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- Lundälv, Jörgen, 1966
(författare)
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Bioterrorism och media
- 2004
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Attacker med biologiska och kemiska preparat är ett nytt hot mot institutioner i världen bl.a massmedia. I USA har ett antal medieföretag attackerats med brev som visat sig innehålla mjältbrand. I Sverige utsätts medier för hot och risker med jämna mellanrum. Denna guide om säkerhet och beredskap ger ny kunskap om vad bioterrorism innebär och vilka hotbilder som finns mot medieföretag i Sverige. Den vänder sig också till informationsstrateger vid myndigheter och företag liksom till hälso- och sjukvårdspersonal med intresse för epidemiologiska frågor. Guiden inleds med företal av Gorm Albrechtsen, f.d. chefredaktör vid Herning Folkeblad i Danmark som utsatts för misstänkta pulverbrev samt av Åke Sellström, avdelningschef vid Totalförsvarets forskningsinstitut (FOI) och expert på biologiska och kemiska vapen.
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| 2. |
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| 3. |
- Gabrielsson, Johan
(författare)
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Quantitative pharmacology : an introduction to integrative pharmacokinetic-pharmacodynamic analysis
- 2012
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- PKPD awareness is vital if we are to attempt to relate preclinical results to the acute and long term consequences in humans. The debate on whether preclinical findings can be translated to the human usage is still engaging scientists across industry, academia and regulatory bodies. Pharmacokinetics (PK) and pharmacodynamics (PD) comprise traditionally distinct disciplines within pharmacology, the study of the interaction of drugs with the body. It is our intention to show that by deliberately, intimately and systematically integrate these disciplines our understanding of drugs and the efficiency and effectiveness of drug discovery and development may be greatly enhanced. The book is therefore written with a broad audience in mind and focuses on concepts. Pharmacologists of all sorts, safety scientists, pharmacokineticists, medicinal chemists, clinicians, statisticians, veterinarians, animal science professionals, project leaders and students of medical, pharmaceutical and veterinary sciences are the primary targets.
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| 6. |
- Yadav, Vikas
(författare)
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Antimicrobial Peptides & Leucine Zipper Motif: A legitimate affair in quest of best antibiotic drug
- 2019
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Antimicrobial peptides have emerged as a novel class of therapeutic molecules in recent decades as they exhibit broad-spectrum activity against a variety of Gram-positive, Gram-negative bacteria, fungi and tumor cells. Antimicrobial peptides are nature’s antibiotics that are conserved throughout the evolution. They have an advantage over conventional antibiotics as they target the cell membrane of the pathogen and disrupt its integrity which gives very little scope for the bacteria to develop resistance against these peptides. These peptides serve as the first line of defense against intruding pathogens. However, utilization of peptides as an antibiotic outside their natural host needs explicit understanding about the mechanism of action owing to their cytotoxicity against mammalian cells. Precise knowledge about the mechanism of action and structure-activity relationship will aid in designing novel antimicrobial peptide-based therapeutics. Therefore this book describes the basics of antimicrobial peptides and illustrates the experimental work done for identification of factors involved in their toxicity towards mammalian cells.
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