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Träfflista för sökning "AMNE:(MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology) ;lar1:(ltu)"

Sökning: AMNE:(MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology) > Luleå tekniska universitet

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1.
  • Ponsot, Elodie, 1973-, et al. (författare)
  • Skeletal muscle telomere length is not impaired in healthy physically active old women and men
  • 2008
  • Ingår i: Muscle and Nerve. - : Wiley. - 0148-639X .- 1097-4598. ; 37:4, s. 467-472
  • Tidskriftsartikel (refereegranskat)abstract
    • We have previously shown that the number of satellite cells is lower in old than young men and women. The aim of this study was to further explore the effects of aging on the regenerative potential of skeletal muscle in 16 young and 26 old men and women with comparable physical activity level (young, 25 +/- 4 years; old, 75 +/- 4 years). Mean and minimum telomere lengths were determined using Southern blot analyses on biopsies obtained from the tibialis anterior muscle. There were no significant age or gender effects on mean and minimal telomeric lengths, suggesting that the replicative potential in the remaining satellite cells in the tibialis anterior muscle is not impaired with increasing age and the existence of in vivo regulatory mechanisms allowing the maintenance of telomere length. These results imply that moderate physical activity regularly performed by old subjects is not associated with accelerated telomere loss.
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2.
  • Kassberg, Ann-Charlotte, et al. (författare)
  • Ability to manage everyday technology after acquired brain injury
  • 2013
  • Ingår i: Brain Injury. - : Informa UK Limited. - 0269-9052 .- 1362-301X. ; 27:13-14, s. 1583-1588
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: To investigate and describe how persons with an acquired brain injury (ABI) manage everyday technology (ET) in their daily activities and to explore whether the ability to manage ET was related to the severity of the disability. Method: Eighty-one persons with ABI were observed while managing ET by using the Management of Everyday Technology Assessment (META). The Glasgow Outcome Scale-Extended (GOSE) was used to assess the severity of disability after the ABI. A computer application of a Rasch measurement model was used to generate measures of the participants’ ability to manage ET and the measures were compared groupwise with analysis of covariance (ANCOVA). Results: The degree of severity of disability had a significant main effect on the ability to manage ET. The groups with severe and moderate disability exhibited a significantly lower ability to manage ET compared to the group with good recovery. Conclusion: The result indicates that the ability to manage ET in daily activities can be related to the global severity of disability after ABI. This demonstrates the importance of considering the ability to manage ET to support the performance of activities at home, at work and in society in persons with ABI.
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3.
  • Gard, Anna, et al. (författare)
  • Quality of life of ice hockey players after retirement due to concussions
  • 2020
  • Ingår i: Concussion. - : Future Medicine. - 2056-3299. ; 5:3
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Sports-related concussion (SRC) is increasingly recognized as a potential health problem in ice hockey. Quality of life (QoL) in players retiring due to SRC has not been thoroughly addressed. Materials & methods: QoL using the Sports Concussion Assessment Tool 5th Edition, Impact of Event Scale-Revised and Short Form Health Survey was measured in Swedish ice hockey players who retired due to persistence of postconcussion symptoms or fear of attaining additional SRC. Results: A total of 76 players were assessed, on average of 5 years after their most recent SRC. Overall, retired players had a high burden of postconcussion symptoms and reduced QoL. Conclusion: Retired concussed ice hockey players have a reduced QoL, particularly those retiring due to postconcussion symptoms. Symptom burden should be continuously evaluated and guide the decision to retire.
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4.
