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Sökning: L773:1530 0315

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1.
  • Aagaard, Philip, et al. (författare)
  • Early Repolarization in Middle-Age Runners-Cardiovascular Characteristics.
  • 2014
  • Ingår i: Medicine & Science in Sports & Exercise. - 0195-9131 .- 1530-0315. ; 46:7, s. 1285-1292
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: This study aimed to assess the prevalence and patterns of early repolarization (ER) in middle-age long-distance runners, its relation to cardiac structure and function, and its response to strenuous physical activity. Methods: Male first-time cross-country race participants >45 yr were assessed pre-and postrace by medical history and physical examination, 12-lead ECG, vectorcardiography, blood tests, and echocardiography. ER was defined either as ST elevation or J wave and categorized according to localization and morphology. Results: One hundred and fifty-one subjects (50 +/- 5 yr) were evaluated before the race, and 47 subjects were evaluated after the race. Altogether, 67 subjects (44%) had ER. Subjects with versus without ER had a lower resting HR (56 +/- 8 vs 69 +/- 9 bpm, P = 0.02), lower body mass index (24 +/- 2 vs 25 +/- 3 kg.m(-2), P < 0.001), higher training volume (3.0 +/- 2.6 vs 2.1 +/- 2.7 h.wk(-1), P = 0.03), and faster 30-km running times (194 +/- 28 vs 208 +/- 31 min, P = 0.01). Vectorcardiography parameters in subjects with ER showed more repolarization heterogeneity: vector gradient (QRS-T-area) (120 +/- 25 vs 92 +/- 29 mu Vs, P < 0.001), T-area (105 +/- 18 vs 73 +/- 23 mu Vs, P < 0.001), and T-amplitude (0.63 +/- 0.13 vs 0.53 +/- 0.16 mm, P < 0.001); these parameters were inversely related to HR (r = -0.37 to -0.48, P < 0.001). ER disappeared in 15 (75%) of 20 subjects after the race. Conclusions: ER is a common finding in middle-age male runners. This ECG pattern, regardless of morphology and localization, is associated with normal cardiac examinations including noninvasive electrophysiology, features of better physical conditioning, and disappears after strenuous exercise in most cases. These findings support that ER should be regarded as a common and training-related finding also in middle-age physically active men.
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  • Aagaard, P, et al. (författare)
  • Preparticipation Evaluation of Novice, Middle-Age Long-Distance Runners.
  • 2013
  • Ingår i: Medicine and science in sports and exercise. - 0195-9131 .- 1530-0315. ; 45:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Abstract PURPOSE: To assess the cardiovascular health and risk profile in middle-aged males making an entry to participate for their first time in a long-distance race. METHODS: Male first-time participants ≥45 years in the world's largest cross-country running race, the Lidingöloppet, were evaluated with a medical history and physical exam, European risk-SCORE, 12-lead ECG, echocardiography and blood tests. Further diagnostic work-up was performed when clinically indicated. RESULTS: Of 265 eligible runners, 153 (58%, age 51±5 y) completed the study. While the 10-year fatal cardiovascular event risk was low (SCORE: 1% (IQR: 0 - 1%)), mild abnormalities were common, e.g. elevated blood-pressure (19%), left ventricular hypertrophy (6%), elevated LDL cholesterol (5%). ECG changes compatible with "athlete's heart" were present in 82%, e.g. sinus bradycardia (61%) and/or early repolarization (32%). ECG changes considered training-unrelated were found in 24%, e.g. prolonged QTc: 13%; left axis deviation: 5.3%; left atrial enlargement: 4%). In 14 runners (9%) additional diagnostic work-up was clinically motivated, and 4 (2%) were ultimately discouraged from vigorous exercise due to QTc intervals >500 ms (n=2), symptomatic atrioventricular block (n=1), and a cardiac tumor (n=1). The physician exam and the ECG identified 12 of the 14 subjects requiring further evaluation. CONCLUSIONS: Cardiovascular evaluation of middle-aged men, including a physician exam and a 12-lead ECG, appears useful to identify individuals requiring further testing prior to vigorous exercise. The additional yield of routine echocardiography was small.
