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Risk factors for ea...
Risk factors for eating disorders : an umbrella review of published meta-analyses.
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- Solmi, Marco (author)
- Universita` di Padova, Padova, Italy; King’s College London, UK
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- Radua, Joaquim (author)
- King’s College London, UK; CIBERSAM, Barcelona, Spain; Karolinska Institute, Sweden
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- Stubbs, Brendon (author)
- South London and Maudsley NHS Foundation Trust, UK; King’s College London, UK; Anglia Ruskin University, Cambridge, UK
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- Ricca, Valdo (author)
- Universita` degli studi di Firenze, Firenze, Italy
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- Moretti, Davide (author)
- Universita` degli studi di Firenze, Firenze, Italy
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- Busatta, Daniele (author)
- Universita` degli studi di Firenze, Firenze, Italy
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- Carvalho, Andre F. (author)
- University of Toronto, Toronto, ON, Canada; Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada
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- Dragioti, Elena, Ph.D. (author)
- Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Smärt och rehabiliteringscentrum
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- Favaro, Angela (author)
- Universita` di Padova, Padova, Italy
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- Monteleone, Alessio Maria (author)
- University of Campania L. Vanvitelli, Naples, Italy
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- Shin, Jae Il (author)
- Yonsei University College of Medicine, Seoul, Republic of Korea
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- Fusar-Poli, Paolo (author)
- King’s College London, London, United Kingdom; South London and Maudsley NHS Foundation Trust, London, United Kingdom; Universita` di Pavia, Pavia, Italy.
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- Castellini, Giovanni (author)
- Universita` degli studi di Firenze, Firenze, Italy
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(creator_code:org_t)
- 2021-06
- 2021
- English.
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In: Revista Brasileira de Psiquiatria. - : Associação Brasileira de Psiquiatria. - 1516-4446 .- 1809-452X. ; 43:3, s. 314-323
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Abstract
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- OBJECTIVE: To grade the evidence about risk factors for eating disorders (anorexia nervosa, bulimia nervosa, and binge eating disorder) with an umbrella review approach.METHODS: This was a systematic review of observational studies on risk factors for eating disorders published in PubMed/PsycInfo/Embase until December 11th, 2019. We recalculated random-effect meta-analyses, heterogeneity, small-study effect, excess significance bias and 95% prediction intervals, grading significant evidence (p < 0.05) from convincing to weak according to established criteria. Quality was assessed with the Assessment of Multiple Systematic Reviews 2 (AMSTAR-2) tool.RESULTS: Of 2,197 meta-analyses, nine were included, providing evidence on 50 risk factors, 29,272 subjects with eating disorders, and 1,679,385 controls. Although no association was supported by convincing evidence, highly suggestive evidence supported the association between childhood sexual abuse and bulimia nervosa (k = 29, 1,103 cases with eating disorders, 8,496 controls, OR, 2.73, 95%CI 1.96-3.79, p = 2.1 x 10-9, AMSTAR-2 moderate quality) and between appearance-related teasing victimization and any eating disorder (k = 10, 1,341 cases with eating disorders, 3,295 controls, OR 2.91, 95%CI 2.05-4.12, p = 1.8x10-9, AMSTAR-2 moderate quality). Suggestive, weak, or no evidence supported 11, 29, and 8 associations, respectively.CONCLUSIONS: The most credible evidence indicates that early traumatic and stressful events are risk factors for eating disorders. Larger collaborative prospective cohort studies are needed to identify risk factors for eating disorders, particularly anorexia nervosa.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- Eating disorders; anorexia nervosa; bulimia nervosa; binge eating disorder: umbrella review; systematic review; meta-analysis; risk factor; prevention
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Solmi, Marco
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Radua, Joaquim
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Stubbs, Brendon
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Ricca, Valdo
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Moretti, Davide
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Busatta, Daniele
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Carvalho, Andre ...
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Dragioti, Elena, ...
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Favaro, Angela
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Monteleone, Ales ...
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Shin, Jae Il
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Fusar-Poli, Paol ...
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Castellini, Giov ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Psychiatry
- Articles in the publication
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Revista Brasilei ...
- By the university
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Linköping University
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Karolinska Institutet