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Norovirus epidemiol...
Norovirus epidemiology in community and health care settings and association with patient age, Denmark
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- Franck, Kristina T (author)
- Danish Serum Institute, Copenhagen
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- Fonager, Jannik (author)
- University of Southern Denmark
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Ersbøll, Annette K (author)
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- Böttiger, Blenda (author)
- Lund University,Lunds universitet,Avdelningen för medicinsk mikrobiologi,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Medical Microbiology,Department of Laboratory Medicine,Faculty of Medicine
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(creator_code:org_t)
- Centers for Disease Control and Prevention (CDC), 2014
- 2014
- English 9 s.
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In: Emerging Infectious Diseases. - : Centers for Disease Control and Prevention (CDC). - 1080-6040 .- 1080-6059. ; 20:7, s. 31-1123
- Related links:
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http://dx.doi.org/10...
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https://doi.org/10.3...
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Abstract
Subject headings
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- Norovirus (NoV) is a major cause of gastroenteritis. NoV genotype II.4 (GII.4) is the predominant genotype in health care settings but the reason for this finding is unknown. Stool samples containing isolates with a known NoV genotype from 2,109 patients in Denmark (patients consulting a general practitioner or outpatient clinic, inpatients, and patients from foodborne outbreaks) were used to determine genotype distribution in relation to age and setting. NoV GII.4 was more prevalent among inpatients than among patients in community settings or those who became infected during foodborne outbreaks. In community and health care settings, we found an association between infection with GII.4 and increasing age. Norovirus GII.4 predominated in patients ≥ 60 years of age and in health care settings. A larger proportion of children than adults were infected with NoV GII.3 or GII.P21. Susceptibility to NoV infection might depend on patient age and infecting NoV genotype. Cohort studies are warranted to test this hypothesis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- Adolescent
- Adult
- Caliciviridae Infections/epidemiology
- Child
- Child, Preschool
- Delivery of Health Care
- Denmark/epidemiology
- Disease Outbreaks
- Feces/virology
- Female
- Food Microbiology
- Genotype
- Humans
- Male
- Middle Aged
- Norovirus/genetics
- RNA, Viral/genetics
- Residence Characteristics
- Sequence Analysis, DNA
- Young Adult
Publication and Content Type
- art (subject category)
- ref (subject category)
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