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  • Ahokas, Essi K., et al. (författare)
  • Nocturnal Heart Rate Variability in Women Discordant for Hormonal Contraceptive Use
  • 2023
  • Ingår i: Medicine & Science in Sports & Exercise. - : Ovid Technologies (Wolters Kluwer Health). - 0195-9131 .- 1530-0315. ; 55:7, s. 1342-1349
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose The aim of this study was to investigate within-cycle differences in nocturnal heart rate (HR) and heart rate variability (HRV) in naturally menstruating women (NM) and women using combined hormonal contraceptives (CU) or progestin-only hormonal contraceptives (PU).Methods Physically active participants were recruited into three groups: NM (n = 19), CU (n = 11), and PU (n = 12). Participants’ HR and HRV (with Bodyguard 2 HRV monitor), and blood hormones were monitored during one menstrual cycle (MC) (NM-group) or for 4 weeks (CU and PU-groups). Estradiol, progesterone, and luteinizing hormone were analyzed from fasting blood samples collected four times in the NM (M1 = bleeding, M2 = follicular phase, M3 = ovulation, and M4 = luteal phase) and PU groups (M1 = lowest E2; M2 = M1 + 7 days; M3 = M1 + 14 days; M4 = M1 + 21 days) and twice in the CU group (active and inactive pill phases). After every blood sample, nightly HR and HRV were recorded and examined as an average from two nights.Results Hormonal concentrations differed (p < 0.05) between MC phases in the NM- and PU-groups, but not (p ≥ 0.116) between the active and inactive phases in the CU-group. In the NM- and PU-groups, some of the HRV values were higher, while in the NM-group, HR was lower during M2 compared to M3 (p < 0.049) and M4 (p < 0.035). In the CU-group, HRV values (p = 0.014-0.038) were higher, and HR was lower (p = 0.038) in the inactive phase compared to the first week of the active phase.Conclusions The MC and hormonal cycle phases influence autonomic nervous system balance, which is reflected in measurements of nocturnal HR and HRV. This should be considered when monitoring recovery in physically active individuals.
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10.
  • Ainegren, Mats, 1963-, et al. (författare)
  • Effects of Aerodynamic Drag and Drafting on Propulsive Force and Oxygen Consumption in Double Poling Cross-Country Skiing
  • 2022
  • Ingår i: Medicine & Science in Sports & Exercise. - 0195-9131 .- 1530-0315. ; 54:7, s. 1058-1065
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose This study aimed to investigate the effects of aerodynamic drag and drafting on propulsive force (FPROP), drag area (CDA), oxygen cost (V˙O2), metabolic rate (Ė), and heart rate (HR) during roller skiing on a treadmill in a wind tunnel using the double poling technique. A secondary aim was to investigate the effects of wind versus no-wind test conditions on the same physiological parameters. Methods Ten subjects of each gender participated in the experiments. One pair of skiers of the same gender roller skied simultaneously in line with the air flow; the distance between the skiers was 2.05 m. Each pair was tested as follows: I) with wind, leading; II) with wind, drafting; and III) without wind. The treadmill inclination was 0° throughout the tests. For the wind conditions, the air velocity was similar to the treadmill belt speed: 3 to 7 m·s-1 for men and 3 to 6 m·s-1 for women. Results Drafting resulted in significantly (P < 0.05) lower FPROP,CDA, V˙O2, and Ė, compared with leading, for both genders at racing speed but not at lower speeds, whereas HR was only affected for the male skiers at racing speed. The test without wind resulted in significantly lower FPROP, V˙O2, and Ė at all tested speeds compared with the tests with wind present, whereas HR was lower only at higher speeds. Conclusions At racing speed, but not at lower speeds, the positive effects of drafting behind a skier during double poling were obvious and resulted in a lower FPROP, CDA, V˙O2, Ė, and HR. Tests without wind present put even lower demands on the skiers' physiology, which was also evident at lower speeds.
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