| 1. |
- Ahlgren, Serina, et al.
(author)
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Review of methodological choices in LCA of biorefinery systems - key issues and recommendations
- 2015
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In: Biofuels, Bioproducts and Biorefining. - : Wiley. - 1932-1031 .- 1932-104X. ; 9:5, s. 606-619
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Research review (peer-reviewed)abstract
- The current trend in biomass conversion technologies is toward more efficient utilization of biomass feedstock in multiproduct biorefineries. Many life-cycle assessment (LCA) studies of biorefinery systems have been performed but differ in how they use the LCA methodology. Based on a review of existing LCA standards and guidelines, this paper provides recommendations on how to handle key methodological issues when performing LCA studies of biorefinery systems. Six key issues were identified: (i) goal definition, (ii) functional unit, (iii) allocation of biorefinery outputs, (iv) allocation of biomass feedstock, (v) land use, and (vi) biogenic carbon and timing of emissions. Many of the standards and guidelines reviewed here provide only general methodological recommendations. Some make more specific methodological recommendations, but these often differ between standards. In this paper we present some clarifications (e.g. examples of research questions and suitable functional units) and methodological recommendations (e.g. on allocation).
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| 2. |
- Bring, Arvid, et al.
(author)
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Effects on groundwater storage of restoring, constructing or draining wetlands in temperate and boreal climates: a systematic review
- 2022
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In: Environmental Evidence. - : Springer Science and Business Media LLC. - 2047-2382. ; 11:1
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Research review (peer-reviewed)abstract
- Drainage activities have caused widespread wetland loss, groundwater drawdown and impairment of ecosystem services. There are now several national programs for wetland restoration, primarily focused on reintroducing ecosystem services such as habitats and nutrient retention. In Sweden, recent dry summers have also reinforced interest in hydrological functions such as the potential for enhanced groundwater storage, both in and around the wetland. However, there are several knowledge gaps regarding groundwater storage effects of restoration, including if they extend beyond the wetland and how they vary with local conditions. Therefore, we have systematically reviewed groundwater storage effects from the interventions of restoring, constructing or draining boreo-temperate wetlands. Drainage was included primarily to evaluate to what degree restoration can reverse drainage effects. Methods: We searched 8 databases for scientific journal publications in English, Swedish, Norwegian, Danish, French, German and Polish. Gray literature was searched in English and Swedish. Articles were included based on their relevance for Swedish conditions, i.e., in previously glaciated areas with boreal or temperate climate. Extracted outcome data were groundwater level changes, along with other variables including type of wetland and intervention and, when reported, distance between sampling point and intervention. Meta-analyses were conducted separately for studies that reported groundwater levels at different distances and studies that reported overall effects. Included studies were subject to critical appraisal to evaluate their susceptibility to bias, primarily selection bias, performance bias, and detection bias. Critical appraisal results were used in sensitivity analysis. Review findings: Out of 11,288 screened records, 224 articles fulfilled the criteria, and from these, 146 studies were included in meta-analysis. Most studies (89%) investigated peatlands, primarily from Finland, the UK and Canada. Restoration and drainage studies were equally common. Only nine studies reported measurements beyond the wetland area. Our synthesis is therefore primarily focused on effects within wetlands. In peatland restoration, the observed groundwater level rise decreased exponentially with distance from the restored ditch and was reduced to 50% after 9 [95% confidence interval: 5, 26] m. Drainage reached somewhat farther, with 50% of the groundwater drawdown remaining at 21 [11, 64] m. On average, restoration increased groundwater levels by 22 [16, 28] cm near the intervention, whereas drainage caused a drawdown of 19 [10, 27] cm. Assuming that sampling was unbiased, effects were similar for bogs, fens and mires. Restricting the meta-analysis to the 58% of studies that were of high validity did not alter conclusions. Conclusions: Effects of peatland restoration and drainage were of similar magnitudes but opposite directions. This indicates that, on average, rewetting of drained peatlands can be expected to restore groundwater levels near the ditch. However, restoration may not reach all the area affected by drainage, and there was a strong dependence on local context. For managers of wetland projects, it is thus important to follow up and monitor restoration effects and reinforce the intervention if necessary. Our results also point to a need for better impact evaluation if increased storage beyond the restored wetland area is desired.
