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Träfflista för sökning "L773:1474 547X OR L773:0140 6736 srt2:(1980-1989)"

Sökning: L773:1474 547X OR L773:0140 6736 > (1980-1989)

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1.
  • Hjalmarson, Å, et al. (författare)
  • Effect on mortality of metoprolol in acute myocardial infarction
  • 1981
  • Ingår i: The Lancet. - : The Lancet Publishing Group. - 0140-6736 .- 1474-547X. ; 318:8251, s. 823-827
  • Tidskriftsartikel (refereegranskat)abstract
    • The effect of metoprolol on mortality was compared with that of placebo in a double-blind randomised trial in patients with definite or suspected acute myocardial infarction. Treatment with metoprolol or placebo started as soon as possible after the patient's arrival in hospital and was continued for 90 days. Metoprolol was given as a 15 mg intravenous dose followed by oral administration of 100 mg twice daily. 1395 patients (697 on placebo and 698 on metoprolol) were included in the trial. Definite acute myocardial infarction developed in 809 and probable infarction in 162. Patients were allocated to various risk groups and within each group patients were randomly assigned to treatment with metoprolol or placebo. There were 62 deaths in the placebo group (8·9%) and 40 deaths in the metoprolol group (5·7%), a reduction of 36% (p<0·03). Mortality rates are given according to the treatment group to which the patients were initially randomly allocated.
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2.
  • Winberg, Jan, et al. (författare)
  • The prepuce : a mistake of nature?
  • 1989
  • Ingår i: The Lancet. - : Elsevier Ltd.. - 0140-6736 .- 1474-547X. ; 333:8638, s. 598-599
  • Tidskriftsartikel (refereegranskat)abstract
    • Retrospective studies suggest that circumcision of newborn boys will reduce the frequency of male early infantile urinary tract infection (UTI) by about 90%. If they are correct, this will be the first known instance of a common potentially lethal disease being preventable by extirpation of a piece of normal tissue. To reconcile the phenomenon with existing views of evolution and biology, it is suggested that the effects of one unphysiological intervention are counterbalancing those of another--ie, colonisation of the baby's gastrointestinal tract and genitals in maternity units by Escherichia coli strains of non-maternal origin, to which the baby has no passive immunity. As an alternative to circumcision to prevent early infantile male UTI, more natural colonisation could be promoted by strict rooming-in of mother and baby or by active colonisation of the baby with his mother's anaerobic gut flora.
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3.
  • Islam, M. Shahidul (författare)
  • Drug policy in the Third World
  • 1985
  • Ingår i: The Lancet. - 0140-6736 .- 1474-547X. ; 2:8445, s. 46-47
  • Tidskriftsartikel (refereegranskat)
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  • Resultat 1-10 av 24

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