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- Zöller, Bengt, et al.
(author)
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Association of irritable bowel syndrome and venous thromboembolism
- 2018
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In: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 1502-7708 .- 0036-5521. ; 53:7, s. 784-789
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Journal article (peer-reviewed)abstract
- OBJECTIVE: Inflammatory bowel disease (IBD) is associated with venous thromboembolism (VTE). Whether functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), are associated with VTE has not been determined. This nationwide study aimed to determine the risk of VTE in IBS outpatients in primary and specialist care.DESIGN: We performed two matched case-control studies. Cases (n = 90,502) were individuals in Sweden aged 18-80 years with a first hospital diagnosis of VTE between 2001 and 2010. Five controls (n = 452,510) from the Swedish Total Population Register were matched to each case for birth, sex, country of birth, and education level. Diagnosis of IBS was determined in the Swedish hospital outpatient register. This procedure was replicated for the primary care population. As the Primary Care data did not have nationwide coverage, we only included individuals that were registered in the Primary Care database. A total of 9766 cases of hospital diagnosed VTE individuals could be found in the Primary Care population and they were matched to 48,830 controls also from the Primary health care population. Conditional logistic regression was used to determine odds ratio (OR) for first VTE diagnosis. Results The adjusted OR for VTE when IBS was diagnosed in hospital outpatient care was 1.49 (95% confidence interval 1.33-1.67). The crude OR for VTE was 1.18 (0.94-1.48) when IBS was diagnosed in primary care.CONCLUSIONS: This is the first study describing an association between VTE and IBS. The results suggest that specialist treated IBS patients have increased risk of VTE.
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| 3. |
- Edgerton, Michael
(author)
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The 21st Century Voice, 2nd edition. Rowman & Littlefield (324 pp.). Lanham: MD, December 2014. : Contemporary and Traditional Extra-Normal Voice
- 2014. - 2nd
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Book (peer-reviewed)abstract
- In The 21st-Century Voice: Contemporary and Traditional Extra-Normal Voice, Michael Edward Edgerton considers contemporary vocal techniques within an acoustic and anatomical framework. Throughout, he proposes new directions for vocal exploration. Much more than a historical treatise on 20th-century masterworks or vocal science, The 21st-Century Voice explores experimental methods of sound production, offering a systematic series of approaches and methods for assessing, engaging, and, in some instances, overcoming the assumed limits of vocal singing.Appearing a decade after the publication of the first edition, this second edition draws on and advances our current understandings of voice production. Divided into four parts—air flow, source, resonance/articulation, and heightened potentials—Edgerton considers crucial matters affecting vocal production, such as: Registral challenges Filtering Airflow modification Combinatorial, multiphonic principles Extreme voice possibilities Multidimensional vocal issuesWith more than 250 illustrations, 150 associated audio tracks, an extended appendix on voice science, a glossary of key terms, and lists of representative compositions, The 21st-Century Voice will appeal to composers and performers interested in exploring the ever-broadening range of vocal possibilities. Its engagement with the complexities of vocal production should also be relevant to students and scholars of voice science, acoustics, linguistics, computer modeling, and more.
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