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Occupational complexity and cognition in the FINGER multidomain intervention trial

Rydström, Anders (author)
Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Karolinska Institutet; Stockholm University,Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
Darin-Mattsson, Alexander (author)
Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Aging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
Kåreholt, Ingemar, 1960- (author)
Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Jönköping University, Jönköping, Sweden,Karolinska Institutet; Stockholm University; Jönköping University,HHJ, Institutet för gerontologi,HHJ. ARN-J (Aging Research Network - Jönköping)
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Ngandu, Tiia (author)
Karolinska Institutet
Lehtisalo, Jenni (author)
Finnish Institute of Health & Welfare, FIN; University Eastern Finland, FIN,Department of Public Health Solutions, Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
Solomon, Alina (author)
Karolinska Institutet
Antikainen, Riitta (author)
University Oulu, FIN; Oulu University Hospital, FIN; Oulu City Hospital, FIN,Center for Life Course Health Research/Geriatrics, University of Oulu, Oulu, Finland
Bäckman, Lars (author)
Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Aging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
Hanninen, Tuomo (author)
Kuopio University Hospital, FIN,Neurocenter/Neurology, Kuopio University Hospital, Kuopio, Finland
Laatikainen, Tiina (author)
Finnish Institute of Health & Welfare, FIN; University of Eastern Finland, FIN; Hospital District of North Karelia, Joensuu, FIN,Department of Public Health Solutions, Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
Levalahti, Esko (author)
Department of Public Health Solutions, Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
Lindström, Jaana (author)
Department of Public Health Solutions, Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
Paajanen, Teemu (author)
Finnish Institute of Occupational Health, FIN,Work Ability and Working Careers, Finnish Institute of Occupational Health, Helsinki, Finland
Havulinna, Satu (author)
Department of Welfare; Ageing, Disability and Functioning Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
Peltonen, Markku (author)
Karolinska Institutet; Finnish Institute of Health & Welfare, FIN,Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
Sindi, Shireen (author)
Karolinska Institutet
Soininen, Hilkka (author)
University of Eastern Finland, FIN; Kuopio University Hospital, FIN,Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
Stigsdotter Neely, Anna, 1961- (author)
Karlstads universitet,Institutionen för sociala och psykologiska studier (from 2013)
Strandberg, Timo (author)
University of Oulu, FIN; University of Helsinki, FIN; Helsinki University Hospital, FIN,Center for Life Course Health Research/Geriatrics, University of Oulu, Oulu, Finland
Tuomilehto, Jaakko (author)
Finnish Institute of Health & Welfare, FIN; South Ostrobothnia Central Hospital, FIN; University of Helsinki, Helsinki, FIN; King Abdulaziz University, SAU,Department of Public Health Solutions, Public Health Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
Kivipelto, Miia (author)
Karolinska Institutet
Mangialasche, Francesca (author)
Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Karolinska Institutet; Stockholm University,Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
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 (creator_code:org_t)
2022-02-09
2022
English.
In: Alzheimer's & Dementia. - : John Wiley & Sons. - 1552-5260 .- 1552-5279. ; 18:12, s. 2438-2447
Related links:
https://doi.org/10.1...
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https://kau.diva-por... (primary) (Raw object)
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  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Introduction Lifetime exposure to occupational complexity is linked to late-life cognition, and may affect benefits of preventive interventions. Methods In the 2-year multidomain Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER), we investigated, through post hoc analyses (N = 1026), the association of occupational complexity with cognition. Occupational complexity with data, people, and substantive complexity were classified through the Dictionary of Occupational Titles. Results Higher levels of occupational complexity were associated with better baseline cognition. Measures of occupational complexity had no association with intervention effects on cognition, except for occupational complexity with data, which was associated with the degree of intervention-related gains for executive function. Discussion In older adults at increased risk for dementia, higher occupational complexity is associated with better cognition. The cognitive benefit of the FINGER intervention did not vary significantly among participants with different levels of occupational complexity. These exploratory findings require further testing in larger studies.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Geriatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Geriatrics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)

Keyword

Alzheimer's disease
cognitive decline
cognitive reserve
dementia
intelligence
multidomain intervention
occupational complexity
prevention
randomized controlled trials
Psykologi inr. medicinsk psykologi
Psychology with an emphasis on medical psychology

Publication and Content Type

ref (subject category)
art (subject category)

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