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Ambient Air Polluti...
Ambient Air Pollution and Adult Asthma Incidence in Six European Cohorts (ESCAPE)
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Jacquemin, Benedicte (author)
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Siroux, Valerie (author)
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Sanchez, Margaux (author)
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Carsin, Anne-Elie (author)
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Schikowski, Tamara (author)
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Adam, Martin (author)
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Bellisario, Valeria (author)
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Buschka, Anna (author)
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Bono, Roberto (author)
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Brunekreef, Bert (author)
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Cai, Yutong (author)
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Cirach, Marta (author)
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Clavel-Chapelon, Francoise (author)
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Declercq, Christophe (author)
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de Marco, Roberto (author)
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de Nazelle, Audrey (author)
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Ducret-Stich, Regina E. (author)
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Ferretti, Virginia Valeria (author)
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Gerbase, Margaret W. (author)
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Hardy, Rebecca (author)
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Heinrich, Joachim (author)
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- Janson, Christer (author)
- Uppsala universitet,Lungmedicin och allergologi
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Jarvis, Deborah (author)
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Al Kanaani, Zaina (author)
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Keidel, Dirk (author)
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Kuh, Diana (author)
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Le Moual, Nicole (author)
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Nieuwenhuijsen, Mark J. (author)
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Marcon, Alessandro (author)
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- Modig, Lars (author)
- Umeå universitet,Yrkes- och miljömedicin
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Pin, Isabelle (author)
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Rochat, Thierry (author)
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Schindler, Christian (author)
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Sugiri, Dorothea (author)
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Stempfelet, Morgane (author)
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Temam, Sofia (author)
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Tsai, Ming-Yi (author)
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Varraso, Raphaelle (author)
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Vienneau, Danielle (author)
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Vierkoetter, Andrea (author)
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Hansell, Anna L. (author)
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Kraemer, Ursula (author)
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Probst-Hensch, Nicole M. (author)
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Sunyer, Jordi (author)
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Kuenzli, Nino (author)
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Kauffmann, Francine (author)
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(creator_code:org_t)
- Environmental Health Perspectives, 2015
- 2015
- English.
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In: Journal of Environmental Health Perspectives. - : Environmental Health Perspectives. - 0091-6765 .- 1552-9924. ; 123:6, s. 613-621
- Related links:
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https://ehp.niehs.ni...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- BACKGROUND: Short-term exposure to air pollution has adverse effects among patients with asthma, but whether long-term exposure to air pollution is a cause of adult-onset asthma is unclear. OBJECTIVE: We aimed to investigate the association between air pollution and adult onset asthma. METHODS: Asthma incidence was prospectively assessed in six European cohorts. Exposures studied were annual average concentrations at home addresses for nitrogen oxides assessed for 23,704 participants (including 1,257 incident cases) and particulate matter (PM) assessed for 17,909 participants through ESCAPE land-use regression models and traffic exposure indicators. Meta-analyses of cohort-specific logistic regression on asthma incidence were performed. Models were adjusted for age, sex, overweight, education, and smoking and included city/area within each cohort as a random effect. RESULTS: In this longitudinal analysis, asthma incidence was positively, but not significantly, associated with all exposure metrics, except for PMcoarse. Positive associations of borderline significance were observed for nitrogen dioxide [adjusted odds ratio (OR) = 1.10; 95% CI: 0.99, 1.21 per 10 mu g/m(3); p = 0.10] and nitrogen oxides (adjusted OR = 1.04; 95% CI: 0.99, 1.08 per 20 mu g/m(3); p = 0.08). Nonsignificant positive associations were estimated for PM10 (adjusted OR = 1.04; 95% CI: 0.88, 1.23 per 10 mu g/m(3)), PM2.5 (adjusted OR = 1.04; 95% CI: 0.88, 1.23 per 5 mu g/m(3)), PM2.5absorbance (adjusted OR = 1.06; 95% CI: 0.95, 1.19 per 10(-5)/m), traffic load (adjusted OR = 1.10; 95% CI: 0.93, 1.30 per 4 million vehicles x meters/day on major roads in a 100-m buffer), and traffic intensity (adjusted OR = 1.10; 95% CI: 0.93, 1.30 per 5,000 vehicles/day on the nearest road). A nonsignificant negative association was estimated for PMcoarse (adjusted OR = 0.98; 95% CI: 0.87, 1.14 per 5 mu g/m(3)). CONCLUSIONS: Results suggest a deleterious effect of ambient air pollution on asthma incidence in adults. Further research with improved personal-level exposure assessment (vs. residential exposure assessment only) and phenotypic characterization is needed.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
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- art (subject category)
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- By the author/editor
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Jacquemin, Bened ...
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Siroux, Valerie
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Sanchez, Margaux
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Carsin, Anne-Eli ...
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Schikowski, Tama ...
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Adam, Martin
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show more...
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Bellisario, Vale ...
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Buschka, Anna
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Bono, Roberto
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Brunekreef, Bert
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Cai, Yutong
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Cirach, Marta
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Clavel-Chapelon, ...
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Declercq, Christ ...
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de Marco, Robert ...
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de Nazelle, Audr ...
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Ducret-Stich, Re ...
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Ferretti, Virgin ...
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Gerbase, Margare ...
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Hardy, Rebecca
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Heinrich, Joachi ...
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Janson, Christer
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Jarvis, Deborah
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Al Kanaani, Zain ...
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Keidel, Dirk
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Kuh, Diana
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Le Moual, Nicole
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Nieuwenhuijsen, ...
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Marcon, Alessand ...
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Modig, Lars
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Pin, Isabelle
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Rochat, Thierry
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Schindler, Chris ...
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Sugiri, Dorothea
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Stempfelet, Morg ...
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Temam, Sofia
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Tsai, Ming-Yi
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Varraso, Raphael ...
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Vienneau, Daniel ...
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Vierkoetter, And ...
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Hansell, Anna L.
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Kraemer, Ursula
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Probst-Hensch, N ...
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Sunyer, Jordi
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Kuenzli, Nino
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Kauffmann, Franc ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Respiratory Medi ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
- Articles in the publication
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Journal of Envir ...
- By the university
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Uppsala University
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Umeå University