| 1. |
- Cutas, Daniela, 1978, et al.
(författare)
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Legal imperialism in the regulation of stem cell research and therapy: the problem of extraterritorial jurisdiction
- 2010
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Ingår i: Capps BJ & Campbell AV (eds.). CONTESTED CELLS: Global Perspectives on the Stem Cell Debate. - London : Imperial College Press. - 9781848164376 ; , s. 95-119
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Countries worldwide have very different national regulations on human embryonic stem (ES) cell research, informed by a range of ethical values. Some countries find reason to extend the applicability of their regulations on such research to its citizens when they visit other countries. Extraterritorial jurisdiction has recently been identified as a potential challenge towards global regulation of ES cell research. This chapter explores the implications and impact of extraterritorial jurisdiction and global regulation of ES cell research on researchers, clinicians and national health systems, and how this may affect patients. The authors argue that it would make ethical sense for ES cell restrictive countries to extend its regulations on ES cell research beyond its borders, because, if these countries really consider embryo destruction to be objectionable on the basis on the status of the embryo, then they ought to count it morally on par with murder (and thus have a moral imperative to protect embryos from the actions of its own citizens). However, doing so could lead to a legal situation that would result in substantial harm to central values in areas besides research, such as health care, the job market, basic freedom of movement, and strategic international finance and politics. Thus, it seems that restrictive extraterritorial jurisdiction in respect to ES cell research would be deeply problematic, given that the ethical permissibility of ES cell research is characterised by deep and wide disagreement.
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| 2. |
- Falk Erhag, Hanna, et al.
(författare)
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Concluding Remarks
- 2022
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Ingår i: A Multidisciplinary Approach to Capability in Age and Ageing. - Chem : Springer. - 9783030780654 ; 18:2, s. 143-144
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 3. |
- Munthe, Christian, 1962
(författare)
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Precautionary Principle
- 2013
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Ingår i: International Encyclopedia of Ethics. - Chichester : Blackwell. - 9781444367072
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Bokkapitel (refereegranskat)abstract
- Following the statement in the United Nations' Rio Declaration of 1992 that countries should apply a “precautionary approach” in policymaking on environmental and technological issues, the notion of a precautionary principle (PP) has gained ground in worldwide policymaking and regulation, thus catching the interest of ethics scholars. Although seldom explained in much detail, and resulting in quite different policy results in different countries and areas (O'Riordan et al. 2001; Sandin 1999; Trouwborst 2002; Zander 2010), PP is generally understood as a norm urging or permitting policymakers to take preventive action in the face of unknown, uncertain, or probable dangers, motivated by the experience of how seemingly valuable and promising practices may lead to seriously adverse consequences in spite of lack of solid evidence to this effect (Sandin 1999). In ethics debate, this idea has been applied not only to matters regarding the large-scale introduction and use of technology (e.g., regarding energy production, transport and communication, nano- or biotechnology, and so on) (see Biotechnology; Nanotechnology, Ethics of) with possible ensuing impact on the natural environment connecting to the notion of sustainability (see Sustainability), but also, for example, to abortion (see Abortion), medical genetics, embryo experimentation (see Embryo Research), the treatment of animals (see Animal Experimentation), terrorism (see Terrorism), and general research ethics (see Research Ethics) (Munthe 2011). Many of these applications advocate strong conclusions in spite of the fact that PP or its normative justification have not been made very clear. At the same time, PP has been the subject of criticism, much of which boils down to three points: lack of clarity, lack of practicality, and/or ethical implausibility. Curiously, these critical points have often been made in conjunction, in spite of the fact that a clear sense of what PP means seems necessary for backing up the other two objections.