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| 3. |
- Bring, Arvid, et al.
(author)
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Groundwater storage effects from restoring, constructing or draining wetlands in temperate and boreal climates: a systematic review protocol
- 2020
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In: Environmental Evidence. - : Springer Science and Business Media LLC. - 2047-2382. ; 9:1
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Research review (peer-reviewed)abstract
- Wetlands in many parts of the world have been degraded, as use of the land for food production and forestry for human needs have taken precedence. Drainage of wetlands has led to deteriorated wetland conditions and lowered water tables. Across the world, there are several programs for wetland restoration and construction, primarily to reintroduce lost habitats for wildlife, and to obtain nutrient retention functions. In Sweden, recent dry and hot summers have reinforced interest in the hydrological functions that wetlands may have, in particular as potential support for water storage in the landscape and added groundwater storage during dry periods. However, the agreement on substantial effects on groundwater is limited, and there are several critical knowledge gaps, including the extent to which such effects extend outside the wetland itself, and how they vary with local conditions, such as topography, soil, and climate. Therefore, this review will address the groundwater storage effect of restoring, constructing or draining wetlands in the boreo-temperate region. Methods: We will conduct a systematic review of the evidence, drawing on both peer-reviewed and grey literature. Articles in English, Swedish, Norwegian, Danish, French, German and Polish will be retrieved from academic databases, Google Scholar, and websites of specialist organizations. We will screen literature in two stages, first at the title and abstract level and then in full text, the latter with blinded decisions by two independent reviewers for all articles. Articles will be included based on relevance criteria for a Swedish context: wetlands on previously glaciated soils in boreal and temperate climates. Data will be extracted from all included articles, including wetland type, intervention type, and hydrogeological setting. Studies will be subject to critical appraisal to evaluate their susceptibility to bias. Provided enough evidence of sufficient reliability, we will carry out meta-analyses of effect sizes in relation to various factors. The review will include a narrative synthesis in which we summarize the results of the review.
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| 4. |
- Gabrielsson, Johan, et al.
(author)
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Dose-Response-Time Data Analysis: An Underexploited Trinity
- 2019
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In: Pharmacological Reviews. - : American Society for Pharmacology & Experimental Therapeutics (ASPET). - 1521-0081 .- 0031-6997. ; 71:1, s. 89-122
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Research review (peer-reviewed)abstract
- The most common approach to in vivo pharmacokinetic and pharmacodynamic analyses involves sequential analysis of the plasma concentration-and response-time data, such that the plasma kinetic model provides an independent function, driving the dynamics. However, in situations when plasma sampling may jeopardize the effect measurements or is scarce, nonexistent, or unlinked to the effect (e.g., in intensive care units, pediatric or frail elderly populations, or drug discovery), focusing on the response-time course alone may be an adequate alternative for pharmacodynamic analyses. Response-timedata inherently contain useful information about the turnover characteristics of response (target turnover rate, half-life of response), as well as the drug's biophase kinetics (biophase availability, absorption half-life, and disposition half-life) pharmacodynamic properties (potency, efficacy). The use of pharmacodynamic time-response data circumvents the need for a direct assay method for the drug and has the additional advantage of being applicable to cases of local drug administration close to its intended targets in the immediate vicinity of target, or when target precedes systemic plasma concentrations. This review exemplifies the potential of biophase functions in pharmacodynamic analyses in both preclinical and clinical studies, with the purpose of characterizing response data and optimizing subsequent study protocols. This article illustrates crucial determinants to the success of modeling dose-response-time (DRT) data, such as the dose selection, repeated dosing, and different input rates and routes. Finally, a literature search was also performed to gauge how frequently this technique has been applied in preclinical and clinical studies. This review highlights situations in which DRT should be carefully scrutinized and discusses future perspectives of the field.
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| 5. |
- Hålldin, Elin, et al.
