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Träfflista för sökning "L773:0028 3878 OR L773:1526 632X ;pers:(Hampel H.)"

Search: L773:0028 3878 OR L773:1526 632X > Hampel H.

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  • Mattsson, Niklas, 1979, et al. (author)
  • Age and diagnostic performance of Alzheimer disease CSF biomarkers.
  • 2012
  • In: Neurology. - : American Academy of Neurology (AAN). - 1526-632X .- 0028-3878. ; 78:7, s. 468-76
  • Journal article (peer-reviewed)abstract
    • Core CSF changes in Alzheimer disease (AD) are decreased amyloid β(1-42), increased total tau, and increased phospho-tau, probably indicating amyloid plaque accumulation, axonal degeneration, and tangle pathology, respectively. These biomarkers identify AD already at the predementia stage, but their diagnostic performance might be affected by age-dependent increase of AD-type brain pathology in cognitively unaffected elderly.
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  • Vos, S. J. B., et al. (author)
  • Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCI
  • 2013
  • In: Neurology. - 0028-3878 .- 1526-632X. ; 80:12, s. 1124-1132
  • Journal article (peer-reviewed)abstract
    • Objective: To compare the predictive accuracy of beta-amyloid (A beta)1-42 and total tau in CSF, Methods: We selected 399 subjects with aMCI and 226 subjects with naMCI from a multicenter Results: At least 1 follow-up was available for 538 subjects (86%). One hundred thirty-two subjects with Conclusions: AD biomarkers are useful to predict AD-type dementia in subjects with aMCI and naMCI.
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  • Result 1-5 of 5

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