  • Vedung, Fredrik, et al. (författare)
  • Concussion incidence and recovery in Swedish elite soccer : prolonged recovery in female players
  • 2020
  • Ingår i: Scandinavian Journal of Medicine and Science in Sports. - : John Wiley & Sons. - 0905-7188 .- 1600-0838. ; 30:5, s. 947-957
  • Tidskriftsartikel (refereegranskat)abstract
    • ObjectivesSport‐related concussions are an increasingly recognized health problem. Soccer is the most popular sport in the world although recent studies on concussion incidence are scarce. Here, a nation‐wide prospective study on concussion incidence, symptom severity, risk factors, gender differences and return‐to‐play after concussion was performed in 51 Swedish elite soccer teams during the 2017 season.MethodsIn the first and second soccer leagues for men and women, a Sport Concussion Assessment Tool (SCAT) ‐based questionnaire study was performed at pre‐season (baseline) and from 48h up to three months post‐concussion.ResultsWe followed 959 players (389 women, 570 men) for 25146 player game hours (9867 h for women, 15279 h for men). Concussion incidence (n= 36) was 1.19/1000 player game hours (females 1.22/1000 h, males 1.18/1000 h; p= 0.85). Twenty‐seven percent (females 8%, males 40%) of players continued to play immediately after the concussion. When compared to male players, female players had worse initial symptom severity scores (median and IQR 30 (17‐50.5) vs. 11 (4‐26.25), p=0.02) and longer return to play (p=0.02). Risk factors for concussion were baseline symptoms and previous concussion.ConclusionIn Swedish elite soccer, the concussion incidence was 1.19/1000 without gender differences. Most players recovered to play within four weeks post‐injury. Almost one third of players continued to play at time of concussion. Female players had worse initial symptoms and longer return‐to‐play time than males, and a prolonged recovery beyond three months was only observed among female players.
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6.
  • Engström, Åsa, et al. (författare)
  • Losing the identity of a hockey player : the long-term effects of concussions
  • 2020
  • Ingår i: Concussion. - : Future Medicine. - 2056-3299. ; 5:2
  • Tidskriftsartikel (refereegranskat)abstract
    • Aim: To describe what suffering multiple concussions meant for former semi-professional or professional hockey players who were forced to end their career. Results: Nine former Swedish hockey players, who once played on national or professional teams were interviewed. The interviews were analyzed with reference to hermeneutic phenomenology to interpret and explain their experiences. The theme of losing one’s identity as a hockey player was constructed from five subthemes: being limited in everyday life, returning to the hockey stadium as soon as possible, forming a post career identity, lacking understanding and support, and preventing injuries by respecting other players. Conclusion: The former hockey players struggled with developing their off-the-ice identities and with finding other sources of meaning for their lives.Lay abstractDespite considerable attention to improving the initial management of concussions suffered by hockey players, few studies have examined their long-term effects. In response, the study reported here aimed to describe what suffering multiple concussions meant for former semi-professional or professional hockey players who were forced to end their career. Nine former Swedish hockey players, who once played on national or professional teams were interviewed and the interviews were analyzed in order to interpret and explain their experiences. The overall theme was formulated as losing one’s identity as a hockey player. In conclusion, the former hockey players seem to struggle with developing their off-the-ice identities and with finding other sources of meaning for their lives.
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7.
  • Walton, Lois, et al. (författare)
  • The Effects of Working Memory Updating Training in Parkinson's Disease : A Feasibility and Single-Subject Study on Cognition, Movement and Functional Brain Response
  • 2021
  • Ingår i: Frontiers in Psychology. - : Frontiers Media S.A.. - 1664-1078. ; 11
  • Tidskriftsartikel (refereegranskat)abstract
    • In Parkinson's disease (PD), the fronto-striatal network is involved in motor and cognitive symptoms. Working memory (WM) updating training engages this network in healthy populations, as observed by improved cognitive performance and increased striatal BOLD signal. This two-part study aimed to assess the feasibility of WM updating training in PD and measure change in cognition, movement and functional brain response in one individual with PD after WM updating training. A feasibility and single-subject (FL) study were performed in which patients with PD completed computerized WM updating training. The outcome measures were the pre-post changes in criterion and transfer cognitive tests; cognitive complaints; psychological health; movement kinematics; and task-related BOLD signal. Participants in the feasibility study showed improvements on the criterion tests at post-test. FL displayed the largest improvements on the criterion tests and smaller improvements on transfer tests. Furthermore, FL reported improved cognitive performance in everyday life. A shorter onset latency and smoother upper-limb goal-directed movements were measured at post-test, as well as increased activation within the striatum and decreased activation throughout the fronto-parietal WM network. This two-part study demonstrated that WM updating training is feasible to complete for PD patients and that change occurred in FL at post-test in the domains of cognition, movement and functional brain response.
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8.
  • Brogårdh, Christina, et al. (författare)
  • Construct Validity of a New Rating Scale for Self-Reported Impairments in Persons With Late Effects of Polio.
