422-6952. ; 12, s. 412-434
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Tidskriftsartikel (refereegranskat)abstract
- In this work we study the fully nonhomogeneous initial boundary value problem for the two-dimensional time-dependent Navier–Stokes equations in a general open space domain in R2 with low regularity assumptions on the initial and the boundary value data. We show that the perturbed Navier–Stokes operator is a diffeomorphism from a suitable function space onto its own dual and as a corollary we get that the Navier–Stokes equations are uniquely solvable in these spaces and that the solution depends smoothly on all involved data. Our source data space and solution space are in complete natural duality and in this sense, without any smallness assumptions on the data, we solve the equations for data with optimally low regularity in both space and time.
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| 8. |
- Glantz, Andreas, Universitetsadjunkt, 1977-
(författare)
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Har du tid med patienter?
- 2020
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Ingår i: Psyche. - : Psykiatriska Riksföreningen för Sjuksköterskor. - 0283-3468. ; :1, s. 8-9
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Tiden som sjuksköterskor spenderar tillsammans med patienterna måste ökas för att tillitsfulla terapeutiska relationer skall kunna skapas och underhållas. Andreas Glantz, specialistsjuksköterska i psykiatrisk vård och magister i omvårdnad, verksam inom allmänpsykiatrin Region Skåne, sammanfattar sin studie om hur sjuksköterskor i psykiatrisk heldygnsvård använder sin tid.
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| 9. |
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| 10. |
- Marsell, Richard, et al.
(författare)
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Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23.
- 2008
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Ingår i: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. - : Oxford University Press (OUP). - 1460-2385 .- 0931-0509. ; 23:3, s. 827-33
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Fibroblast growth factor-23 (FGF23), a circulating protein produced in bone, causes decreased renal inorganic phosphate (Pi) reabsorption by reducing the expression of the sodium phosphate cotransporter type 2a (Npt2a). We have previously generated transgenic mice expressing human wild-type (WT) FGF23 under the control of the alpha1 (I) collagen promoter. METHODS: In this study, we performed a large-scale gene expression study of kidneys from FGF23 transgenic mice and WT littermates. Microarray expression data of key transcripts were verified by real-time RT-PCR analysis. RESULTS: Several genes that play a role in Pi regulation revealed decreased expression levels in the transgenic mice, such as Npt2a and Pdzk1, a scaffolding protein known to interact with Npt2a. Importantly, Klotho, a suggested FGF23 receptor cofactor, was the most significantly decreased transcript and alpha2-Na(+)/K(+)-ATPase (Atp1a2), a gene isoform of alpha1-Na(+)/K(+)-ATPase (Atp1a1) which has recently been shown to interact with Klotho and regulate calcium metabolism, was the most increased transcript. In contrast, other genes proposed to regulate Pi levels, such as secreted frizzled-related protein-4 (sFrp4) and Na(+)/H(+) exchanger regulatory factor-1 (Nherf1) revealed no changes. CONCLUSIONS: FGF23 transgenic mice display differentially expressed transcript levels of several genes essential in renal Pi regulation. These findings may lead to further understanding of how FGF23 mediates its actions on renal Pi regulation.
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