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Differences in Risk...
Differences in Risk Factor Patterns Between Cervical and Trochanteric Hip Fractures
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- Michaëlsson, Karl, 1959- (author)
- Uppsala universitet,Ortopedi,Orthopaedics
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Weiderpass, E. (author)
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Farahmand, Bahman Y. (author)
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Baron, John A. (author)
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Persson, P-G (author)
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Ziden, L. (author)
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Zetterberg, C. (author)
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- Ljunghall, Sverker (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,osteo
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(creator_code:org_t)
- Springer Science and Business Media LLC, 1999
- 1999
- English.
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In: Osteoporosis International. - : Springer Science and Business Media LLC. - 0937-941X .- 1433-2965. ; 10:6, s. 487-494
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- The two types of hip fracture--cervical and trochanteric femoral fractures--are generally considered together in etiologic studies. However, women with a trochanteric fracture may be more osteoporotic than those with cervical hip fractures, and have higher post-fracture mortality. To explore differences in risk factor patterns between the two types of hip fracture we used data from a large population-based case-control study in Swedish women, 50-81 years of age. Data were collected by questionnaire, to which more than 80% of subjects responded. Of the cases included, 811 had had a cervical fracture and 483 a trochanteric fracture during the study period; these cases were compared with 3312 randomly selected controls. Height and hormonal factors appeared to affect the risk of the two types of hip fracture differently. For every 5 cm of current height, women with a cervical fracture had an adjusted odds ratio (OR) of 1.23 (95% CI 1.15-1.32) compared with an OR of 1.06 (95% CI 0.97-1.15) for women with trochanteric fractures. Later menopausal age was protective for trochanteric fractures (OR 0.95, 95% CI 0. 91-0.99 per 2 years) but no such association was found for cervical fractures. Compared with never smokers, current smokers had an OR of 1.48 (95% CI 1.12-1.95) for trochanteric fractures and 1.22 (95% CI 0.98-1.52) for cervical fractures. Current hormone replacement therapy was similarly protective for both fracture types, but former use substantially reduced risk only for trochanteric fractures: OR 0. 55 (95% CI 0.33-0.92) compared with 1.00 (95% CI 0.71-1.39) for cervical fractures. These risk factor patterns suggest etiologic differences between the fracture types which have to be considered when planning preventive interventions.
Keyword
- Cervical
- Estrogen
- Height
- Hip fracture
- Trochanteric
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
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