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Träfflista för sökning "L773:1552 5260 OR L773:1552 5279 ;pers:(Schöll Michael 1980)"

Sökning: L773:1552 5260 OR L773:1552 5279 > Schöll Michael 1980

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Numrering	Referens	Omslagsbild	Hitta
1.	Caroli, Anna, et al. (författare) Alzheimer’s disease core biomarkers and prediction of dementia in MCI: The effect of age at onset 2015 Ingår i: Alzheimer's & Dementia. 11 (7), s. P140-P142. - : Wiley. - 1552-5260. Konferensbidrag (refereegranskat)
2.	Grothe, Michel J., et al. (författare) Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed LATE-NC. 2022 Ingår i: Alzheimer's & dementia : the journal of the Alzheimer's Association. - : Wiley. - 1552-5279. ; 19:4, s. 1234-44 Tidskriftsartikel (refereegranskat)abstract Limbic age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is common in advanced age and can underlie a clinical presentation mimicking Alzheimer's disease (AD). We studied whether an autopsy-derived fluorodeoxyglucose positron emission tomography (FDG-PET) signature of LATE-NC provides clinical utility for differential diagnosis of amnestic dementia patients.Ante mortem FDG-PET patterns from autopsy-confirmed LATE-NC (N = 7) and AD (N = 23) patients were used to stratify an independent cohort of clinically diagnosed AD dementia patients (N = 242) based on individual FDG-PET profiles.Autopsy-confirmed LATE-NC and AD groups showed markedly distinct temporo-limbic and temporo-parietal FDG-PET patterns, respectively. Clinically diagnosed AD dementia patients showing a LATE-NC-like FDG-PET pattern (N = 25, 10%) were significantly older, showed less abnormal AD biomarker levels, lower APOE ε4, and higher TMEM106B risk allele load. Clinically, they exhibited a more memory-predominant profile and a generally slower disease course.An autopsy-derived temporo-limbic FDG-PET signature identifies older amnestic patients whose clinical, genetic, and molecular biomarker features are consistent with underlying LATE-NC.
3.	Heurling, Kerstin, et al. (författare) REGIONAL DIFFERENCES IN THE TRANSIENT EQUILIBRIUM OF [18F]AV-1451 AND THEIR IMPACT ON TISSUE UPTAKE RATIOS 2017 Ingår i: Alzheimer's & Dementia. 13 (7, suppl.), s. P1486-P1487. - : Wiley. - 1552-5260. Konferensbidrag (refereegranskat)
4.	Lockhart, Sam, et al. (författare) Examining relations of age and beta-amyloid with tau deposition measured using 18F-AV-1451 in cognitively normal older adults 2015 Ingår i: Alzheimer's & Dementia. 11 (7), s. P312-P313. - : Wiley. - 1552-5260. Konferensbidrag (refereegranskat)
5.	Lockhart, Samuel N., et al. (författare) EXAMINING AMYLOID AND TAU INTER-REGIONAL PET ASSOCIATION PATTERNS IN COGNITIVELY NORMAL OLDER ADULTS 2016 Ingår i: Alzheimer's & Dementia. 12 (7, suppl.), s. P332-P333. - : Wiley. - 1552-5260. Konferensbidrag (refereegranskat)
6.	Ossenkoppele, Rik, et al. (författare) TAU COVARIANCE PATTERNS IN AD PATIENTS RESEMBLE INTRINSIC CONNECTIVITY NETWORKS IN YOUNG ADULTS 2016 Ingår i: Alzheimer's & Dementia. 12 (7, suppl.), s. P138-P139. - : Wiley. - 1552-5260. Konferensbidrag (refereegranskat)
7.	Ossenkoppele, Rik, et al. (författare) TAU COVARIANCE PATTERNS IN ALZHEIMER'S DISEASE PATIENTS RESEMBLE INTRINSIC CONNECTIVITY NETWORKS IN YOUNG ADULTS 2016 Ingår i: Alzheimer's & Dementia. 12 (7, suppl.), s. P305-P306. - : Wiley. - 1552-5260. Konferensbidrag (refereegranskat)
8.	Rial, Alexis Moscoso, et al. (författare) CSF biomarkers and plasma p-tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial design 2022 Ingår i: Alzheimer's and Dementia. - : Wiley. - 1552-5260 .- 1552-5279. ; 18:12, s. 2614-2626 Tidskriftsartikel (refereegranskat)abstract Introduction: Clinical trials targeting tau in Alzheimer's disease (AD) need to recruit individuals at risk of tau accumulation. Here, we studied cerebrospinal fluid (CSF) biomarkers and plasma phosphorylated tau (p-tau)181 as predictors of tau accumulation on positron emission tomography (PET) to evaluate implications for trial designs. Methods: We included older individuals who had serial tau-PET scans, baseline amyloid beta (Aβ)-PET, and baseline CSF biomarkers (n = 163) or plasma p-tau181 (n = 74). We studied fluid biomarker associations with tau accumulation and estimated trial sample sizes and screening failure reductions by implementing these markers into participant selection for trials. Results: P-tau181 in CSF and plasma predicted tau accumulation (r > 0.36, P <.001), even in AD-continuum individuals with normal baseline tau-PET (A+T–; r > 0.37, P <.05). Recruitment based on CSF biomarkers yielded comparable sample sizes to Aβ-PET. Prescreening with plasma p-tau181 reduced up to ≈50% of screening failures. Discussion: Clinical trials testing tau-targeting therapies may benefit from using fluid biomarkers to recruit individuals at risk of tau aggregation. © 2022 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association
9.	Rodriguez-Vieitez, Elena, et al. (författare) Divergent pattern of changes in astrocytosis and fibrillar amyloid plaques as measured by PET in autosomal-dominant and sporadic Alzheimer’s disease 2015 Ingår i: Alzheimer's & Dementia. 11 (7), s. P86. - : Wiley. - 1552-5260. Konferensbidrag (refereegranskat)
10.	Schonhaut, Daniel, et al. (författare) Associations of [18F]AV1451 Tau PET with age, ApoE genotype, and cognition in Alzheimer’s disease 2015 Ingår i: Alzheimer's & Dementia. 11 (7), s. P265-P266. - : Wiley. - 1552-5260. Konferensbidrag (övrigt vetenskapligt/konstnärligt)

