| 1. |
- Ademuyiwa, Adesoji O., et al.
(author)
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Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
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In: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
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Journal article (peer-reviewed)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
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| 2. |
- Thomas, HS, et al.
(author)
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- 2019
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swepub:Mat__t
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| 3. |
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| 4. |
- Bhatti, Muhammad Khurram, et al.
(author)
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Locality-aware task scheduling for homogeneous parallel computing systems
- 2018
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In: Computing. - : Springer Science and Business Media LLC. - 0010-485X .- 1436-5057. ; 100:6, s. 557-595
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Journal article (peer-reviewed)abstract
- In systems with complex many-core cache hierarchy, exploiting data locality can significantly reduce execution time and energy consumption of parallel applications. Locality can be exploited at various hardware and software layers. For instance, by implementing private and shared caches in a multi-level fashion, recent hardware designs are already optimised for locality. However, this would all be useless if the software scheduling does not cast the execution in a manner that promotes locality available in the programs themselves. Since programs for parallel systems consist of tasks executed simultaneously, task scheduling becomes crucial for the performance in multi-level cache architectures. This paper presents a heuristic algorithm for homogeneous multi-core systems called locality-aware task scheduling (LeTS). The LeTS heuristic is a work-conserving algorithm that takes into account both locality and load balancing in order to reduce the execution time of target applications. The working principle of LeTS is based on two distinctive phases, namely; working task group formation phase (WTG-FP) and working task group ordering phase (WTG-OP). The WTG-FP forms groups of tasks in order to capture data reuse across tasks while the WTG-OP determines an optimal order of execution for task groups that minimizes the reuse distance of shared data between tasks. We have performed experiments using randomly generated task graphs by varying three major performance parameters, namely: (1) communication to computation ratio (CCR) between 0.1 and 1.0, (2) application size, i.e., task graphs comprising of 50-, 100-, and 300-tasks per graph, and (3) number of cores with 2-, 4-, 8-, and 16-cores execution scenarios. We have also performed experiments using selected real-world applications. The LeTS heuristic reduces overall execution time of applications by exploiting inter-task data locality. Results show that LeTS outperforms state-of-the-art algorithms in amortizing inter-task communication cost.
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| 5. |
- Fakhar-E-Alam, M., et al.
(author)
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Anticancer effects of nanometallic oxides and their ligands with photosensitizers in osteosarcoma cells
- 2015
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In: Journal of Optoelectronics and Advanced Materials. - : NATL INST OPTOELECTRONICS. - 1454-4164 .- 1841-7132. ; 17:11-12, s. 1808-1815
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Journal article (peer-reviewed)abstract
- We studied the cytotoxic effects in Osteosarcoma (U2OS) cells to different nanosized metallic oxides e.g. zinc oxide nanowires (ZnO-NRs), manganese di-oxide nanowires (MnO2 NWs), ferric oxide nanoparticles (Fe2O3 NPs) individually and their connplexed forms with photosensitizers photofrin (R), 5-Aminolevulinic acid (5-ALA), and protoporphyrin IX (Pp IX). Cellular toxicity was assayed by cellular morphology, reactive oxygen species (ROS) detection, MTT assay under ultraviolet (UV), visible light and laser exposed conditions. Prominent cell death with above cited nanomaterials in their complexed forms with Photosensitizer was observed in labeled U2OS cells. This cell death might be due to their synergetic effect via the release of singlet oxygen species in Osteosarcoma cells showing their anticancer-cell effects.
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| 6. |
- Gustavsson, Mikael, et al.
(author)
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A High-Rate Energy-Resolving Photon-Counting ASIC for Spectral Computed Tomography
- 2012
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In: IEEE Transactions on Nuclear Science. - : Institute of Electrical and Electronics Engineers (IEEE). - 0018-9499 .- 1558-1578. ; 59:1, s. 30-39
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Journal article (peer-reviewed)abstract
- We describe a high-rate energy-resolving photon-counting ASIC aimed for spectral computed tomography. The chip has 160 channels and 8 energy bins per channel. It demonstrates a noise level of ENC= electrons at 5 pF input load at a power consumption of andlt;5mW/channel. Maximum count rate is 17 Mcps at a peak time of 40 ns, made possible through a new filter reset scheme, and maximum read-out frame rate is 37 kframe/s.
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| 7. |
- Ul Amin, Farooq, et al.
(author)
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Low-power, high-speed, and low-noise X-ray readout channel in 0.18µm CMOS
- 2010
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In: Proceedings of the 17th International Conference Mixed Design of Integrated Circuits and Systems. - Warsaw : IEEE. - 9781424470112 ; , s. 289-293
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Conference paper (peer-reviewed)abstract
- A 160 channel read-out circuit aimed for a large energy-resolved photon-counting X-ray pixel detector has been designed. The high number of channels combined with high speed and noise performance requires very low power consumption and small footprint of the analog channel. We describe the design of the analog channel, aimed for a detector capacitance of 3-5pF and with a target ENC of 300 electrons for worst case temperature of 100C° at 10ns peaking time and a maximum power consumption of 3 mW/channel.
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| 8. |
- Ul Amin, Farooq, 1982-
(author)
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On the Design of an Analog Front-End for an X-Ray Detector
- 2010. - 1st
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Book (pop. science, debate, etc.)abstract
- Rapid development in CMOS technology has resulted in its suitability for the implementation of readout front-end systems in terms of high integration density, and low power consumption yet at the same time posing many challenges for analog circuits design like readout front-end. One of the significant challenges is the low noise design for high speed front-end systems, while at the same time minimizing the power consumption as much as possible.A high speed, low noise, low power, and programmable readout front-end system is designed and implemented for an X-ray detector in CMOS 0.18 ?m technology in this work. The material in this book is for both professionals in Analog IC Design and students; graduate as well as senior year undergraduate.
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| 9. |
- Bravo, L, et al.
(author)
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- 2021
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swepub:Mat__t
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| 10. |
- Tabiri, S, et al.
(author)
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- 2021
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swepub:Mat__t
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