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Regional variation in quality of life in patients with a Fontan circulation: A multinational perspective

Fogleman, Nicholas D. (author)
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Apers, Silke (author)
KU Leuven Department of Public Health and Primary Care, Leuven, Belgium
Moons, Philip, 1968 (author)
Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences,KU Leuven Department of Public Health and Primary Care, Leuven, Belgium
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Morrison, Stacey (author)
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Wittekind, Samuel G. (author)
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Tomlin, Martha (author)
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Gosney, Kathy (author)
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Sluman, Maayke A. (author)
Academic Medical Center, Department of Cardiology, Amsterdam, the Netherlands
Johansson, Bengt (author)
University Hospital of Umeå, Umeå, Sweden
Enomoto, Junko (author)
Department of Adult Congenital Heart Disease, Chiba Cardiovascular Center, Chiba, Japan
Dellborg, Mikael, 1954 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine,The Sahlgrenska Academy at University of Gothenburg, Institute of Health and Care Sciences, Gothenburg, Sweden
Lu, Chun Wei (author)
Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
Subramanyan, Raghavan (author)
Frontier Lifeline Hospital, Dr. K. M. Cherian Heart Foundation, Chennai, India.
Luyckx, Koen (author)
School Psychology and Child and Adolescent Development, KU Leuven, Leuven, Belgium
Budts, Werner (author)
Division of Congenital and Structural Cardiology, University Hospitals Leuven, Leuven, Belgium
Jackson, Jamie (author)
Columbus Ohio Adult Congenital Heart Disease Program, Nationwide Children's Hospital, The Ohio State College of Medicine, Columbus, OH
Kovacs, Adrienne (author)
Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada
Soufi, Alexandra (author)
Hospital Louis Pradel, Lyon, France
Eriksen, Katrine (author)
Oslo University Hospital, Rikshospitalet, Oslo, Norway
Thomet, Corina (author)
Center for Congenital Heart Disease, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
Berghammer, Malin, 1970 (author)
Högskolan Väst,Gothenburg University,Göteborgs universitet,Centrum för personcentrerad vård vid Göteborgs universitet (GPCC),University of Gothenburg Centre for person-centred care (GPCC),Avdelningen för omvårdnad - avancerad nivå,University of Gothenburg, Centre for Person-Centred Care (GPCC), Gothenburg, Sweden
Callus, Edward (author)
Clinical Psychology Services IRCCS Policlinico San Donato, Milan, Italy
Fernandes, Susan M. (author)
Stanford Hospital and Clinics, Stanford, CA
Caruana, Maryanne (author)
Department of Cardiology, Mater Dei Hospital, Msida, Malta
Cook, Stephen C. (author)
Adult Congenital Heart Disease Center, Heart Institute, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
Mackie, Andrew S. (author)
University of Alberta, Edmonton, Alberta, Canada
White, Kamila S. (author)
Washington University and Barnes Jewish Heart & Vascular Center, and University of Missouri, Saint Louis, MO
Khairy, Paul (author)
Congenital Heart Center, Montreal Heart Institute, Montreal, Quebec, Canada
Kutty, Shelby (author)
University of Nebraska Medical Center/Children's Hospital and Medical Center, Omaha, NE
Veldtman, Gruschen (author)
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
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 (creator_code:org_t)
Elsevier BV, 2017
2017
English.
In: American Heart Journal. - : Elsevier BV. - 0002-8703 .- 1097-6744. ; 193, s. 55-62
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • © 2017 Elsevier Inc. Background Impaired quality of life (QOL) is associated with congenital heart disease (CHD) and country of residence; however, few studies have compared QOL in patients with differing complexities of CHD across regional populations. The current study examined regional variation in QOL outcomes in a large multinational sample of patients with a Fontan relative to patients with atrial septal defects (ASDs) and ventricular septal defects (VSDs). Methods From the Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease—International Study (APPROACH-IS), 405 patients (163 Fontan and 242 ASD/VSD) across Asia, Europe, and North America provided consent for access to their medical records and completed a survey evaluating QOL (0 to 100 linear analog scale). Primary CHD diagnosis, disease complexity, surgical history, and documented history of mood and anxiety disorders were recorded. Differences in QOL, medical complications, and mood and anxiety disorders between Fontan and ASD/VSD patients, and across geographic regions, were examined using analysis of covariance. Hierarchical regression analyses were conducted to identify variables associated with the QOL ratings. Results Patients with a Fontan reported significantly lower QOL, and greater medical complications and mood and anxiety disorders relative to patients with ASD/VSD. Inpatient cardiac admissions, mood disorders, and anxiety disorders were associated with lower QOL among patients with a Fontan, and mood disorders were associated with lower QOL among patients with ASD/VSD. Regional differences for QOL were not observed in patients with a Fontan; however, significant differences were identified in patients with ASD/VSD. Conclusions Regional variation of QOL is commonplace in adults with CHD; however, it appears affected by greater disease burden. Among patients with a Fontan, regional variation of QOL is lost. Specific attempts to screen for QOL and mood and anxiety disorders among CHD patients may improve the care of patients with the greatest disease burden.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Omvårdnad (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nursing (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences (hsv//eng)

Keyword

Vårdvetenskap

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