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1.
  • Tuominen, Mikko, et al. (författare)
  • Superamphiphobic overhang structured coating on a biobased material
  • 2016
  • Ingår i: Applied Surface Science. - : Elsevier. - 0169-4332 .- 1873-5584. ; 389, s. 135-143
  • Tidskriftsartikel (refereegranskat)abstract
    • A superamphiphobic coating on a biobased material shows extreme liquid repellency with static contact angles (CA) greater than 150 degrees and roll-off angles less than 10 degrees against water, ethylene glycol, diiodomethane and olive oil, and a CA for hexadecane greater than 130 degrees. The coating consisting of titanic nanoparticles deposited by liquid flame spray (LFS) and hydrophobized using plasma-polymerized perfluorohexane was applied to a birch hardwood. Scanning electron microscopy (SEM) imaging after sample preparation by UV laser ablation of coated areas revealed that capped structures were formed and this, together with the geometrically homogeneous wood structure, fulfilled the criteria for overhang structures to occur. The coating showed high hydrophobic durability by still being non-wetted after 500 000 water drop impacts, and this is discussed in relation to geometrical factors and wetting forces. The coating was semi-transparent with no significant coloration. A self-cleaning effect was demonstrated with both water and oil droplets. A self-cleanable, durable and highly transparent superamphiphobic coating based on a capped overhang structure has a great potential for commercial feasibility in a variety of applications, here exemplified for a biobased material.
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  • Flammini, Francesco, Senior Lecturer, 1978-, et al. (författare)
  • Multiformalism techniques for critical infrastructure modeling
  • 2010
  • Ingår i: International Journal of System of Systems Engineering. - 1748-0671 .- 1748-068X. ; 2:1, s. 19-37
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper proposes an approach to use multiformalism techniques for critical infrastructure modelling. To this aim, the state of the art of related works on the subject is surveyed and a general scheme for intra and inter infrastructure models is described. Multiformalism approaches allow modellers to adapt the choice of formal languages to the nature, complexity and abstraction layer of the subsystems to be modelled. Another advantage is the possibility of reusing existing dependability models and solvers. Complexity and heterogeneity are managed through modularity, and composition allows for representing structural or functional dependencies. An example model based on a railway infrastructure is used to illustrate the concepts introduced by the paper. Copyright © 2010 Inderscience Enterprises Ltd.
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  • Daskalakis, Kosmas, et al. (författare)
  • Anti-tumour activity of everolimus and sunitinib in neuroendocrine neoplasms
  • 2019
  • Ingår i: Endocrine Connections. - : Bioscientifica. - 2049-3614. ; 8:6, s. 641-653
  • Tidskriftsartikel (refereegranskat)abstract
    • Comparisons between everolimus and sunitinib regarding their efficacy and safety in neuroendocrine neoplasms (NENs) are scarce. We retrospectively analysed the clinicopathological characteristics and outcomes in 92 patients with well-differentiated (WD) NEN of different origin (57 pancreatic NENs (PanNENs)), treated with molecular targeted therapy (MTT) with everolimus or sunitinib, first- (73: 19) or second-line (sequential; 12: 22) for progressive disease. Disease control rates (DCR: partial response or stable disease) at first-line were higher in all patients treated with everolimus than sunitinib (64/73 vs 12/19, P = 0.012). In PanNENs, DCR at first-line everolimus was 36/42 versus 9/15 with sunitinib (P = 0.062). Progression-free survival (PFS) at first-line everolimus was longer than sunitinib (31 months (95% CI: 23.1-38.9) vs 9 months (95% CI: 0-18.5); log-rank P < 0.0001) in the whole cohort and the subset of PanNENs (log-rank P < 0.0001). Median PFS at second-line MTT was 12 months with everolimus (95% CI: 4.1-19.9) vs 13 months with sunitinib (95% CI: 9.3-16.7; log-rank P = 0.951). Treatment with sunitinib (HR: 3.47; 95% CI: 1.5-8.3; P value: 0.005), KI67 > 20% (HR: 6.38; 95% CI: 1.3-31.3; P = 0.022) and prior chemotherapy (HR: 2.71; 95% CI: 1.2-6.3; P = 0.021) were negative predictors for PFS at first line in multivariable and also confirmed at multi-state modelling analyses. Side effect (SE) analysis indicated events of serious toxicities (Grades 3 and 4: n = 13/85 for everolimus and n = 4/41 for sunitinib). Discontinuation rate due to SEs was 20/85 for everolimus versus 4/41 for sunitinib (P = 0.065). No additive toxicity of second-line MTT was confirmed. Based on these findings, and until reliable predictors of response become available, everolimus may be preferable to sunitinib when initiating MTT in progressive NENs.
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  • Zetterström, Oskar, et al. (författare)
  • Mode-matching Analysis of Loaded Transmission Lines with Twist Symmetries
  • 2020
  • Ingår i: Proceedings 14th European Conference on Antennas and Propagation (EuCAP). - : Institute of Electrical and Electronics Engineers (IEEE).
  • Konferensbidrag (refereegranskat)abstract
    • This paper studies the propagation characteristics in twist-symmetric structures by means of a mode-matching approach. The studied structures are coaxial transmission lines periodically loaded with 1- and 3-fold twist-symmetric infinitely thin sectorial sheets. The mode-matching formulation is validated with the commercial software CST Microwave Studio. In addition, the impact of adding twist symmetry to a coaxial line on the coupling of the higher order TM modes is discussed.
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