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Träfflista för sökning "WFRF:(Blangero J) srt2:(2010-2014);pers:(Lorentzon Mattias 1970)"

Search: WFRF:(Blangero J) > (2010-2014) > Lorentzon Mattias 1970

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  • Liu, Ching-Ti, et al. (author)
  • Assessment of gene-by-sex interaction effect on bone mineral density
  • 2012
  • In: Journal of Bone and Mineral Research. - : Wiley. - 1523-4681 .- 0884-0431. ; 27:10, s. 2051-2064
  • Journal article (peer-reviewed)abstract
    • Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is widely observed; however, the extent to which genes explain these sex differences is unclear. To identify variants with different effects by sex, we examined gene-by-sex autosomal interactions genome-wide, and performed expression quantitative trait loci (eQTL) analysis and bioinformatics network analysis. We conducted an autosomal genome-wide meta-analysis of gene-by-sex interaction on lumbar spine (LS) and femoral neck (FN) BMD in 25,353 individuals from 8 cohorts. In a second stage, we followed up the 12 top single-nucleotide polymorphisms (SNPs; p?
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