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| 4. |
- Munthe, Christian, 1962
(författare)
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Precautionary Principle
- 2015
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Ingår i: Encyclopedia of Global Bioethics. - Dordrecht : Springer. - 9783319055442
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Bokkapitel (refereegranskat)abstract
- Precautionary reasoning has deep historical and wide cross-cultural roots in the ethics of health, health care, and medical research. As in general ethics, however, this side of bioethical thinking has not been the subject of focused critical analysis until recently. The emergence of the precautionary principle (PP) in general environmental and technology policy debate has, after an initial period of confusion, resulted in a range of possible ideas about the value of precaution and what sacrifices it may be worth. This has indicated some need for developments in ethical as well as decision theory. In bioethical debates, this process has left only vague traces, however. Although many issues exist where precautionary reasoning has a place, this is either often left unnoticed or arguments developed suffer from elementary flaws. Environmental and general public health ethics, the ethics of evidence-based practice in research, as well as clinical decision-making, management of normative or factual uncertainty, and the nature of clinical ethical virtues are all areas where precautionary ideas seem to have a place. Such reasoning moreover has specific relevance for global approaches to bioethics and health policy issues in a number of ways.
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| 5. |
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| 6. |
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| 7. |
- Wasén, Kristian, 1980
(författare)
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Introduction
- 2013
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Ingår i: Emerging Health Technology: Relocation of Innovative Knowledge and Expertise. / Kristian Wasén, editor. - Heidelberg : Springer. - 9783642325694 ; , s. 1-20.
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Bokkapitel (refereegranskat)abstract
- The opening chapter addresses the different ways in which visual knowledge and medical health expertise are being reorganised and relocated and thereby reinforced and disputed in new practices of professional work involving state-of-the-art health technology. Change management and related concepts are discussed and defined. The chapter shows that emerging health technologies, organisational renewal, and the discovery of unexpected innovative knowledge are highly interconnected in professional practice. Emerging health technology refers both to new work, physical devices, and visual knowledge and expertise that, when located and relocated in the institutional landscape—or combined and recombined in health practices—may unfold unexpectedly into new patient-doctor constellations and organisational structures.
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| 8. |
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| 9. |
- Patrignani, Norberto
(författare)
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From computer ethics to future (and information) ethics : The challenge of Nano-Bots
- 2014
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Ingår i: Ethical dimensions of bio-nanotechnology. - Hershey, PA, USA : IGI Global. - 9781466618947
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Bokkapitel (refereegranskat)abstract
- One of the emerging technologies that is getting a lot of attention is nano-technology. In particular,in this area, the convergence of research fields of biotechnology, information technology, nanotechnologyand neuroscience (or cognitive science) is introducing nano-robots, or nano-bots. These machines promise to lead to the development of a large number potential applications in medicine,but at the same time they raise also a lot of social and ethical issues. This chapter introduces severalways to start an ethical reflection in relation to nano-bots. The traditional "computer ethics"approach and the new "future ethics" proposition are both discussed and applied to this technology.The challenges introduced by nano-bots are so complex that it is possible that the application of thePrecautionary Principle would be required. A further ethical analysis of nano-bots applications inmedicine may benefit from new methodologies and strategies such as the stakeholders' network andFloridi's "entropy (the evil of Infosphere)" concept.
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| 10. |
- Skrekas, Christos, 1990, et al.
(författare)
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Fluorescence-Activated Cell Sorting as a Tool for Recombinant Strain Screening
- 2022
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Ingår i: Methods in Molecular Biology. - New York, NY : Springer US. - 1940-6029 .- 1064-3745. ; , s. 39-57
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Metabolic engineering of microbial cells is the discipline of optimizing microbial metabolism to enable and improve the production of target molecules ranging from biofuels and chemical building blocks to high-value pharmaceuticals. The advances in genetic engineering have eased the construction of highly engineered microbial strains and the generation of genetic libraries. Intracellular metabolite-responsive biosensors facilitate high-throughput screening of these libraries by connecting the levels of a metabolite of interest to a fluorescence output. Fluorescent-activated cell sorting (FACS) enables the isolation of highly fluorescent single cells and thus genotypes that produce higher levels of the metabolite of interest. Here, we describe a high-throughput screening method for recombinant yeast strain screening based on intracellular biosensors and FACS.
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