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- Van Dorsselaere, J. -P, et al.
(författare)
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Status of the SARNET network on severe accidents
- 2010
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Ingår i: International Congress on Advances in Nuclear Power Plants 2010, ICAPP 2010. - 9781617386435 ; , s. 1029-1043
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Konferensbidrag (refereegranskat)abstract
- After four and a half years of operation in the frame of the 6th Framework Programme (FP6) of the European Commission, SARNET (Severe Accidents Research NETwork of excellence) continues in the FP7 (project named SARNET2) from April 2009 for 4 years. Forty-one organisations from 21 countries network their capacities of research in order to resolve the most important remaining uncertainties and safety issues on severe accidents (SA) in existing and future water-cooled nuclear power plants (NPPs). It includes a large majority of the Europeanactors involved in SA research plus a few non-European important ones. The objective is to perform the common research programmes that have been defined in the network first phase and to continue to improve the common computer tools and methodologies for NPP safety assessment. It will consolidate the sustainable integration of the European SA research capacities. These research programmes concern essentially the six highest priority safety issues that were identified after ranking in the first phase of the network: in-vessel core coolability, molten-corium-concrete-interaction, fuel-coolant interaction, hydrogen mixing and combustion in containment, impact of oxidising conditions on source term, and iodine chemistry. The Joint Programme of Activities includes the following main tasks: Performing new experiments on the above mentioned issues andjointly analysing their results in order to elaborate a common understanding of the concerned physical phenomena; Continuing the development and assessment of the ASTEC integral computer code (jointly developed by IRSN and GRS to predict the NPP behaviour during a postulated SA), which capitalizes in terms of models the knowledge produced in the network. In particular efforts are being extended to its applicability to BWR and CANDU NPP types; Continuing the storage of the SA experimental results in a scientific database, based on the STRESA JRC tool; Promoting educational and training courses, ERMSAR (European Review Meeting on Severe Accident Research) international conferences (to be held once a year) and mobility of young researchers or students between the various European organisations. Some R&D results obtained in the first year of the project are presented, in particular: the VULCANO experiment done in CEA mid-2009 on molten-core-corium-interaction, and the release of the first version of the new ASTEC V2 series.
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| 3. |
- Ovaskainen, O., et al.
(författare)
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Combining high-throughput sequencing with fruit body surveys reveals contrasting life-history strategies in fungi
- 2013
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Ingår i: Isme Journal. - : Springer Science and Business Media LLC. - 1751-7362 .- 1751-7370. ; 7:9, s. 1696-1709
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Tidskriftsartikel (refereegranskat)abstract
- Before the recent revolution in molecular biology, field studies on fungal communities were mostly confined to fruit bodies, whereas mycelial interactions were studied in the laboratory. Here we combine high-throughput sequencing with a fruit body inventory to study simultaneously mycelial and fruit body occurrences in a community of fungi inhabiting dead wood of Norway spruce. We studied mycelial occurrence by extracting DNA from wood samples followed by 454-sequencing of the ITS1 and ITS2 regions and an automated procedure for species identification. In total, we detected 198 species as mycelia and 137 species as fruit bodies. The correlation between mycelial and fruit body occurrences was high for the majority of the species, suggesting that high-throughput sequencing can successfully characterize the dominating fungal communities, despite possible biases related to sampling, PCR, sequencing and molecular identification. We used the fruit body and molecular data to test hypothesized links between life history and population dynamic parameters. We show that the species that have on average a high mycelial abundance also have a high fruiting rate and produce large fruit bodies, leading to a positive feedback loop in their population dynamics. Earlier studies have shown that species with specialized resource requirements are rarely seen fruiting, for which reason they are often classified as red-listed. We show with the help of high-throughput sequencing that some of these species are more abundant as mycelium in wood than what could be expected from their occurrence as fruit bodies.
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| 4. |
- Ahola, Virpi, et al.
(författare)
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The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera
- 2014
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 5, s. 4737-
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Tidskriftsartikel (refereegranskat)abstract
- Previous studies have reported that chromosome synteny in Lepidoptera has been well conserved, yet the number of haploid chromosomes varies widely from 5 to 223. Here we report the genome (393 Mb) of the Glanville fritillary butterfly (Melitaea cinxia; Nymphalidae), a widely recognized model species in metapopulation biology and eco-evolutionary research, which has the putative ancestral karyotype of n = 31. Using a phylogenetic analyses of Nymphalidae and of other Lepidoptera, combined with orthologue-level comparisons of chromosomes, we conclude that the ancestral lepidopteran karyotype has been n = 31 for at least 140 My. We show that fusion chromosomes have retained the ancestral chromosome segments and very few rearrangements have occurred across the fusion sites. The same, shortest ancestral chromosomes have independently participated in fusion events in species with smaller karyotypes. The short chromosomes have higher rearrangement rate than long ones. These characteristics highlight distinctive features of the evolutionary dynamics of butterflies and moths.
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| 5. |
- Salojarvi, Jarkko, et al.
(författare)
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Genome sequencing and population genomic analyses provide insights into the adaptive landscape of silver birch
- 2017
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Ingår i: Nature Genetics. - : NATURE PUBLISHING GROUP. - 1061-4036 .- 1546-1718. ; 49:6, s. 904-912
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Tidskriftsartikel (refereegranskat)abstract
- Silver birch (Betula pendula) is a pioneer boreal tree that can be induced to flower within 1 year. Its rapid life cycle, small (440-Mb) genome, and advanced germplasm resources make birch an attractive model for forest biotechnology. We assembled and chromosomally anchored the nuclear genome of an inbred B. pendula individual. Gene duplicates from the paleohexaploid event were enriched for transcriptional regulation, whereas tandem duplicates were overrepresented by environmental responses. Population resequencing of 80 individuals showed effective population size crashes at major points of climatic upheaval. Selective sweeps were enriched among polyploid duplicates encoding key developmental and physiological triggering functions, suggesting that local adaptation has tuned the timing of and cross-talk between fundamental plant processes. Variation around the tightly-linked light response genes PHYC and FRS10 correlated with latitude and longitude and temperature, and with precipitation for PHYC. Similar associations characterized the growth-promoting cytokinin response regulator ARR1, and the wood development genes KAK and MED5A.
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