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Sökning: L773:0954 5794 > Örebro universitet

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1.
  • Allegrini, Andrea G, et al. (författare)
  • Gene × Environment contributions to autonomic stress reactivity in youth
  • 2019
  • Ingår i: Development and psychopathology (Print). - : Cambridge University Press. - 0954-5794 .- 1469-2198. ; 31:1, s. 293-307
  • Tidskriftsartikel (refereegranskat)abstract
    • Dysregulated physiological stress reactivity has been suggested to impact the development of children and adolescents with important health consequences throughout the life span. Both environmental adversity and genetic predispositions can lead to physiological imbalances in stress systems, which in turn lead to developmental differences. We investigated genetic and environmental contributions to autonomic nervous system reactivity to a psychosocial stressor. Furthermore, we tested whether these effects were consistent with the differential susceptibility framework. Composite measures of adverse life events combined with socioeconomic status were constructed. Effects of these adversity scores in interaction with a polygenic score summarizing six genetic variants, which were hypothesized to work as susceptibility factors, were tested on autonomic nervous system measures as indexed by heart rate and heart rate variability. Results showed that carriers of more genetic variants and exposed to high adversity manifested enhanced heart rate variability reactivity to a psychosocial stressor compared to carriers of fewer genetic variants. Conversely, the stress procedure elicited a more moderate response in these individuals compared to carriers of fewer variants when adversity was low.
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2.
  • Baker, Laura, et al. (författare)
  • Resting heart rate and the development of antisocial behavior from age 9 to 14 : genetic and environmental influences
  • 2009
  • Ingår i: Development and psychopathology (Print). - 0954-5794 .- 1469-2198. ; 21:3, s. 939-960
  • Tidskriftsartikel (refereegranskat)abstract
    • The genetic and environmental basis of a well-replicated association between antisocial behavior (ASB) and resting heart rate was investigated in a longitudinal twin study, based on two measurements between the ages of 9 and 14 years. ASB was defined as a broad continuum of externalizing behavior problems, assessed at each occasion through a composite measure based on parent ratings of trait aggression, delinquent behaviors, and psychopathic traits in their children. Parent ratings of ASB significantly decreased across age from childhood to early adolescence, although latent growth models indicated significant variation and twin similarity in the growth patterns, which were explained almost entirely by genetic influences. Resting heart rate at age 9-10 years old was inversely related to levels of ASB but not change patterns of ASB across age or occasions. Biometrical analyses indicated significant genetic influences on heart rate during childhood, as well as ASB throughout development from age 9 to 14. Both level and slope variation were significantly influenced by genetic factors. Of importance, the low resting heart rate and ASB association was significantly and entirely explained by their genetic covariation, although the heritable component of heart rate explained only a small portion (1-4%) of the substantial genetic variance in ASB. Although the effect size is small, children with low resting heart rate appear to be genetically predisposed toward externalizing behavior problems as early as age 9 years old.
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3.
  • Bergman, Lars R., et al. (författare)
  • Types and continua in developmental psychopathology : problem behaviors in school and their relationship to later antisocial behavior
  • 2009
  • Ingår i: Development and psychopathology (Print). - Cambridge : Cambridge University Press. - 0954-5794 .- 1469-2198. ; 21:3, s. 975-992
  • Tidskriftsartikel (refereegranskat)abstract
    • In the study of developmental psychopathology a dimensional, variable-oriented approach dominates over a typological approach. With the person-oriented research paradigm providing the metatheoretical framework, pros and cons of these two approaches are discussed, and it is pointed to different methodological realizations of the typological approach, and to the contexts where they might be appropriate. It is also pointed out that the two important and underused concepts of equifinality and multifinality with advantage can be incorporated in a person-oriented approach. An empirical example is given of the study of the structure of early adolescent problem behaviors and their relationship to later criminality where dimensional as well as typological analyses are carried out. The usefulness of the typological approach in studying the development and early manifestations of the personality disorder psychopathy is also discussed. It is concluded that the usefulness of a typological approach appears to be underestimated.
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4.