(author)
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Factors Explaining Interpersonal Variation in Plasma Enterolactone Concentrations in Humans
- 2019
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In: Molecular Nutrition and Food Research. - : Wiley. - 1613-4125 .- 1613-4133. ; 63:16
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Research review (peer-reviewed)abstract
- Lignans are diphenolic plant compounds with potential health modulating properties that are absorbed to the circulation and metabolized to the enterolignans enterodiol (END) and enterolactone (ENL) by gut microbiota. Epidemiological studies have inconsistently shown that a high lignan intake and circulating ENL are associated with reduced risk of breast-, prostate-, and colorectal cancer as well as cardiovascular disease and total and cause-specific mortality. Inconsistencies can be due to interpersonal variation of ENL formation or responses. The aim of this review is to identify and evaluate the impact of factors influencing variability in plasma concentrations of the main enterolignan, ENL. The main determinants of plasma ENL concentrations are intake of lignan and lignan-rich foods, composition and activity of intestinal microflora, antimicrobial use, nutrient intake, BMI, smoking, sex, and age. Composition and activity of the intestinal microbiota appear to be the most critical factor governing interpersonal variability in plasma ENL concentration followed by the use of antibiotics. Future studies with combined data from gut microbiota and metabolomics with food intake and life style data can be used to estimate the relative contribution of the different factors to ENL concentration in quantitative terms.
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| 6. |
- Jonsson, Karin, 1982, et al.
(author)
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Rye and health - Where do we stand and where do we go?
- 2018
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In: Trends in Food Science and Technology. - : Elsevier BV. - 0924-2244 .- 1879-3053. ; 79, s. 78-87
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Research review (peer-reviewed)abstract
- Background: High whole grain intake has consistently been associated with lowered risk of developing a number of chronic diseases. Among cereals, rye has highest content of dietary fiber, together with a wide variety of bioactive compounds. There is accumulating evidence from intervention studies of physiological effects of rye foods with potential health benefits. Scope and approach: This review summarizes the state of the art of rye and health and identifies future directions for research and innovation, based partly on findings presented at the international conference “The Power of Rye” Åland, Finland, 7–8 June 2017. Key findings and conclusions: Rye foods have well-established beneficial effects on insulin metabolism compared with wheat bread under isocaloric conditions and at standardized amounts of available carbohydrates, which may have positive implications for diabetes prevention. Recent findings suggest that alterations in blood glucose flux partly explain these effects. Moreover, several studies have shown beneficial effects of rye-based foods on satiety, which is one plausible mechanism behind recently demonstrated beneficial effects on weight management. Emerging results indicate beneficial effects of rye intake on inflammation and blood lipids. More research is needed to uncover underlying mechanisms for other demonstrated effects and the long-term implications for health. A challenge with rye-based foods is making them palatable and widely acceptable to consumers. Development of innovative and tasty rye products and targeted communication strategies is crucial in increasing awareness and consumption of rye foods. Novel results in this regard are presented in this review.
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| 7. |
- Maia De Souza, Danielle, et al.
(author)
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Ecosystem services in life cycle assessment: A synthesis of knowledge and recommendations for biofuels
- 2018
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In: Ecosystem Services. - : Elsevier BV. - 2212-0416. ; 30, s. 200-210
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Research review (peer-reviewed)abstract
- There is an increasing trend in promoting the use of biofuels for transportation as a low-fossil carbon energy source, but little knowledge on their multidimensional environmental impacts. Whole-system approaches, such as life cycle assessment (LCA), have been extensively employed to analyze the environmental performance of different biofuels. However, it remains unclear to which extent biofuels impact ecosystems and the services they provide, in particular related to different management practices. To overcome this challenge, this paper draws recommendations to better holistically address ecosystem services (ES) in LCA, with a focus on biofuels. We first pinpoint some of the challenges in accounting for the concept of ES in decision-making and review some of the existing ES classification frameworks and the usefulness of the cascade model. Second, we discuss the implications of identified context-specific aspects on the modeling of biofuel production impacts on ES in LCA. Finally, we propose a conceptual framework to link ES classification systems, the cascade model and the LCA approach. Although some challenges still remain unsolved, due to the existing life cycle impact assessment structure, existing ES frameworks and the cascade model are helpful tools to better include ES into LCA of different biofuels.
