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Sökning: WFRF:(Österström Anna)

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  • Österström, Anna, et al. (författare)
  • Expression of cytosolic and group X secretory phospholipase A(2) genes in human colorectal adenocarcinomas
  • 2002
  • Ingår i: Cancer Letters. - : Elsevier. - 0304-3835 .- 1872-7980. ; 182:2, s. 175-182
  • Tidskriftsartikel (refereegranskat)abstract
    • Gene expression of cytosolic phospholipase A(2) (cPLA(2)) and protein level of secretory PLA(2) group X (sPLA(2)-X) are upregulated in human colorectal cancer and provide cyclooxygenase-2 (COX-2) with arachidonic acid, resulting in increased levels of PGE(2). Mutated ras-genes are suggested to be involved in the regulatory pathway of cPLA(2) in lung cancer cells. We analysed the gene expression of cPLA(2) and sPLA(2)-X in 42 and 38 primary colorectal tumours, respectively, with and without K-ras mutations. We found an up-regulation of cPLA(2) mRNA but the induction in tumour tissues does not correlate with Ras-gene mutations. Moreover, our results cannot consistently reflect an overexpression of sPLA(2)-X gene in colorectal cancer tissues.
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  • Nilsson, Jan-Eric, 1952-, et al. (författare)
  • Arlandabanan : konsekvenser av förändrade strategier
  • 2017
  • Rapport (övrigt vetenskapligt)abstract
    • Detta notat som skrivits på uppdrag av Riksrevisionen har som utgångspunkt att resandet inte utvecklats i enlighet med de prognoser som låg till grund för beslutet om att bygga Arlandabanan. I separata promemorior i detta notat studeras två aspekter av att förändra förutsättningarna för den trafik som idag bedrivs på Arlandabanan. Vilka konsekvenser skulle en förändrad prisstrategi innebära? Finns tillräcklig kapacitet för att öka trafiken?
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  • Ros, Axel, et al. (författare)
  • Improvement work in mental healthcare : an example from Region Jönköping County, Sweden
  • 2020
  • Ingår i: BJPsych International. - : Cambridge University Press. - 2056-4740. ; 17:4, s. 80-82
  • Tidskriftsartikel (refereegranskat)abstract
    • Region Jönköping County (RJC) in Sweden is a healthcare system that is characterised by sustainable work with quality in healthcare and long-term system-wide improvement. This article describes important factors behind the improvement work in RJC, and how the improvement methods and initiatives have been adopted also in mental healthcare. For example, patients otherwise eligible for admission to a psychiatric department were treated at home after introduction of home treatment teams. Patient satisfaction was high and the number of visits to the emergency department, hospital admissions and hospital stay decreased.
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6.
  • Österström, Anna, et al. (författare)
  • Expression of cytosolic and group X secretory phospholipase A2 genes in human colorectal adenocarcinomas
  • 2002
  • Ingår i: Cancer Letters. - 0304-3835 .- 1872-7980. ; 182:2, s. 175-182
  • Tidskriftsartikel (refereegranskat)abstract
    • Gene expression of cytosolic phospholipase A2 (cPLA2) and protein level of secretory PLA2 group X (sPLA2-X) are upregulated in human colorectal cancer and provide cyclooxygenase-2 (COX-2) with arachidonic acid, resulting in increased levels of PGE2. Mutated ras-genes are suggested to be involved in the regulatory pathway of cPLA2 in lung cancer cells. We analysed the gene expression of cPLA2 and sPLA2-X in 42 and 38 primary colorectal tumours, respectively, with and without K-ras mutations. We found an up-regulation of cPLA2 mRNA but the induction in tumour tissues does not correlate with Ras-gene mutations. Moreover, our results cannot consistently reflect an overexpression of sPLA2-X gene in colorectal cancer tissues.
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  • Resultat 1-6 av 6
 
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