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Mortality Statistic...
Mortality Statistics Studies of Multiple Sclerosis and Amyotrophic Lateral Sclerosis in Sweden
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- Boström, Inger (författare)
- Linköpings universitet,Neurologi,Hälsouniversitetet
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- Riise, Trond (författare)
- Dept of Public Health and Primary Health Care, University of Bergen, BERGEN, Norway
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- Landtblom, Anne-Marie (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Neurologi,Hälsouniversitetet,Neurologiska kliniken,Division of Neuroscience, Department of Clinical and Experimental Medicine, Linköping University
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(creator_code:org_t)
- 2012-06-05
- 2012
- Engelska.
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Ingår i: Neuroepidemiology. - : S. Karger. - 0251-5350 .- 1423-0208. ; 38:4, s. 245-249
- Relaterad länk:
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https://www.karger.c...
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visa fler...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background: Multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) are chronic neurologic diseases where distinct explanations of the pathogenesis are lacking. Two large Swedish register studies have rather unexpectedly detected a correlation between MS and ALS.The aim of this study was to investigate if an association between ALS and MS could be demonstrated as has been shown earlier.Material and methods: Data on mortality from ALS and MS, 1990-2010 were collected from the Swedish national statistics office. In all there were 5,696 deaths due to ALS and 3,941 deaths due to MS. Age- and sex-adjusted mortality rates were calculated.Results: There was no correlation between the mortality rates of ALS and MS in the 21 counties of Sweden for the period 1990 to 2010 (Spearman’s rho = - 0.052; p = 0.822; n = 21).The national mean mortality rate for ALS throughout the period of 1990 to 2010 was 2.98 per 100 000 person-years (95% CI 2.87 – 3.08). For MS the national mean mortality rate was 2.04 per 100 000 person-years (95% CI 1.95 – 2.12). Both ALS and MS mortality showed significant variation between the counties. Conclusion: This study did not confirm the previously shown association between MS and ALS in Sweden.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Amyotrophic lateral sclerosis; multiple sclerosis; mortality; correlation
- epidemiology
- genetics
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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