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Träfflista för sökning "L773:1613 6810 OR L773:1613 6829 ;pers:(Svedlindh Peter)"

Search: L773:1613 6810 OR L773:1613 6829 > Svedlindh Peter

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1.
  • Österberg, Frederik W, et al. (author)
  • On-Chip Detection of Rolling Circle Amplified DNA Molecules from Bacillus Globigii Spores and Vibrio Cholerae
  • 2014
  • In: Small. - : Wiley. - 1613-6810 .- 1613-6829. ; 10:14, s. 2877-2882
  • Journal article (peer-reviewed)abstract
    • For the first time DNA coils formed by rolling circle amplification are quantified on-chip by Brownian relaxation measurements on magnetic nanobeads using a magnetoresistive sensor. No external magnetic fields are required besides the magnetic field arising from the current through the sensor, which makes the setup very compact. Limits of detection down to 500 Bacillus globigii spores and 2 pM of Vibrio cholerae are demonstrated, which are on the same order of magnitude or lower than those achieved previously using a commercial macro-scale AC susceptometer. The chip-based readout is an important step towards the realization of field tests based on rolling circle amplification molecular analyses.
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2.
  • Zardán Gómez de la Torre, Teresa, et al. (author)
  • Sensitive Detection of Spores Using Volume-Amplified Magnetic Nanobeads
  • 2012
  • In: Small. - : Wiley. - 1613-6810. ; 8:14, s. 2174-2177
  • Journal article (peer-reviewed)abstract
    • A magnetic-nanobead-based, substrate-free method for the sensitive detection of spores in an immunoassay format is presented. The method is shown to detect Bacillus globigii spores, the non-pathogenic simulant of Bacillus anthracis, with a limit-of-detection of 50 spores with a reaction time of 135 min. The study shows the versatility of magnetic nanobeads for detection of biological molecules other than DNA.
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