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Resultat 1-10 av 21

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Typ av publikation: konferensbidrag (15); tidskriftsartikel (6)

Typ av innehåll: refereegranskat (20); övrigt vetenskapligt/konstnärligt (1)

Författare/redaktör: Ossenkoppele, Rik (9); Jagust, William J. (8); Hansson, Oskar (5); Blennow, Kaj, 1958 (4); Zetterberg, Henrik, ... (4); Baker, Suzanne L. (4); visa fler...; Jögi, Jonas (4); Smith, Ruben (4); Ashton, Nicholas J. (3); Strandberg, Olof (3); Skoog, Ingmar, 1954 (2); Berron, David (2); Olsson, Tomas (2); Kern, Silke (2); Zettergren, Anna, 19 ... (2); Scheltens, Philip (2); van der Flier, Wiesj ... (2); van Westen, Danielle (2); Karikari, Thomas (2); Nordberg, Agneta (2); Wall, Anders (2); Carter, Stephen F. (2); Almkvist, Ove (1); Westman, E (1); Hilal, S (1); Nilsson, Christer (1); Wahlund, L. O. (1); Långström, Bengt (1); Teunissen, Charlotte ... (1); Pereira, Joana B (1); Barkhof, Frederik (1); Svenningsson, Per (1); Simrén, Joel, 1996 (1); Montoliu-Gaya, Laia (1); Lantero Rodriguez, J ... (1); Snellman, Anniina (1); Volpe, Giovanni, 197 ... (1); Rodriguez-Vieitez, E ... (1); Thordardottir, Stein ... (1); Graff, Caroline (1); Ferrari, Clarissa (1); Caroli, Anna (1); Galluzzi, Samantha (1); Prestia, Annapaola (1); Choo, Il Han (1); Grimmer, Timo (1); Redolfi, Alberto (1); Drzezga, Alexander (1); Heurling, Kerstin (1); Heckemann, Rolf A. (1); visa färre...

Lärosäte: Göteborgs universitet (21); Lunds universitet (2); Karolinska Institutet (1)

Språk: Engelska (21)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (21)

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