  • Bertoldi, Bridget M., et al. (författare)
  • Pursuing the developmental aims of the triarchic model of psychopathy : Creation and validation of triarchic scales for use in the USC
  • 2022
  • Ingår i: Development and psychopathology (Print). - : Cambridge University Press. - 0954-5794 .- 1469-2198. ; 34:3, s. 1088-1103
  • Tidskriftsartikel (refereegranskat)abstract
    • The triarchic model was advanced as an integrative, trait-based framework for investigating psychopathy using different assessment methods and across developmental periods. Recent research has shown that the triarchic traits of boldness, meanness, and disinhibition can be operationalized effectively in youth, but longitudinal research is needed to realize the model's potential to advance developmental understanding of psychopathy. We report on the creation and validation of scale measures of the triarchic traits using questionnaire items available in the University of Southern California Risk Factors for Antisocial Behavior (RFAB) project, a large-scale longitudinal study of the development of antisocial behavior that includes measures from multiple modalities (self-report, informant rating, clinical-diagnostic, task-behavioral, physiological). Using a construct-rating and psychometric refinement approach, we developed triarchic scales that showed acceptable reliability, expected intercorrelations, and good temporal stability. The scales showed theory-consistent relations with external criteria including measures of psychopathy, internalizing/externalizing psychopathology, antisocial behavior, and substance use. Findings demonstrate the viability of measuring triarchic traits in the RFAB sample, extend the known nomological network of these traits into the developmental realm, and provide a foundation for follow-up studies examining the etiology of psychopathic traits and their relations with multimodal measures of cognitive-affective function and proneness to clinical problems.
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5.
  • Bowen, Francois, et al. (författare)
  • Childhood internalizing problems : prediction from kindergarten, effect of maternal overprotectiveness, and sex differences
  • 1995
  • Ingår i: Development and psychopathology (Print). - : Cambridge University Press. - 0954-5794 .- 1469-2198. ; 7:3, s. 481-498
  • Tidskriftsartikel (refereegranskat)abstract
    • Used kindergarten teacher-rated anxiety-withdrawal, peer-rated popularity and shyness, and mother-rated adaptability to predict 5th-grade teacher-, peer-, and self-rated internalizing problems in 144 boys and 125 girls. The effect of maternal overprotectiveness (OP) as a moderator between kindergarten variables and 5th-grade outcomes was also examined. Kindergarten peer-rated low popularity was the best predictor of later internalizing problems for boys and girls, followed by peer-rated shyness for boys and teacher-rated anxiety-withdrawal for girls. Moderating effects of maternal OP were found only for boys. Maternal OP moderated the relation between kindergarten popularity and teacher-rated anxiety-withdrawal and 5th-grade teacher-rated anxiety-withdrawal for boys. Unpopular, anxious-withdrawn boys were more likely to be seen later by their teachers as anxious-withdrawn if their mothers were nonoverprotective.
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6.
  • Chan, Elizabeth S. M., et al. (författare)
  • Triarchic traits as risk versus protective factors for ADHD symptomatology : A prospective longitudinal investigation
  • 2024
  • Ingår i: Development and psychopathology (Print). - : Cambridge University Press. - 0954-5794 .- 1469-2198. ; , s. 1-12
  • Tidskriftsartikel (refereegranskat)abstract
    • Attention-deficit/hyperactivity disorder (ADHD) symptoms are associated with myriad adverse outcomes, including interpersonal difficulties, but factors that moderate the developmental course and functional impact of ADHD over time are not well understood. The present study evaluated developmental contributions of the triarchic neurobehavioral traits (boldness, meanness, and disinhibition) to ADHD symptomatology and its subdimensions from adolescence to young adulthood. Participants were twins and triplets assessed at ages 14, 17, and 19 (initial N = 1,185, 51.2% female). Path analyses using negative binomial regression revealed that boldness at age 14 was associated with more ADHD symptoms cross-sectionally (especially hyperactivity/impulsivity), but fewer symptoms (especially inattention) at age 19 in the prospective analysis. Notably, inclusion of interpersonal problems at ages 14 and 17 as covariates reduced the latter effect to nonsignificant. Disinhibition concurrently and prospectively predicted higher levels of ADHD symptoms, including both subdimensions, and the prospective effects were partially mediated by greater social impairment at age 17. Meanness prospectively (but not concurrently) predicted higher levels of hyperactivity/impulsivity symptoms. Sex moderated certain associations of meanness and disinhibition with ADHD symptoms. These findings highlight how fundamental neurobehavioral traits shape both psychopathology and adaptive outcomes in the developmental course of ADHD.
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7.
  • Euser, Anja S, et al. (författare)
  • Blunted feedback processing during risky decision making in adolescents with a parental history of substance use disorders
  • 2013
  • Ingår i: Development and psychopathology (Print). - : Cambridge University Press. - 0954-5794 .- 1469-2198. ; 25:4 Pt 1, s. 1119-1136
  • Tidskriftsartikel (refereegranskat)abstract
    • Risky decision making, a hallmark phenotype of substance use disorders (SUD), is thought to be associated with deficient feedback processing. Whether these aberrations are present prior to SUD onset or reflect merely a consequence of chronic substance use on the brain remains unclear. The present study investigated whether blunted feedback processing during risky decision making reflects a biological predisposition to SUD. We assessed event-related potentials elicited by positive and negative feedback during performance of a modified version of the Balloon Analogue Risk Task (BART) among high-risk adolescents with a parental history of SUD (HR; n = 61) and normal-risk controls (NR; n = 91). HR males made significantly more risky and faster decisions during the BART than did NR controls. Moreover, HR adolescents showed significantly reduced P300 amplitudes in response to both positive and negative feedback as compared to NR controls. These differences were not secondary to prolonged substance use exposure. Results are discussed in terms of feedback-specific processes. Reduced P300 amplitudes in the BART may reflect poor processing of feedback at the level of overall salience, which may keep people from effectively predicting the probability of future gains and losses. Though conclusions are tentative, blunted feedback processing during risky decision making may represent a promising endophenotypic vulnerability marker for SUD.