  • 2013
  • Ingår i: PM & R : the journal of injury, function, and rehabilitation. - : Wiley. - 1934-1563 .- 1934-1482. ; 5:3, s. 176-181
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: To evaluate the construct validity of a new rating scale for self-reported impairments in persons with late effects of polio. DESIGN: Psychometric analysis of data on self-perceived impairments in persons with prior polio. PARTICIPANTS: Two hundred and seventy-three persons with prior polio (119 men and 154 women; mean age, 63.5 years). METHOD: Rasch analysis of a 13-item rating scale with 5 response categories, in which the participants rated how much they have been bothered by various post-polio-related impairments during the past 2 weeks. RESULTS: The initial analysis showed disordered categories, misfit with some of the items, multidimensionality, and local dependency. After adjustment of the categories, which resulted in a 4-category rating scale, fit to the model was achieved, but the scale still showed signs of multidimensionality. Analyses of local dependency revealed correlations among some of the items, which resulted in a 5 testlet solution, which gave fit to the model and unidimensionality. CONCLUSION: After adjustment of the categories and local dependency, this new rating scale, Self-Reported Impairments in Persons With Late Effects of Polio, can be considered as unidimensional. The good psychometric properties implies that the Self-Reported Impairments in Persons With Late Effects of Polio scale could be a useful rating scale that would increase our understanding of the impairments that persons with late effects of polio can experience. With further refinements, this scale may assist in the planning and evaluation of appropriate rehabilitation interventions.
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9.
  • Lexell, Jan, et al. (författare)
  • Psychometric Properties of Three Fatigue Rating Scales in Individuals With Late Effects of Polio
  • 2018
  • Ingår i: Annals of Rehabilitation Medicine. - : Korean Academy of Rehabilitation Medicine. - 2234-0645 .- 2234-0653. ; 42:5, s. 702-712
  • Tidskriftsartikel (refereegranskat)abstract
    • ObjectiveTo evaluate the psychometric properties of the Fatigue Severity Scale (FSS), the Fatigue Impact Scale (FIS), and the Multidimensional Fatigue Inventory (MFI-20) in persons with late effects of polio (LEoP). More specifically, we explored the data completeness, scaling assumptions, targeting, reliability, and convergent validity.MethodsA postal survey including FSS, FIS, and MFI-20 was administered to 77 persons with LEoP. Responders received a second survey after 3 weeks to enable test-retest reliability analyses.ResultsSixty-one persons (mean age, 68 years; 54% women) responded to the survey (response rate 79%). Data quality of the rating scales was high (with 0%–0.5% missing item responses), the corrected item-total correlations exceeded 0.4 and the scales showed very little floor or ceiling effects (0%–6.6%). All scales had an acceptable reliability (Cronbach’s α ≥0.95) and test-retest reliability (intraclass correlation coefficient, ≥0.80). The standard error of measurement and the smallest detectable difference were 7%–10% and 20%–28% of the possible scoring range. All three scales were highly correlated (Spearman’s correlation coefficient rs=0.79–0.80; p<0.001).ConclusionThe FSS, FIS, and MFI-20 exhibit sound psychometric properties in terms of data completeness, scaling assumptions, targeting, reliability, and convergent validity, suggesting that these three rating scales can be used to assess fatigue in persons with LEoP. As FSS has fewer items and therefore is less time consuming it may be the preferred scale. However, the choice of scale depends on the research question and the study design.
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10.
  • Lexell, Jan, et al. (författare)
  • Idrott och skallskador : riktlinjer för omhändertagande och återgång till träning och tävling
  • 2000
  • Ingår i: Läkartidningen. - 0023-7205 .- 1652-7518. ; 97:43, s. 4848-53
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • Head injuries in sports have received increased attention during the past decade. As explained in this article, the most recent guidelines for the management of head injuries in sports adopted by the American Academy of Neurology (AAN) have been adapted for the Swedish sports society. The guidelines include a grading scale of head injuries in sports, a sideline evaluation to aid physicians, coaches and athletes in the acute situation, and a management strategy for safe return to play after a head injury. The use of these guidelines will facilitate appropriate acute and subacute management and thereby prevent repeated head injuries that could lead to potentially catastrophic outcome or long-term cognitive sequelae
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