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| 8. |
- Manach, Claudine, et al.
(author)
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Addressing the inter-individual variation in response to consumption of plant food bioactives: Towards a better understanding of their role in healthy aging and cardiometabolic risk reduction.
- 2017
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In: Molecular nutrition & food research. - : Wiley. - 1613-4133 .- 1613-4125. ; 61:6
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Research review (peer-reviewed)abstract
- Bioactive compounds in plant-based foods have health properties that contribute to the prevention of age-related chronic diseases, particularly cardiometabolic disorders. Conclusive proof and understanding of these benefits in humans is essential in order to provide effective dietary recommendations but, so far, the evidence obtained from human intervention trials is limited and contradictory. This is partly due to differences between individuals in the absorption, distribution, metabolism and excretion of bioactive compounds, as well as to heterogeneity in their biological response regarding cardiometabolic health outcomes. Identifying the main factors underlying inter-individual differences, as well as developing new and innovative methodologies to account for such variability constitute an overarching goal to ultimately optimize the beneficial health effects of plant food bioactives for each and every one of us. In this respect, this position paper from the COST Action FA1403-POSITIVe examines the main factors likely to affect the individual responses to consumption of plant food bioactives and presents perspectives for assessment and consideration of inter-individual variability.
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| 9. |
- Nordborg, Maria, 1985, et al.
(author)
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Energy analysis of willow production for bioenergy in Sweden
- 2018
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In: Renewable and Sustainable Energy Reviews. - : Elsevier BV. - 1879-0690 .- 1364-0321. ; 93, s. 473-482
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Research review (peer-reviewed)abstract
- Energy from biomass, including lignocellulosic crops such as willow (Salix spp.), is expected to increase in importance in Sweden. This study assesses the average annual net energy yield and the ratio between gross energy yield and total primary energy input for well-managed current commercial willow production systems in Sweden subject to three levels of fertilization with mineral nitrogen (N): N-high, N-medium, and N-zero. The average annual net energy yields are estimated at 175, 133, and 86 GJ ha −1 yr −1 , and the (dimensionless) energy ratios are estimated at 19, 32, and 47, for N-high, N-medium, and N-zero, respectively. Thus, there is a trade-off between achieving a high net energy yield and achieving a high energy ratio. Since the total primary energy input amounts to ≤ 5% of the gross energy yield in all cases, and the amount of arable land is limited, productivity increases may be considered more important than energy efficiency improvements. Substantial improvements in energy performance can be achieved by increasing harvest levels and improving energy efficiency in ammonia production and biomass transportation. The results should be interpreted with caution since several input parameters, especially energy use in ammonia production, fuel consumption rates, and the yield response to fertilization, are associated with considerable uncertainties.
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| 10. |
- Nyberg, Gert, et al.
(author)
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Enclosures as a land management tool for food security in African drylands
- 2019
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In: Journal of Land Use Science. - : TAYLOR & FRANCIS LTD. - 1747-4248 .- 1747-423X. ; 14:1, s. 110-121
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Research review (peer-reviewed)abstract
- Increasing sedentary agro-pastoralist livelihoods may be explained by land degradation, population pressure, agricultural commodification, and economic development. We reviewed scientific and ‘grey’ literature for the effects of enclosures on food security. Only 8% of the 114 reviewed scientific articles addressed food production, while 69% approached environmental parameters that indirectly affect food security, most of which had positive results. Thirty-one percent focused on social and economic impacts, land tenure conflicts and elite capture with negative connotations. The ‘grey’ literature showed an opposite balance between positive environmental views and negative socio-economic impacts. Enclosures are not a panacea for dryland development, but their use need to be recognized and understood. Multidisciplinary research and cooperation on the applied management of enclosures in the context of food security is highly needed. Furthermore, agro-pastoralist land-use practices need more policy space and practical management support, such as clear tenure legislation, agroforestry methodologies, and support in fodder production systems.
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