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Cost-effectiveness ...
Cost-effectiveness of endarterectomy in patients with asymptomatic carotid artery stenosis in Sweden
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- Henriksson, Martin (author)
- Linköpings universitet,Medicinsk teknologiutvärdering,Hälsouniversitetet
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- Lundgren, Fredrik (author)
- Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet
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- Carlsson, Per (author)
- Linköpings universitet,Medicinsk teknologiutvärdering,Hälsouniversitetet
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(creator_code:org_t)
- 2008-04-16
- 2008
- English.
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In: British Journal of Surgery. - Chichester, West Sussex, United Kingdom : John Wiley & Sons. - 0007-1323 .- 1365-2168. ; 95:6, s. 714-720
- Related links:
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http://urn.kb.se/res...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Background: Long-term health outcomes and costs are important when deciding whether a strategy of carotid endarterectomy in addition to best medical management should be recommended for patients with asymptomatic carotid artery stenosis. This study investigated the cost-effectiveness of such a strategy compared with a strategy of best medical management alone.Methods: Based on data from the randomized Asymptomatic Carotid Surgery Trial (ACST), a national vascular database and other published sources, expected costs and health outcomes in terms of quality-adjusted life years (QALYs) of both treatment strategies were estimated using decision-analytical modelling. Cost-effectiveness was established for a Swedish setting from a societal perspective.Results: Base-case analysis showed that the incremental cost per QALY of a strategy with carotid endarterectomy for 65- and 75-year-old men (women) was 34 557 (311 133) and 58 930 (779 776) respectively. Sensitivity analyses indicated that the duration of the treatment effect after 5 years of follow-up in the ACST was important for the cost-effectiveness results.Conclusion: Carotid endarterectomy in addition to best medical management can be considered cost-effective in men aged 73 years or less but is less likely to be cost-effective in older men or in women.
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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