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8.
  • Larsson, Johannes, 1993-, et al. (författare)
  • Anger dysregulation and non-suicidal self-injury during adolescence : A test of directionality
  • 2023
  • Ingår i: Development and psychopathology (Print). - : Cambridge University Press. - 0954-5794 .- 1469-2198.
  • Tidskriftsartikel (refereegranskat)abstract
    • Non-suicidal self-injury (NSSI) has been tied to several forms of emotional and behavioral dysregulation in adolescence, with less attention paid to regulation of anger. Most assume that anger dysregulation leads to engagement in NSSI, rather than the reverse. However, it is plausible that NSSI compromises adolescents’ abilities to regulate their emotions, including anger, because it may reduce the development of alternative regulatory strategies and intensify negative emotions by reducing tolerance of distress. Using three waves of data from a sample of adolescents in 17 Swedish schools (n = 1,304 M age = 13.68, SD age = .67; 89% of Swedish origin; 58% girls), we examined the directionality of ties between NSSI and three forms of anger dysregulation: dysregulated expressions of anger, anger suppression, and low anger reflection. We also looked for differences in magnitude of paths and gender differences. Random-intercept cross-lagged panel models showed that NSSI predicted changes in all forms of anger dysregulation but found no support for the opposite direction. Gender differences were not evident. Results challenge directionality assumptions and support suggestions that adolescents’ anger regulation degrades when they self-injure.
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9.
  • O'Reilly, Lauren, et al. (författare)
  • Examining protective factors for substance use problems and self-harm behavior during adolescence : A longitudinal co-twin control study
  • 2022
  • Ingår i: Development and psychopathology (Print). - : Cambridge University Press. - 0954-5794 .- 1469-2198. ; 34, s. 1781-1802
  • Tidskriftsartikel (refereegranskat)abstract
    • Sports participation, physical activity, and friendship quality are theorized to have protective effects on the developmental emergence of substance use and self-harm behavior in adolescence, but existing research has been mixed. This ambiguity could reflect, in part, the potential for confounding of observed associations by genetic and environmental factors, which previous research has been unable to rigorously rule out. We used data from the prospective, population-based Child and Adolescent Twin Study in Sweden (n = 18,234 born 1994-2001) and applied a co-twin control design to account for potential genetic and environmental confounding of sports participation, physical activity, and friendship quality (assessed at age 15) as presumed protective factors for adolescent substance use and self-harm behavior (assessed at age 18). While confidence intervals widened to include the null in numerous co-twin control analyses adjusting for childhood psychopathology, parent-reported sports participation and twin-reported positive friendship quality were associated with increased odds of alcohol problems and nicotine use. However, parent-reported sports participation, twin-reported physical activity, and twin-reported friendship quality were associated with decreased odds of self-harm behavior. The findings provide a more nuanced understanding of the risks and benefits of putative protective factors for risky behaviors that emerge during adolescence.
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10.
  • Silva, Teresa C, et al. (författare)
  • The moderating role of parenting on the relationship between psychopathy and antisocial behavior in adolescence
  • 2016
  • Ingår i: Development and psychopathology (Print). - Cambridge, United Kingdom : Cambridge University Press. - 0954-5794 .- 1469-2198. ; 28:2, s. 505-515
  • Tidskriftsartikel (refereegranskat)abstract
    • We aimed to analyze the impact of several parenting factors on the relationship between psychopathy and antisocial behavior. Nine hundred youths and their mothers reported on parent–youth interactions, and youth self-report measures of psychopathy, delinquency and violent behavior were taken. Multiple regression was used to test for the significance of interactions between parenting and psychopathy scores. In terms of delinquency, linear interactions between psychopathy and the level of conflict with parents and parents’ knowledge of their youths’ whereabouts/youths’ willingness to disclose information were found based on the data reported by the youths. Data reported by mothers indicated a linear interaction between psychopathy and parents’ knowledge/youth disclosure, and a quadratic interaction of conflict with parents. For violence, we used logistic regression models to analyze moderation. No interaction effectsbetween psychopahy scores and parenting factorswere found.Youths’ reports of high conflict with parents and parents’ knowledge/youth disclosure showed to have an impact on violence regardless of the level of psychopathic traits. Implications for the prevention and treatment are discussed.
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